Filtyp
Oxidative stress, or the production of oxygen-centered free radicals, has been hypothesized as the major source of DNA damage that in turn can lead to altered genetic expression, disease, and aging of humans. Serum protein thiol levels in blood are a direct measure of the in vivo reduction/oxidation (redox) status in humans, because thiols react readily with oxygen-containing free radicals to form
Natural killer (NK) cells are involved both in control of virus infections and in elimination of tumor cells. Killer immunoglobulin-like receptors (KIRs) either activate or inhibit NK cell-mediated cytolysis, protecting healthy cells from destruction while enabling killing of abnormal cells. To investigate whether KIR genes or genotypes are associated with cervical carcinogenesis, a nested case-co
Objective: To investigate if administration of CNI-1493, an inhibitor of the synthesis of proinflammatory cytokines and NO, protects against development of joint destruction in collagen induced arthritis ( CIA) in rats. Methods: In a placebo controlled experiment, CNI-1493 was given once daily intraperitoneally after onset of clinical arthritis in DA rats. Disease progression was studied by clinic
We have identified and characterized a human endogenous retrovirus (HERV) gag transcript in the human pre-B cell leukemia line Reh. The transcript was found to be a splice product of a structurally intact HERV element located on chromosome 6q13. Its primer binding site is complementary to phenylalanine (F) tRNA, common for the HERV-F family, but the overall genome sequence is closely related to th
Enterprise Systems Implementation Methodology (ESIM) is considered to be a critical factor for successful Enterprise Systems (ES) implementations. In spite of ESIM’s potential and significance for practice, little attention has been paid to this object of study in ES literature. Current studies reveal contradictory findings regarding its potential value and provide a fragmented understanding of it
In the 1990s, Japanese energy regulators were concerned by the fact that new generations of energy using appliances and products no longer displayed successive use-phase energy efficiency improvements, such as those that characterised product development in Japan after the 1970s oil crises. Therefore, in 1999, Japan incepted its Top Runner programme, designed to rejuvenate the lost momentum. Sever
This chapter starts with a description of the optics of camera-type eyes, in which an image is projected upon a retina with cornea and lens as refracting elements. Ray tracing is explained with the human eye as an example of a terrestrial vertebrate's eye. Then the comparison is made to camera eyes of aquatic and amphibious animals, with an explanation of different kinds of aberrations, difficulti
The word “desertification” was introduced in 1949 by the French scientist Aubreville in his report “Climats, forêts et désertification de l´Afrique tropicale”. The concept, however, was discussed earlier by European and American scientists in terms of increased sand movements, desiccation, desert and Sahara encroachment and man made deserts. Desertification, at the beginning of last century, mea
A frame of reference is presented intended to capture conditions that influence the usability of information technologies, primarily computers, in a society. The frame of reference includes four components that influence one another: 1. External physical conditions, 2. Economic resources (including other technological resources), 3. Social actors and their interests, and 4. the Understanding, con
Moisture transport in concrete under a temperature gradient is a topic that has challenged researchers for at least some 60 years. No conclusions are still drawn on how to describe it theoretically and how to quantify it experimentally. In this paper some of the theoretical and experimental work done is summarized. A description of the flux of moisture by the relative humidity and the water vapour
We argue that the group-centred analyses of social epidemiology should follow from theoretical considerations that take the situation of the individual as their natural starting point. In a tentative dialogue between economics and sociology, we develop a framework for the analysis of health-related behaviour. Such behaviour is modelled as a process of decision-making at the individual level. Withi
Abstract in German Nach ihrem Amtsamtritt im September 2006 hat die schwedische Mitte-Rechts-Regierung im Januar 2007 die Beiträge zu den Arbeitslosenkassen der Gewerkschaften erheblich erhöht. Dadurch wurde es plötzlich wesentlich teurer, Mitglied in einer Gewerkschaft (und in der Arbeitslosenkasse) zu sein. Innerhalb von zwei Jahren verloren die Gewerkschaften 8% ihrer Mitglieder, der gewerkschaIn January 2007 the Swedish centre-right government in office since September 2006 raised considerably fees for union unemployment funds. Union membership (fund membership included) therefore suddenly became much more expensive. Trade unions lost 8% of their members over two years and union density fell by 6 percentage points (from 77% in 2006 to 71% in 2008), while unemployment funds were hit by
The results are presented of a detailed plant macrofossil analysis of a C-14 dated Holocene organic sequence from a sub-Antarctic island, South Georgia. In the peat infilling of a rock basin 31 bryophyte species and many of the principal species of the present-day angiosperm flora, associated with bog communities, have been identified. The zonation of the bryophytes and the seeds and fruits shows
Changes in Faroese land surfaces during the late Holocene reflect intimate interactions between cultural and environmental development. Analyses of fossil wood, pollen and plant macrofossils indicate that the present open landscape replaced shrubby vegetation that was present from c. 6000 BC Up to c. AD 660. Conditions altered during the late Holocene, with loss of woody vegetation and increasing
There is considerable loss of DM during wet heat treatment of vegetables, leading to an increase in dietary fibre. Correction for the loss of DM indicates that the effects on total dietary fibre are minor. There is, however, depolymerization of the dietary fibre polysaccharides. The degradation is related to the severity of the heat treatment. Souring, freezing and mild microwave treatment have no
Purpose: This study described person–environment (P–E) fit and activities of daily living (ADLs) among older adults, and it explored the relationship between P–E fit and ADL dependence, testing Lawton's docility hypothesis at two points in time. Design and Methods: From a random sample of individuals aged 75–84 living in a Swedish municipality, 72 persons were available for baseline and follow-up
Popular Abstract in Swedish Nästan 35% av den totala avrinningen i Gula floden härstammar från dess källområde och vattenförsörjningen nedströms är därför beroende av de rådande förhållandena i detta område. Minskad vattenföring i floden på grund av klimatförändringar förväntas leda till negativa konsekvenser för de 110 miljoner invånarna i avrinningsområdet och problem uppstår för såväl jordbrukeThe source region of the Yellow River contributes about 35% of the total water yield in the Yellow River basin playing an important role for meeting the downstream water resources requirements. The declining water availability caused by climate change in the source region of the Yellow River is expected to have severe repercussions for the 110 million basin inhabitants in terms of water resources
BACKGROUND: The minor T allele of rs2943641 near the gene encoding for insulin receptor substrate 1 (IRS1) has been associated with decreased risk of type 2 diabetes (T2D) and adiposity in genome-wide association studies. Dietary intake can influence the regulation of IRS1, and studies have indicated sex-specific associations between IRS1 and adiposity. OBJECTIVE: The objective was to examine the
