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ECG markers derived from the P-wave are used frequently to assess atrial function and anatomy, e.g. left atrial enlargement. While having the advantage of being routinely acquired, the processes underlying the genesis of the P-wave are not understood in their entirety. Particularly the distinct contributions of the two atria have not been analyzed mechanistically. We used an in silico approach to
This paper presents numerical and experimental investigations of the structure and stabilization of a low swirl turbulent stratified lean premixed methane/air flame. Large-eddy simulations are performed using a two-scalar flamelet model based on mixture fraction for predicting the stratification in the fuel/air mixture and a level-set G-function for tracking the flame. Measurements are carried out
The aim of this study was to assess the ability of different mouse diets to sustain an H. pylori infection in BALB/cA mice. Four commercially available mouse diets were compared. Experiment 1: Mice were fed the four diets for seven days before infection, infected three times at two-day intervals with 0.1 ml of 10(9) colony-forming units/ml H. pylori cells. H. pylori strains (n = 4) were cultured o
In this study, we assessed the proliferative response of peripheral blood mononuclear leukocytes (PBML) from 33 children/young adolescents with chronic dyspepsia, to H. pylori LPS in the presence and absence of IL-2 as a T cell growth factor. A rapid urease test (RUT) and a presence of Helicobacter-like organisms (HLO) in the biopsy specimens allowed us to distinguish RUT/HLO-positive (17/33) and
Autoantibodies to insulin (IAA) are one of the first markers of the autoimmune process leading to type 1 diabetes (T1D). While other autoantibodies in T1D have been studied extensively, relatively little is known about IAA and their binding specificities, especially after insulin treatment is initiated. We hypothesize that insulin antibodies (IA) that develop upon initiation of insulin treatment d
In arterial vessel wall characterisation the longitudinal movements of vessels have gained little or no attention. It has been presumed that the arterial vessels move very little in the longitudinal direction. With modern high resolution ultrasound it can, however, be seen that arterial vessels move not only in the circumferential, but also in longitudinal direction. This paper describes a non-inv
We present and discuss the Cs 3d X-ray absorption spectra and resonant photoelectron emission spectra of CsF. The resonant photoelectron spectra excited at the Cs 3d absorption maxima, exhibit a strong resonance behavior. The different behaviour of participator and spectator channels and interference effects of the 4d partial photoionisation cross-section at the 3d resonances are discussed. The ex
This report provides a compendium of current information relating to radiation dose to patients, including biokinetic models, biokinetic data, dose coefficients for organ and tissue absorbed doses, and effective dose for major radiopharmaceuticals based on the radiation protection guidance given in Publication 60 (ICRP, 1991). These data were mainly compiled from Publications 53 , 80, and 106 (ICR
Synergistic interplay between Mycobacterium tuberculosis (Mtb) and HIV in coinfected ind-ividuals leads to the acceleration of both tuberculosis and HIVdisease. Mtb, as well as HIV, may modulate the function of many immune cells, including DCs. To dissect the bystander impact of Mfs infected with Mtb on DC functionality, we here investigated changes in DC phenotype, cytokine profiles, and HIV-1 tr
A prospective clinical cohort study was established to investigate the humoral immune response in middle ear fluids (MEF) and serum against bacterial surface proteins in children suffering from recurrent acute otitis media (rAOM) and chronic otitis media with effusion (COME), using Luminex xMAP technology. The association between the humoral immune response and the presence of Moraxella catarrhali
This study is done within the framework of a project aimed at developing a wearable device (a bracelet) intended to support sensory motor rehabilitation of children with visual impairments. We present an exploratory study of aesthetic/hedonistic preferences for sounds and touch experiences among visually impaired children. The work is done in a participatory setting, and we have used mixed methods
A novel approach to background/foreground segmentation using an online EM algorithm is presented. The method models each layer as a Gaussian mixture, with local, per pixel, parameters for the background layer and global parameters for the foreground layer, utilising information from the entire scene when estimating the foreground. Additionally, the online EM algorithm uses a progressive learning r
Recent observations of the NN Serpentis post-common envelope binary system have revealed eclipse timing variations that have been attributed to the presence of two Jovian-mass exo-planets. Under the assumption that these planets are real and survived from the binary's main-sequence state, we reconstruct initial binaries that give rise to the present NN Ser configuration and test the dynamical stab
A fully integrated differential class-AB power amplifier has been designed in a 0.25 um CMOS technology. It is intended for medium output power ranges such as Bluetooth class 1, and has an operating frequency of 2.45 GHz. By using two parallel output stages that can be switched on or off, a high efficiency can be achieved for both high and low output power levels. The simulated maximum output powe
Today many methods are available for gas turbine flow path analysis. Some of them are very simple but yet very useful, since they give an indication of the compressor capacity with almost no calculation effort. The state of the art today is the heat and mass balance models (HMB), which are more sophisticated. This paper presents a general overview of these methods, including the most recent trend,
BACKGROUND: The earliest immune events induced by allergens are poorly understood, yet are likely essential to understanding how allergic inflammation is established. OBJECTIVE: We sought to describe the earliest signaling events activated by allergen and determine their significance to allergic inflammation. METHODS: A fungal-associated allergenic proteinase (FAP) or ovalbumin was administered on
A new sample-and-hold circuit based on the charge sampling technique is introduced, which integrates input current instead of tracking input voltage to realize high speed and low voltage sampling. Both the theoretical analysis and the experimental results prove that it can realize both sample-and-hold and amplification functions. A 500 MS/s charge sampling circuit is implemented in 0.25 μm CMOS pr
Sorption isotherms (moisture content as a function of relative humidity (RH) at equilibrium) are an important tool in designing buildings to limit moisture related problems. Normally only a single sorption curve is used so that each moisture content uniquely corresponds to one RH. Sometimes two curves are used, one curve for absorption and one for desorption, as it is well known that sorption has
