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Putative role of polymorphisms in UCP1-3 genes for diabetic nephropathy.

Increased production of reactive oxygen species (ROS) has been suggested as a cause of diabetic complications. Uncoupling proteins (UCPs) have been ascribed a role in reducing the formation of ROS, and genetic variation in genes encoding for UCPs could thus be putative candidate genes for diabetic nephropathy. To test this hypothesis we searched for association between the A→G (−3862) variant in U

ONO-8815Ly, an EP2 agonist that markedly inhibits uterine contractions in women.

Objective To determine the effect of ONO-8815Ly on uterine contractions. Design A randomised, double-blind, placebo-controlled, dose-ascending, cross-over study. Setting Department of Obstetrics and Gynaecology, University Hospital of Lund, Sweden. Population Seventeen, healthy, parous and permanently sterilised women. Methods Intrauterine pressure was recorded on days 1-3 of bleeding of two m

Correlated production of p and (p)over-bar in Au+Au collisions at root s(NN)=200 GeV

Correlations between p and (p) over bar at transverse momenta typical of enhanced baryon production in Au + Au collisions are reported. The PHENIX experiment has measured same and opposite sign baryon pairs in Au + Au collisions at root s(NN) = 200 GeV. Correlated production of p and p with the trigger particle from the range 2.5 < p(T) < 4.0 GeV/c and the associated particle with 1.8 < p(T) < 2.5

Electric dipole strength below the giant dipole resonance

Recent experimental findings and theoretical approaches to the electric dipole (El) strength distribution below the particle emission threshold at shell closures are revisited. Results from photon scattering experiments are discussed and compared to predictions within the quasiparticle-phonon nuclear model. An analysis of the fine structure of the El strength is presented. Recent studies of the E1

Temporal changes in the elemental composition of Rhizopogon rhizomorphs during colonization of patches with fresh organic matter or acid-washed sand

A laboratory experiment was performed to estimate the elemental composition of rhizomorphs of an ectomycorrhizal (EM) fungus growing in a patchy environment. Successive samples of Rhizopogon rhizomorphs, located adjacent to patches with organic matter or patches with acid-washed sand, were taken over a period of 45 d. The mass per unit area was analyzed with scanning transmission ion microscopy (S

Impulse noise and continuous noise of equivalent frequency spectrum and total sound energy

It has been proposed that impulse noise and continuous noise affect the inner ear differently and investigations have found impulse noise to be harmful to both the inner hair cells and the outer hair cells. Scanning electron microscopy and non-standard methods for statistical analysis have facilitated the evaluation of different types of morphological changes after exposure to various kinds of noi

Transition probabilities and lifetimes in gold (Au I and Au II)

Radiative lifetimes of three odd-parity levels of neutral gold (Au I) and one odd-parity level of singly ionized gold (Au II), measured using the time-resolved laser-induced fluorescence technique, have allowed the testing of the reliability of a relativistic Hartree-Fock model of the atomic structure taking configuration interaction and core-polarization effects into account. The importance of th

Demonstrating stratification in a European American population

Population stratification occurs in case-control association studies when allele frequencies differ between cases and controls because of ancestry. Stratification may lead to false positive associations, although this issue remains controversial(1-4). Empirical studies have found little evidence of stratification in European-derived populations, but potentially significant levels of stratification

Karyotypic differences and evolutionary tendencies of some species from the subgenus Obliquodesmus Mlad. of genus Scenedesmus Meyen (Chlorophyta, Chlorococcales)

Karyotype structures of Scenedesmus acuminatus (Lagerch.) Chod. and Scenedesmus pectinatus Meyen are compared. The karyotype of S. acuminatus (n = 5) is described for the first time. It reveals four large metacentric and one large submeta centric chromosomes (4M + 1SM). The established karyotype differences have been helpful in clarifying the taxonomic position of these two species. The cytologica

Management from four different perspectives

AIM: This study intended to illuminate nursing management in a developing organization from the perspectives of nurse managers, chief physicians, hospital directors and politicians. BACKGROUND: Increased responsibility in a changing health care system makes it important that nurses occupy advantageous positions so that they may safeguard and facilitate the development of their core area. METHODS:

Global Changes and European Terrestrial Ecosystems

Global environmental changes are topics of important societal concern and current scientific interest. These changes are driven by many different forcing and feedbacks occurring at various time and geographic scales and are largely influencing the various Earth systems. Despite the fact that the natural component of these changes has always occurred, today it's the anthropogenic component and its

Practices for preparing children for clinical examinations and procedures in Swedish pediatric wards.

This study sought to elucidate Swedish pediatric wards concerning the practice of informing children and their parents about clinical examinations and procedures. A semi-structured questionnaire was distributed to all 36 pediatric departments in Sweden, comprising of 83 wards. Fifty-eight (70%) of the wards responded. The results showed that 55 (95%) of the wards provided regular planned informati

Farmers as innovators

This working paper analyses the mindset and driving forces of innovators in the agricultural sector. The key drivers and incentives are different in this group than for the innovators from academic institution. Therefor the interaction with risk capital providers becomes problematic.

Behandling av artros. Etiologi och patofysiologi vid artros - terapeutiska konsekvenser

Artros (i engelskt språkbruk ”osteoarthritis”, ibland ”osteoarthrosis”) är en sjukdom med sakta förlopp och ibland gradvis försämring. Sjukdomen kan leda till total förstöring av leden och behov av operation med ersättning av leden med konstgjort material. För de flesta patienter med artros blir kirurgisk behandling dock aldrig nödvändig, besvären kan behandlas bra på annat sätt.Artros är inte en

Measured and predicted behaviour of steel beams and columns in fire

Analytical predictions of mechanical behaviour of fire-exposed steel structures are compared to experimental results obtained from three different research laboratories. Comparisons are made to axially free and restrained steel columns fire tested in Metz in France 1973-74, to simply supported steel beams fire tested in Germany and published in Stahlbau 1/1983 and to axially free and restrained st

Chemiluminescence of 1,2-dioxetane. Reaction mechanism uncovered

The thermal decomposition of 1,2-dioxetane and the associated production of chemiluminescent products, model for a wide range of chemiluminescent reactions, has been studied at the multistate multiconfigurational second-order perturbation level of theory. This study is in qualitative and quantitative agreement with experimental observations with respect to the activation energy and the observed in

Epicardial right atrial free wall mapping in chronic atrial fibrillation. Documentation of repetitive activation with a focal spread--a hitherto unrecognised phenomenon in man

BACKGROUND: Previous studies have shown that atrial fibrillation of recent onset in man is based on a varying number of simultaneously present activation waves reentering either themselves or each other. In the present study, right atrial activation during chronic atrial fibrillation in man was studied. METHODS AND RESULTS: In 16 patients with chronic atrial fibrillation multiple epicardial record

Evaluation of low-energy tailing parameters of a HPGe X-ray detector to be used in GUPIX software library for PIXE analysis

Accurate description of the response function of X-ray detectors is important for quantitative PIXE analysis. For analytical description of low-energy tailing in PIXE spectra, the GUPIX approach was used, i.e. a combination of Hypermate type functions. The low-energy tailing parameters of a low-energy high purity germanium X-ray detector in the region 1.3-9.2 keV was determined by systematic fitti