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OBJECTIVE: To monitor changes in family physicians' reported practice on hypertension and hypercholesterolaemia. DESIGN: Random samples of physicians were selected for telephone interviews on their practice regarding cut-off levels and pharmacological treatment of hypertension and hypercholesterolaemia, related to a case scenario of a 48-year-old man, in 1989, 1991 and 1993. SETTING: Primary care
Animal models of neurological deficits are essential for the assessment of new therapeutic options. It has been suggested that rats are not as appropriate as primates for the symptomatic modelling of disease, but a large body of data argues against this view. Comparative analyses of movements in rats and primates show homology of many motor patterns across species. Advances have been made in ident
A new predictive formula for the total longshore sediment transport (LST) rate was developed from principles of sediment transport physics assuming that breaking waves mobilize the sediment, which is subsequently moved by a mean current. Six high-quality data sets on hydrodynamics and sediment transport collected during both field and laboratory conditions were employed to evaluate the predictive
We obtain a relation between the time between two bird-catchings and the total resting period of a bird, leading to the problem of estimating the derivative of a convex density. We state a fundamental result on the nonparametric maximum likelihood estimator of a convex density. Further, we derive the optimal rate in the minimax risk sense for estimating the derivative of a convex density.
In this paper, return migration from Sweden to three sources of refugee immigration is analysed, with a focus on the effect of political change in 1990. Chilean immigrants reacted more strongly to political liberalization in the home country than Polish immigrants did, primarily due to more favourable economic circumstances in Chile compared to Poland in the 1990s. In fact, the increase in Polish
Expression of the human cysteine proteinase inhibitor, cystatin C (CysC) in the cytoplasm of Escherichia coli was studied using a cDNA fragment encoding the cysteine proteinase inhibitor controlled by the phage λ pImage /cI857 system. The yield of CysC was low, probably due to proteolytic degradation. By fusing the cysC cDNA to a DNA fragment encoding the signal peptide of the E. coli outer membra
PURPOSE: The reduced size of abdominal aortic aneurysms (AAAs) after endovascular repair suggests lowered intraaneurysmal pressure. In the presence of endoleaks, the size is not decreased. Although postoperative intraaneurysmal pressure is difficult to record, the pulsatile wall motion (PWM) of aneurysms can be measured noninvasively. The aim of this study was to assess the PWM of AAAs before and
Abstract is not available
The processes of intraepithelial migration, intraluminal seeding, and field cancerization as models for initiation, spread, and recurrences of urothelial cell carcinoma (UCC) are reviewed in light of recent molecular investigations. The accumulated molecular data on synchronous and metachronous tumors indicate that the majority of recurrent and multiple tumors are monoclonal. Molecular data has al
The focus of this paper is to derive the symbol error probability (SEP) of a Rake receiver with a limited number of fingers that track the strongest multipath components in a frequency-selective Rayleigh fading channel. We develop an analytical framework that allows the computation of the SEP for nonuniform power dispersion profiles (PDPs) and spreading bandwidth. By transforming the physical Rake
Popular Abstract in Swedish Hur kan man förklara vardagligt tänkande med de kognitiva teorier som finns tillhands idag? Ofta är dessa teorier konstruerade för att kunna förutsäga beteende under kontrollerade omständigheter, som i ett laboratorium. Å andra sidan är det snarare flexibilitet och improvisation som kännetecknar det vardagliga tänkandet. I avhandlingen försöker jag ta reda pa vad man måHow well can we explain natural occurrences of cognitive behaviours given the theoretical frameworks available to us today? The thesis explores what has to be assumed in cognitive theory in order to provide such an explanation, in contrast to being able to predict behaviour under controlled circumstances. The behaviours considered are all of the type described as involving higher level cognition
An appropriate animal model is essential to study Helicobacter pylori infection. The aim of this study was to investigate if H. pylori can colonise the guinea-pig stomach and whether the infection causes gastritis and a serological response similar to that observed in man. Guinea-pigs were infected either with fresh H. pylori isolates from human gastric biopsies or with a guinea-pig passaged strai
1 Organ culture has been shown to upregulate both endothelin (ET) and 5-hydroxytryptamine 1B/1D (5-HT(1B/1D)) receptors in rat cerebral arteries. The purpose of the present study was to investigate the involvement of protein kinases, especially protein kinases C (PKC) and A (PKA) in this process. 2 The effect of inhibiting protein kinases during organ culture with staurosporine (unspecific protein
