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Dietary patterns, nutritional profile, and body mass index in Mexican schoolchildren : A cross-sectional study

Childhood obesity is a serious public health problem in Mexico. In this study, childhoodspecific dietary patterns and their relationship with overweight-obesity prevalence, nutrient profiles and types of foods consumed were studied. A descriptive cross-sectional study of 724 randomly selected schoolchildren between 9 to 12 years old from Nayarit State, Mexico was performed. Data on anthropometric

Cardiovascular risk after hospitalisation for unexplained syncope and orthostatic hypotension

OBJECTIVE: To investigate the relationship of hospital admissions due to unexplained syncope and orthostatic hypotension (OH) with subsequent cardiovascular events and mortality.METHODS: We analysed a population-based prospective cohort of 30 528 middle-aged individuals (age 58±8 years; males, 40%). Adjusted Cox regression models were applied to assess the impact of unexplained syncope/OH hospital

Multimodal-first or pantomime-first? : Communicating events through pantomime with and without vocalization

A persistent controversy in language evolution research has been whether language emerged in the gestural-visual or in the vocal-auditory modality. A "dialectic" solution to this age-old debate has now been gaining ground: language was fully multimodal from the start, and remains so to this day. In this paper, we show this solution to be too simplistic and outline a more specific theoretical propo

Differences in the epigenetic and reprogramming properties of pluripotent and extra-embryonic stem cells implicate chromatin remodelling as an important early event in the developing mouse embryo

Background. During early mouse development, two extra-embryonic lineages form alongside the future embryo: the trophectoderm (TE) and the primitive endoderm (PrE). Epigenetic changes known to take place during these early stages include changes in DNA methylation and modified histones, as well as dynamic changes in gene expression. Results. In order to understand the role and extent of chromatin-b

Visualization of lipid directed dynamics of perilipin 1 in human primary adipocytes

Perilipin 1 is a lipid droplet coating protein known to regulate lipid metabolism in adipocytes by serving as a physical barrier as well as a recruitment site for lipases to the lipid droplet. Phosphorylation of perilipin 1 by protein kinase A rapidly initiates lipolysis, but the detailed mechanism on how perilipin 1 controls lipolysis is unknown. Here, we identify specific lipid binding propertie

Hydrogen sulphide poisoning of shallow seas following the end-Triassic extinction

The evolution of complex life over the past 600 million years was disrupted by at least five mass extinctions, one of which occurred at the close of the Triassic period. The end-Triassic extinction corresponds to a period of high atmospheric-CO 2 concentrations caused by massive volcanism and biomass burning; most extinction scenarios invoke the resulting environmental perturbations in accounting

Climatic factors and species range position predict sexually antagonistic selection across taxa

Sex differences in selection are ubiquitous in sexually reproducing organisms. When the genetic basis of traits is shared between the sexes, such sexually antagonistic selection (SAS) creates a potential constraint on adaptive evolution. Theory and laboratory experiments suggest that environmental variation and the degree of local adaptation may all affect the frequency and intensity of SAS. Here,

Forum : In the beginning there was no word (For It): Terms, concepts, and early sovereignty

It is difficult to overstate the importance of the concept sovereignty for international relations (IR). And yet, understanding the historical emergence of sovereignty in international relations has long been curtailed by the all-encompassing myth of the Peace of Westphalia. While criticism of this myth has opened space for further historical inquiry in recent years, it has also raised important q

Re-inforcing the cell death army in the fight against breast cancer

Metastatic breast cancer is responsible for most breast cancer-related deaths. Disseminated cancer cells have developed an intrinsic ability to resist anchorage-dependent apoptosis (anoikis). Anoikis is caused by the absence of cellular adhesion, a process that underpins lumen formation and maintenance during mammary gland development and homeostasis. In healthy cells, anoikis is mostly governed b

Gender

My chapter gives an overview of gender and religion in Europe in the “long” 19th century based on developments in historical research since the 1980s. The focus is on Catholicism and Protestantism with some reflexions also on Judaism and Orthodox Christianity.

Rare inborn errors of metabolism with movement disorders : a case study to evaluate the impact upon quality of life and adaptive functioning

BACKGROUND: Inborn errors of metabolism (IEM) form an important cause of movement disorders in children. The impact of metabolic diseases and concordant movement disorders upon children's health-related quality of life (HRQOL) and its physical and psychosocial domains of functioning has never been investigated. We therefore conducted a case study on the HRQOL and development of adaptive functionin

Domain-Informed Spline Interpolation

Standard interpolation techniques are implicitly based on the assumption that the signal lies on a single homogeneous domain. In contrast, many naturally occurring signals lie on an inhomogeneous domain, such as brain activity associated to different brain tissue. We propose an interpolation method that instead exploits prior information about domain inhomogeneity, characterized by different, pote

Permanent pacemaker implantation early and late after heart transplantation : clinical indication, risk factors and prognostic implications

BACKGROUND: Permanent pacemaker implantation (PPM) early after cardiac transplantation has been shown not to predict a worse outcome. However, the requirement for pacing late after transplantation and its prognostic implications are not fully known. We describe the clinical indications, risk factors and long-term outcome in patients who required pacing early and late after transplantation.METHODS:

Evaluation of simulation-assisted value stream mapping for software product development : Two industrial cases

Context: Value stream mapping (VSM) as a tool for lean development has led to significant improvements in different industries. In a few studies, it has been successfully applied in a software engineering context. However, some shortcomings have been observed in particular failing to capture the dynamic nature of the software process to evaluate improvements i.e. such improvements and target value

Utvärdering av dubbdäcksförbudets effekt på luftkvaliteten på Friggagatan

I syfte att utvärdera effekten av dubbdäcksförbudet på Friggagatan med avseende på luftkvaliteten har Miljöförvaltningen i Göteborg på uppdrag av trafikkontoret i Göteborg utfört luftkvalitetsmätningar på Friggagatan mellan 2013-01-01 och 2013-09-30. Dessutom utförde Miljöförvaltningen mätningar av dubbdäcksanvändningen på Friggagatan, vid Drottningtorget och i Haga. Vidare användes även mätdata f

Brominated Flame Retardants and Organophosphate Esters in Preschool Dust and Children's Hand Wipes

Children spend a considerable part of their day in preschool, where they may be exposed to hazardous chemicals in indoor dust. In this study, brominated flame retardants (BFRs) and organophosphate esters (OPEs) were analyzed in preschool dust (n = 100) and children's hand wipe samples (n = 100), and diphenyl phosphate (DPHP) was analyzed in urine (n = 113). Here we assessed children's exposure via

Product design and business model strategies for a circular economy

The transition within business from a linear to a circular economy brings with it a range of practical challenges for companies. The following question is addressed: What are the product design and business model strategies for companies that want to move to a circular economy model? This paper develops a framework of strategies to guide designers and business strategists in the move from a linear

Evaluation of three energy balance-based evaporation models for estimating monthly evaporation for five lakes using derived heat storage changes from a hysteresis model

The heat storage changes (Q t) can be a significant component of the energy balance in lakes, and it is important to account for Q t for reasonable estimation of evaporation at monthly and finer timescales if the energy balance-based evaporation models are used. However, Q t has been often neglected in many studies due to the lack of required water temperature data. A simple hysteresis model (Q t