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Background: Carry Life UF is a novel peritoneal dialysis (PD) technology for improved fluid management using steady concentration PD (SCPD). The Carry Life UF treatment starts with a manual peritoneal fill of 1.36% glucose PD fluid, followed by a 5-hour treatment where small amounts of glucose are continuously added to maintain a stable intraperitoneal glucose concentration. A recent in-center cli

A new setup for burning velocity measurements of liquid fuels at elevated pressures using the Heat Flux method has been constructed. The burner design has been improved comparing to previous studies in this and other laboratories. Laminar burning velocities were determined experimentally for ethanol+air and methanol+air mixtures over a range of conditions including equivalence ratio (0.8 to 1.3),

Children spend a considerable part of their day in preschool, where they may be exposed to hazardous chemicals in indoor dust. In this study, brominated flame retardants (BFRs) and organophosphate esters (OPEs) were analyzed in preschool dust (n = 100) and children's hand wipe samples (n = 100), and diphenyl phosphate (DPHP) was analyzed in urine (n = 113). Here we assessed children's exposure via

The transition within business from a linear to a circular economy brings with it a range of practical challenges for companies. The following question is addressed: What are the product design and business model strategies for companies that want to move to a circular economy model? This paper develops a framework of strategies to guide designers and business strategists in the move from a linear

α-Galactosidases are important industrial enzymes for hemicellulosic biomass degradation or modification. In this study, six novel extracellular α-galactosidases from Penicillium subrubescens were produced in Pichia pastoris and characterized. All α-galactosidases exhibited high affinity to pNPαGal, and only AglE was not active towards galacto-oligomers. Especially AglB and AglD released high amou

When two putatively cryptic species meet in nature, hybrid zone analysis can be used to estimate the extent of gene flow between them. Two recently recognized cryptic species of banded newt (genus Ommatotriton) are suspected to meet in parapatry in Anatolia, but a formal hybrid zone analysis has never been conducted. We sample populations throughout the range, with a focus on the supposed contact

RationaleThere is no effective disease modifying treatment for peanut allergy available. A Phase I safety and tolerability study was performed with a chemically modified, Al(OH)3 adsorbed peanut extract (HAL-MPE1) for subcutaneous immunotherapy (SCIT).MethodsIn a randomized, double-blind, placebo controlled, single-centre, Phase I study, 17 Caucasian subjects with peanut allergy were randomized to

Municipal biowaste has a high potential for agricultural use. However, it requires an additional amendment to increase the nutritional content used during the composting process. The purpose of this study was to investigate the selection of compost-enhancing amendments from municipal biowaste using bibliometric and multicriteria analysis. The municipality of Yopal (Casanare, Colombia) was chosen a

In this article, we analyze the nexus between political regimes and external voting rights. Using a global longitudinal dataset, we report that higher levels of inclusion and contestation bring higher probabilities that a state adopts and implements emigrant enfranchisement. Taking outliers from our quantitative assessment, we then further examine two liberal democracies, Ireland and Uruguay, and

In scenarios coined Maxwell's demon, information on microscopic degrees of freedom is used to seemingly violate the second law of thermodynamics. This has been studied in the classical as well as the quantum domain. In this paper, we study an implementation of Maxwell's demon that can operate in both domains. In particular, we investigate information-to-work conversion over the quantum-to-classica

The role of natural marine aerosols in the global climate system remains understudied and uncertain. This is true for the emissions of natural volatile compounds over the ocean, the oxidation of said compounds and their impact on particle formation and particle growth. In this thesis, the emission, chemistry and aerosol particle processes relating to these compounds were studied using different pr

Carbon emissions from buildings have inherently dynamic characteristics since buildings evolve over time. Most previous studies, however, implemented static building carbon regimes, ignoring the temporal variation of many factors that govern carbon emissions of buildings. This research explores the influences of four dynamic factors acting on building carbon emissions: dynamic climate change data,

This chapter takes an interest in the world of platforms for creative and cultural work. Platforms for creative and cultural work started to become popular in the late 20th century, and their popularity has grown rapidly over the years. Taking its point of departure from these platforms, this chapter aims to shed light upon and discuss the work of the professionals who handle and manage these platThis chapter takes an interest in the world of platforms for creative and cultural work. Platforms for creative and cultural work started to become popular in the late 20th century, and their popularity has grown rapidly over the years. Taking its point of departure from these platforms, this chapter aims to shed light upon and discuss the work of the professionals who handle and manage these plat

Hypoxia hampers eutrophication reduction efforts by enabling high nutrient fluxes from sediment to bottom waters. Oxygenation of hypoxic water bodies is often proposed to reduce benthic ammonium and phosphate release. This study investigates the functional response of benthic nitrate-reducing processes to a long-term engineered oxygenation effort in a density-stratified fjord with euxinic bottom w

The popliteal artery (PA) is, after aorta, the most common site for aneurysm formation. Why the PA is more susceptible than other peripheral muscular arteries is unknown. We hypothesized that the wall composition, which in turn affects wall properties, as well as the circumferential wall stress (WS) imposed on the arterial wall, might differ compared to other muscular arteries. The aim was to stud

. The aim of this article is to provide an up-to-date overview on paediatric haemophilia care in the world, with emphasis on medical treatment, rehabilitation, and orthopaedic surgery. The reason these specific professions caregivers are included is that over 90% of bleeding episodes in people with haemophilia (PWH) occur within the musculoskeletal system; and of these 80% of bleedings occur in jo

The aim of this study was to estimate the prevalence of frequent knee pain in radiographic, symptomatic and clinically defined knee OA in middle-aged and elderly patients and the proportion that seeks medical care.

Cinnamoyl-CoA reductase (CCR), an enzyme central to the lignin biosynthetic pathway, represents a promising biotechnological target to reduce lignin levels and to improve the commercial viability of lignocellulosic biomass. However, silencing of the CCR gene results in considerable flux changes of the general and monolignol-specific lignin pathways, ultimately leading to the accumulation of variou