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We give a new proof of the Nirenberg-Treves conjecture: that local solvability of principal type pseudodifferential operators is equivalent to condition (Psi). This condition rules out sign changes from - to + of the imaginary part of the principal symbol along the oriented bicharacteristics of the real part. We obtain local solvability by proving a localizable a priori estimate for the adjoint op
The idea for nature based research design emerged in preparation of a workshop and subsequent exhibition regarding minimal surfaces, supervised by Andreas Hopf, Senior Lecturer at Lund University School of Industrial Design, and supported by Prof. Dr. Konrad Polthier (Chair Mathematical Geometry Processing, FU Berlin) at the DESIGNMAI digital crafts event in Berlin in 2007, for which Swedish desig
Gas turbine maintenance is crucial due to high cost for the replacement of its components and associated loss of power during shutdown period. Conventional scheduled maintenance, based on equivalent operating hours, is not the best alternative as it can require unnecessary shut downs. Condition based maintenance is an attractive alternative as it decreases unnecessary shut downs and has other adva
Human islet amyloid polypeptide (hIAPP), a pancreatic islet protein of 37 amino acids, is the main component of islet amyloid, seen at autopsy in patients with type 2 diabetes mellitus (DM2). To investigate the roles of hIAPP and islet amyloid in DM2, we generated transgenic mice expressing hIAPP in their islet beta cells. In this study, we found that after a long-term, high-fat diet challenge isl
Popular Abstract in Swedish Stroke är en vanlig och mycket allvarlig form av hjärt-kärlsjukdom som uppkommer på grund av försämrat blodflöde i en del av hjärnan. Eftersom hjärnan är extremt beroende av kontinuerlig tillförsel av syre och näringsämnen leder tillståndet snabbt till hjärnskada. Det finns tre typer av stroke; hjärninfarkt, hjärnblödning och subaraknoidalblödning (blödning under en hjäThe present thesis aimed to examine how ischemic stroke affects the vascular endothelin and angiotensin systems in cerebral arteries. To study vascular receptor changes in ischemic stroke transient focal ischemia was induced in rats. In addition, rat cerebral arteries and arterial smooth muscle cells were cultured for further analysis of cerebrovascular receptor regulation. For functional studies
Fiona Björling Introduction Andrzej Xalicki Polish conceptions of the intelligentsia and its calling Steven J. Seegel Cartography and the collected nation in Joachim Lelewel’ Lelewel’s geographical imagination: a revised approach to intelligentsia S. I. Michal´cenko xxx V. B. Evarouskij (Evorovskij) xxx Michail Dolbilov Stereotypes of the Pole in Russian public discourse: the case of Russific
This paper presents results of a production experiment testing the recursivity of prosodic realization of focus in Tokyo Japanese. Tokyo Japanese wh-questions obligatorily exhibit focus prosody, which starts from a wh-phrase (WH) and continues until the question particle (Q) that binds the wh-phrase (Deguchi and Kitagawa 2002; Ishihara 2002, 2003). The current study examines the case where one WH–
While influenza vaccines aim to decrease the incidence of severe influenza among high-risk groups, evidence of influenza vaccine effectiveness (IVE) among the influenza vaccine target population is sparse. We conducted a multicentre test-negative case–control study to estimate IVE against hospitalised laboratoryconfirmed influenza in the target population in 18 hospitals in France, Italy, Lithuani
Background:Computed tomographic angiography (CTA) may require a non-contrast enhanced dataset for the diagnostic workup. By using dual-energy acquisition, it is possible to obtain a virtual non-contrast-enhanced (VNC) dataset, thereby possibly eliminating the non-contrast acquisition and reducing the radiation dose.Purpose:To compare image quality of VNC images reconstructed from arterial phase du
Many predictive models exist that predict risk of common cardiometabolic conditions. However, a vast majority of these models do not include genetic risk scores and do not distinguish between clinical risk requiring medical or pharmacological interventions and pre-clinical risk, where lifestyle interventions could be first-choice therapy. In this study, we developed, validated, and compared the pe
Many exemplary projects have demonstrated that Nature-based Solutions (NBS) can contribute to climate change adaptation, but now the challenge is to scale up their use. Setting realistic policy goals requires knowing the amount of different NBS types that can fit in the urban space and the benefits that can be expected. This research aims to assess the potential for a full-scale implementation of
BACKGROUND: Radiostereometric analysis (RSA) is a highly accurate tool to detect implant migration and predict loosening following total knee arthroplasty (TKA). However, little is known about the predisposing risk factors for implant migration, nor which migration profile should be considered physiological (i.e., merely part of an implant-settling phase) and which should be considered pathologica
The unprecedented scale of the Covid-19 pandemic has been a challenge for health supply chains around the world. Many international humanitarian organizations have had to ensure the continuity of their already complex development programs, while addressing their supply chain disruptions linked to the pandemic. Process modularity has frequently been advocated as a strategy to mitigate such disrupti
The Rodinia supercontinent broke apart during the Neoproterozoic. Rodinia break-up is associated with widespread intraplate magmatism on many cratons, including the c. 720–719 Ma Franklin large igneous province (LIP) of Laurentia. Coeval magmatism has also been identified recently in Siberia and South China. This extensive magmatism terminates ∼1 myr before the onset of the Sturtian Snowball Earth
In clinical trials, surrogate endpoints, that are more cost-effective, occur earlier, or are more frequently measured, are sometimes used to replace costly, late, or rare true endpoints. Regulatory authorities typically require thorough evaluation and validation to accept these surrogate endpoints as reliable substitutes. To this end, the meta-analytic framework is considered a very viable approac
This study aims to identify important market characteristics that affect international market establishments in the IT consulting industry. A qualitative case study has been conducted at an IT consulting firm, where Osterwalder's Business Model Canvas has been used as a tool to identify and compare market characteristics to existing theory regarding internationalisation in the Knowledge-Intens
