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This essay has three main aims. The first one is to give an overview of some hundred years of European intellectual history, bringing out new aspects of the classical thinkers. The analysis of the four philosophers Thomas Hobbes, John Locke, David Hume and Charles de Montesquieu aims at illustrating a general historical process, viz. the emergence of the modern view of man in Europe. After Hobbes,

Knowledge work is often portrayed as hidden or ambiguous: an ambiguous product is sold, ambiguous results are delivered, and work processes are ambiguous. This in turn affects the type of management expected in knowledge-intensive organisations, where emphasis is on managing people rather than work. In this study, the organisation of knowledge work is discussed and problematized through analysis o

The research field of the thesis is clinical adult psychiatry and it focuses on the treatment of patients with autism spectrum disorders. Before the publication of DSM-IV (Diagnostic and Statistical Manual of Mental Disorders) in 1994 intellectually high-functioning patients with autism have not been included in diagnostic manuals and received appropriate treatment in adult psychiatry. In recent y

This thesis concentrates on the development, synthesis and evaluation of supramolecular systems, assembled from its components by means of hydrogen bonding, using the self-complementary 2-pyridone motif. The thesis is divided in two parts. 1) Supramolecular catalysis: Substrate selectivity is imposed on a derivative of Jacobsen's catalyst, an Mn(salen) complex with 2-quinolone hydrogen-bonding gr

The aim of this work was to develop, implement and evaluate an independent system with which to calculate the absorbed dose, delivered by high-energy X-ray beams, to the prescription point and the depth of dose maximum. The introduction of such a system in the clinical routine may help ensure high-quality treatment and avoidance of errors which may jeopardise the clinical outcome of the treatment

The ongoing increase in atmospheric greenhouse gas concentrations causes an increase in the global mean air temperature. One important moderator of the atmospheric carbon dioxide (CO2) concentration is the gas exchange between the atmosphere and the biosphere; photosynthesis extracts and respiration releases CO2, resulting in a net exchange. A variety of methods are used to improve our understandi

This study explores the role of transcriptional regulation important in the development of L-DOPA-induced dyskinesia in a rat model of Parkinson’s disease. In patients with Parkinson’s disease, dyskinesia is one of the most difficult complications of the DA-replacement therapy by L-DOPA. The underlying mechanisms are still unknown, but a role of abnormal striatal plasticity has been proposed. The

Simulation of coupled dynamical systems, where the subsystems are bundled with their own internal solver, is important in industry. This is due to that in many cases, with complex systems, this is the only viable option. In this setting, the dynamics of each system is hidden and information between subsystems is exchanged through sampled inputs and outputs, a weakly coupled system. While a new ind

The results presented in this thesis can be divided into four areas of investigation: Investigation of the effect of new volume-crank angle relations on engine emissions, power and efficiency; investigation of nitrogen oxides effect on auto ignition and knock in SI engines; investigation of premixed SI and HCCI engine operation with the alternative fuels hydrogen and reformed methanol gas (RMG); s

Deprived of human rights, more than half of all people with disabilities in developing countries live in extreme poverty. Although considered a prerequisite for equalization of opportunities, about nine out of ten of those who need assistive technologies do not have access to them. Little is known about the socioeconomic benefits of using assistive technology in low-income countries that can infor

Policies based upon Extended Producer Responsibility (EPR) aim to reduce the environmental impacts of products across their entire life cycle. The intent is to induce design changes in products and thus reduce impacts at source. This, by provision of incentives to producers through an extension of responsibility. Since the early 1990s, a number of countries have incorporated the concept of EPR int

The aim of this thesis is to analyse the status of new stained glass from 1851-1955. The point of departure is that, despite stained glass having been part of the ?uvre of many well-known artists, it is often not included in the general history of art. One primary methodological approach is to examine the issue of status emerging from notions of the media-specific qualities of stained glass. The

Lean has become a popular organization model during the late 21st century, and it is widely spread through healthcare with high expectations of improvement and reorganization. The implementation of a certain policy is in the literature seen as a crucial step in policy realization. To better understand Lean and its adaptation to healthcare, this study examines how Lean is being implemented into Swe

The thesis sets out to investigate the research question “Does subject certification affect student achievement in mathematics?” By using data from an international large-scale assessment of student skills, Trends in International Mathematics and Science Study (TIMSS), the thesis uses student achievement scores in mathematics as the dependent variable in a series of multiple linear regression mode