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Simulations of Transport Phenomena and Porous Structures Using Dissipative Particle Dynamics

The topic of this work is simulations of porous materials and transport phenomena at a mesoscopic length scale, i.e., a length scale larger than an individual atom but smaller than the continuum. The porous material studied is a membrane used in fuel cells. Mass transfer has also been studied in the membrane. Heat and mass transfer has been studied in parallel plate channels, first in saturated ch

Follow-up of children with congenital clubfoot. Development of a new evaluation instrument.

Clubfoot is a congenital disorder, affecting about one of 1000 children. Treatment consists of initial correction of the deformity, followed by prolonged orthosis treatment to maintain the correction obtained. There are several different treatment options. Outcome studies, using reliable and valid instruments are rare. In this thesis an assessment instrument, Clubfoot Assessment Protocol (CAP) wa

Som vem som helst : Kön, funktionalitet och idrottande kroppar

The main aim of this thesis is to explore young women’s lived experience of the body, which, on one hand, is viewed as deviant – the disabled body – and, on the other hand, is viewed as accomplished – the sporting body. The questions posed in the thesis are the following: how do the young women handle the two subject positions that emerge as a result of the perception of them as respectively devia

Järnålderns Skåne : samhälle, centra och regioner

The first purpose of this dissertation is to describe and discuss the development of the Iron Age society in Scania. The second purpose is to discuss the relations between Scania and the neighbouring areas. The Iron Age society was hierarchical and ruled by different types of leaders, usually cheiftains or kings. To maintain and develop the social system different social groups acted in society.

Towards Quantitative Diagnostics using Short-Pulse Laser Techniques

Laser based diagnostic tools have had an exploding impact on fundamental as well as applied research in a number of disciplines, such as biomedicine, physical chemistry etc over the last decades. Whereas fundamental research often investigate phenomena in extreme conditions, applied research aims at performing in-situ measurements, in order to understand the many aspects and entangled phenomena th

Aspects of Morphological and Stylistic Variation of the Verb in Erotokritos

The aim of the present study is to examine the polytypia (morphological variation) and semantic differentiations of the verb in Vitsentzos Kornaros' Erotokritos, to understand how these shape poetic style. We examine the stems and the endings in the imperfective active forms. Moreover, we investigate the augmented forms because at an early stage we found that Kornaros employs a degree of poetic li

Streptococcal virulence and the coagulation system.

This thesis explores streptococcal virulence from both mechanistic and evolutionary perspectives, where the mechanistic studies focus on interactions with the human coagulation system. We describe interactions between streptococcal surface proteins and components of the intrinsic pathway of coagulation and the kallikrein-kinin system in human plasma, as well as to how these surface proteins are pr

Higher-Order Regularization in Computer Vision

At the core of many computer vision models lies the minimization of an objective function consisting of a sum of functions with few arguments. The order of the objective function is defined as the highest number of arguments of any summand. To reduce ambiguity and noise in the solution, regularization terms are included into the objective function, enforcing different properties of the solution. T

Health-related Quality of Life in Head and Neck Cancer. A Five-year Prospective Multicenter Study

The aim of this prospective longitudinal multicenter study was to evaluate the health-related quality of life (HRQL) in patients with head and neck cancer at diagnosis, after one and five years in relation to tumour location, stage, sub site, treatment modality, gender and age. The first part of the study, lasting for one year, consisted of 357 patients (mean age 63 years; 72% males) that were in

Cell and Gene Therapy for Parkinson's Disease: Therapeutic Effect and Modulation of Dyskinesias in the 6-OHDA Rat Model

The main pathological feature in Parkinson's disease is the progressive loss of dopamine neurons in the midbrain, which in turn leads to the appearance of motor deficits such as akinesia/bradykinesia (loss/slowness of movements), rigidity, postural imbalance and tremor. To this day, there is no cure for the disease, but there are medications to relieve the symptoms. The gold standard medication is

Maktutövning ur ett organisations- och genusperspektiv. En studie vid tre vårdavdelningar

The primary aim of the present thesis is to increase understandig of the relationship between organisational structure, gender and power. Understanding of this relationship requires a closeness to the individual being studied as well to the content and consequences of that individuals´actions. The empirical object of study is a group of professional women at a somatic clinic. The problem investiga

Lung mechanics in the aging lung and in acute lung injury. Studies based on sinusoidal flow modulation.

Knowledge about lung mechanics is of interest in intensive care to adjust mechanical ventilation and in the lung laboratory for diagnostics and evaluation of patients with various kinds of respiratory diseases. In mechanical ventilation a single inspiratory elastic pressure-volume (Pel/V) curve is difficult to interpret due to continuing re-expansion of collapsed lung units over a large pressure

Genetic modeling of the Hippo pathway in hematopoietic stem cells

Hematopoiesis is the process of blood formation from a limited pool of hematopoietic stem cells (HSCs). These rare stem cells can both self-renew to maintain the HSC pool, and differentiate to continuously replenish lost blood cells. The mechanisms of HSC regulation are not fully known. The aim of this thesis was to study the role of the Hippo signaling pathway in HSCs. The Hippo pathway is a newl

På AI-teknikens axlar : Om kunskapssociologin och stark artificiell intelligens

This dissertation is concerned with Sociology’s stance in the debate on Strong Artificial Intelligence, i.e. such AI that is able to shape new knowledge without human interference. There is a need for sociologists to realize the difference between two approaches to constructing AI systems: Symbolic AI (or Classic AI) and Distributed AI – DAI. Sociological literature shows a largely critical attitu

Improved Interpretation of Myocardial Perfusion Images by Artificial Neural Networks

Correct interpretation of medical imaging is based upon the interpreter’s experience and image quality. Depending on the report given the clinician decides how to use the result of the study. For many years a large number of image technologies including myocardial perfusion scintigraphy (MPS) have been acquired in digital format and the development of the imaging modalities are progressing rapidly

Different Images of Science - A study of how science is constituted in exhibitions

Within the science and technology centre (STC) movement there exists explicit aims and ambitions to enhance visitors’ interest in and knowledge about science. Meanwhile, several researches question the choice of the scientific content in exhibitions when arguing that a too unproblematic view of science commonly is presented. But what images and aspects of science are visitors actually confronted w

Methods to Improve and Evaluate Spatial Data Infrastructures

This thesis mainly focuses on methods for improving and evaluating Spatial Data Infrastructures (SDIs). The aim has been threefold: to develop a framework for the management and evaluation of an SDI, to improve the accessibility of spatial data in an SDI, and to improve the cartography in view services in an SDI. Spatial Data Infrastructure has been identified as an umbrella covering spatial data

Setting the Marketing Scene: Reality Production in Everyday Marketing Work

The aim of this thesis is to offer a contribution to the understanding of marketing work. In orthodox, mainstream marketing management literature, the work of marketing is commonly depicted as a fairly straightforward practice, technical in character, neutral in terms of social values and ideologies, operating within an objective and pre-given world. A counter picture to this idealised view of mar

Physical Aspects of Thermotherapy - A study of heat transport with a view to treatment optimisation

Local treatment with the aim to destruct tissue by heating (thermotherapy) may in some cases be an alternative or complement to surgical methods, and has gained increased interest during the last decade. The major advantage of these, often minimally-invasive methods, is that the disease can be controlled with reduced treatment trauma and complications. The extent of thermal damage is a complex fun

Numerical Modelling and Analysis of Orthogonal Metal Cutting

Most components in use in our society have undergone a machining process at some stage within its manufacturing cycle. As a result, the economics of the machining process plays an important role in the manufacturing costs. There are several reasons for developing a rational approach to material removal, such as improving cutting techniques, producing products with enhanced precision, and increasin