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The aim of the thesis is to contribute to knowledge of (1) psychosocial illness in the population, (2) the prevalence and nature of psychosocial illness encountered in primary health care, and (3) encountered among persons with long-term illness. The data collected include the results of a questionnaire given to a population-based sample of 13 000 persons (20-84 years), a questionnaire given to ge
This thesis concerns clean and adsorbate covered metal surfaces and surface alloys. These systems have been studied using theoretical and experimental methods. In the first part of the thesis, the different techniques that have been utilized in this work are presented, and the included publications are summarized. The second part of the thesis consists of seven original publications. In the first
The serotonergic vascular control was investigated by in vitro pharmacology in the human uterine and umbilical arteries. The localisation of immunoreactive (IR) neuropeptide Y (NPY) and the influence of NPY on the adrenergic vascular effects in the human uterine artery were also studied. NPY-IR nerve fibres were observed predominantly at the media-adventitial border of the uterine artery. About 50
New measurements of the elements Ba, Fe, Ga, In and Ru are reported. The analysis of barium contains new wavelengths, improved energy level values and new values of the ionization limit in both Ba I and Ba II. Oscillator strengths and radiative lifetimes in Fe II, as a part of the FERRUM project, are reported. The gallium analysis includes new wavelengths, ab initio calculated oscillator st
Purpose: To study dark adaptation in patients with symptomatic carotid artery disease or polycythemia before and after treatment. This necessitated determinations of pupillary changes as such may influence the findings. To determine whether changes in the retinal blood flow in light and darkness occur in healthy humans. Methods: Repeated automatic dark adaptometry was recorded monocularly in 21 c
Telomeres are specialized complexes of DNA and proteins that cap and confer stability to the ends of eukaryotic chromosomes. The telomeric DNA of most eukaryotes is composed of tandemly arranged short repeats. Within the budding yeasts these repeats are diverged in length as well as in nucleotide composition. However, they contain a sequence resembling the consensus binding sequence of the major t
It is a necessity of life to make proteins, and it is an equal necessity to degrade those proteins, to eliminate dysfunctional proteins, and leave room for new ones. The processes of protein synthesis and degradation into peptides - proteolysis - have attracted a great interest during the last decades. The eye contains several highly specialized tissues, in which the protein turnover is of vital
The gram-positive bacterium Enterococcus faecalis is a commensal organism, often found in the gut of humans and other animals. It can cause opportunistic disease and it frequently causes nosocomial infections. Treatment of such infections is often impaired by this organisms broad intrinsic and acquired resistance to antibiotics. E. faecalis uses homo-lactic fermentation for energy pr
The intention of this work was to establish alternative purification methods to obtain highly purified caveolae from various tissues. In order to isolate caveolae, sufficiently pure plasma membranes are needed. A method is presented for the isolation of plasma membranes from lung tissue using a combination of conventional polyethylene glycol/dextran two-phase partitioning and affinity partitioning
Helicobacter pylori is a gastric pathogen which cause chronic type B gastritis and peptic ulcer disease. H. pylori produces virulence factors such as urease, vacuolating cytotoxin VacA, cag pathogenicity island-associated proteins, flagella and adhesins. These proteins interact with several host cell molecules such as sialylated cell surface glycoproteins, some of glycolipids and mucins. Glycosami
Artificial, amfiphilic, and biomimetic receptors soluble in water were synthesized via attaching polar amino acids to hydrophobic back-bones possessing a surface suitable for hydrophobic interactions. The hydrophobic back-bones chosen in this thesis were anthracene and dibenzobarrelene structures. A route to an efficient synthesis of a dibenzobarrelene backbone with two sets of orthogonal reactivi
In fantasy literature, the setting is as important to the story as are characters and plot; but although many fantasy scholars have pointed this out, there is very little criticism that explores the role of the setting in fantasy. The aim of this study is to use a topofocal (place-focused) perspective to examine four aspects of the fantasy setting, including the way in which settings function in t
In this thesis, electron transport in mesoscopic semiconductor nanostructures, in particular so-called electron billiards or quantum dots, is studied. The thesis can be divided into two areas: the linear response regime of transport, and the nonlinear response regime of transport. The classical and quantum mechanical electron dynamics are studied for triangular and square-shaped electron billiard
This study is based on dialogic readings of two of John Cowper Powys´s major novels, A Glastonbury Romance and Porius. The aim of this thesis is to demonstrate the interrelationship in the examined texts between the chain of narrative displacements and the frequent changes of voice and genre. Powys´s cornucopian writing with its wide employment of characteristics from various genres
The root vole (Microtus oeconomus) is a rodent with Holarctic distribution. In fact, it is the only Microtus vole found in both Eurasia and North America. Phylogeographic analyses of the root vole from across its distribution range were performed using mitochondrial and Y chromosome DNA sequences. Mitochondrial cytochrome b gene data demonstrate that the root vole is divided i
Phage display technology is a biotechnological tool that can be used to obtain molecules/reagents able to discriminate between target molecules. Reagents with such features can be used in diverse settings like biological chemistry, diagnostics and in therapeutic applications. Phage display technology is based on the use of recombinant DNA technology, bacteria and a special kind of bacterial virus,
The regulation of the exocrine pancreas has been under thorough investigation for many decades. In rats, cholecystokinin (CCK) is considered to be the major gut hormone stimulating the pancreas to releasing the digestive enzymes. CCK acts directly via CCK-A receptors in the pancreas, or through receptors located on the vagal afferents and stimulating the secretion via the cholinergic vagal efferen
Elastic scattering and the Lorenz-Mie (LM) theory in particular is used for the characterization of sub-micron- and micron-sized droplets of organic fuels in sprays and aerosols. Calculations on the Lorenz- Mie theory show that backward-sideward scattered visible radiation can be used for unambiguous detection of ensembles of homogeneous droplets of organic substances with diameters around 1 micro
The fermentative performance of bacteria, yeasts, and filamentous fungi was investigated in a pentose (xylose)-rich lignocellulosic hydrolyzate. The filamentous fungus Fusarium oxysporum and the xylose-fermenting yeast Pichia stipitis were found to be very sensitive to the inhibiting hydrolyzate. Recombinant xylose-utilizing Saccharomyces cerevisiae showed very poor ethanol formation from xylose;
The growth of social science and sociology during modernity has always been characterized by a will to create predictability for human actions, under the modern conditions of liberty seen as contingent, unpredictable and unstable. To gain systematic knowledge became a way to solve, counteract or radicalize tensions in society, and thus outweighing the risks of contingency. Furthermore, this develo
