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Traveller information designed to fulfil needs and expectations of individual travellers is a key factor in improving access for older people and people with disabilities to public transport. The overall aim of this thesis is to contribute to the knowledge of user and provider perspectives on the provision of traveller information for older people and people with disabilities in public transport w

Stroke is an acute neurological condition and the leading cause of disability in adult humans. Treatments for efficient recovery are not available. The most common form of stroke results from the occlusion of the middle cerebral artery, which causes loss of brain parenchyma and many types of neurons as well as astrocytes and oligodendrocytes. Neural stem cells (NSCs) could potentially be used to d

B-cells are an essential part of our adaptive immune system. A network of transcription factors together with external signals facilitate the gradual developmental progression from progenitor cells towards the B-cell fate. Several key factors participating in this network have been identified. Among these are the transcription factors E2A, HEB, EBF1 and FOXO1 as well as the IL7 signaling cascade.

In this thesis, an inverse source reconstruction method with great potential in radome diagnostics is presented. A radome is a cover that encloses an antenna in order to protect it from environmental influences. Radome diagnostics are acquired in the design process, the delivery control, and in performance verification of repaired and newly developed radomes. A measured near or far field may indic

In human cells there are usually two copies of each chromosome, but in cancer cells abnormalities could exist. The differences consist of segments of chromosomes with an altered number of copies. There can be deletions as well as amplifications and the lengths of the segments can also vary. Localising the deviant regions is of great importance for increasing the knowledge of the disease. In this t

Parkinsons disease (PD) is a neurodegenerative disorder where dopaminergic neurons of the substantia nigra (SNc) in the mesencephalon are progressively eliminated. The ensuing loss of dopaminergic innervation of the basal ganglia manifests itself as severe motor deficits in PD patients. Clinical trials have shown that cell replacement therapy, where dopaminergic neuroblasts derived from fetal vent

It has been shown that the present interglacial has been climatically dynamic with both rapid and severe climatic fluctuations. The spatial and temporal differences of these changes are however not fully resolved. The aim of this thesis is to present a detail high resolution record of past climate changes from the central South Atlantic. Peat and lacustrine sediment sequences were retrieved from

Infectious diseases constitute a major global health problem. The presenting clinical picture results from a mixture of direct toxic actions by the microbiological agent and of the immune response mounted by the host. There is often a rapid onset, which may constitute a diagnostic and therapeutic challenge, whereas in other cases an extensive investigation over a long time period can fail to ident

Arctic ecosystems represent an important component in the global terrestrial exchange of greenhouse gases and energy with the atmosphere. In the changing climate, which is most pronounced in the Arctic, the possible scenarios of greenhouse gas exchange response should be seriously considered in predictive climate modelling efforts. As a prerequisite for this, detailed studies of key processes affe

The theory of stochastic time-frequency analysis of non-stationary random processes has mostly been developed for processes in continuous time. In practice however, random processes are observed, processed, and interpreted at a finite set of time points. For processes in continuous time, the ambiguity domain has interesting properties which makes it particularly useful. One such property is that t

Avian eyes are big both in relative and absolute terms, thus the importance of vision to birds is obvious. Even though the general eye plan is rather conservative throughout the group, there is a great variation in visual capabilities. In this thesis I present four studies on different aspects of spatial vision in parrots, procellariiform seabirds and birds of prey. In Paper I we studied retinal g

The solution properties of dilute aqueous solutions of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) triblock copolymers and their interaction with surfactants have been investigated using static and dynamic light scattering, combined with small angle X-ray scattering, calorimetry and nuclear magnetic resonance techniques. In aqueous solution, the triblock copolyme

The events associated with axonal injury in the peripheral nervous system (PNS) have been described in detail. However, the molecular mechanisms underlying the regenerative response, or neuronal cell death, following axonal injury are poorly understood. This thesis concerns one such molecular mechanism, JNK-mediated c-Jun activation, in peripheral sensory and sympathetic neurons. By immunohistoche

The nature of future climate change will depend on anthropogenic emissions of CO2, as well as climate- and CO2-mediated feedbacks through carbon (C) cycling in both terrestrial ecosystems and oceans. Terrestrial ecosystems remove presently about 25% of the anthropogenic CO2 fossil-fuel and land-use change emissions, but to attribute which mechanisms cause this uptake, and the key regions where it

Rapid heat transfer methods such as jet impingement and infrared radiation can be used to speed up thermal processing in the food industry. The heating rate affects important food characteristics, such as colour. Jet impingement consists of directed jets of air with a high velocity that impinge on the food surface, which reduces the velocity boundary layer between the air and surface and gives a f

If Luke’s first audience understood the Gospel as a biography, what would their experience of the text have been? This book invites the reader to accompany the first readers or hearers of Luke’s Gospel and to experience the narrative about the life of Jesus alongside them. It utilises Wolfgang Iser’s theory about reading and readers and focuses on gaps and vacancies in the text. The most important

Apoptosis is a kind of death that is best described as cellular suicide and it is important for normal tissue homeostasis. The process can be induced by a number of different stimuli and the dying cell goes through a defined pathway terminating in typical biochemical and morphological alterations of the cell. With my studies I wanted to investigate the role of the polyamines in the regulation of a

Mobile in situ gamma spectrometry is an important instrument in the emergency preparedness for nuclear accidents. This work contributes through the development of strategies and analysis methods for two applications: an on-line search for gamma-emitting orphan sources and on-line estimation of the depth distribution of 137Cs. A strategy and analysis method dedicated to the detection of orphan sour

Denna uppsats behandlar frågan om mediebilden och tidigare forskning rörande kvinnor och politisk identitet i Afghanistan. Hur presentationen av kvinnorna ser ut och hur deras situation och positionering görs av kvinnor i Afghanistan och hur detta beskrivs i tidningen Dagens Nyheter. Dagens Nyheter är den svenska dagstidning som vi valt ut då vi anser den ha hög validitet och stor läsarkrets. Geno