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Activating signaling mutations are common in acute leukemia with KMT2A (previously MLL) rearrangements (KMT2A-R). These mutations are often subclonal and their biological impact remains unclear. Using a retroviral acute myeloid mouse leukemia model, we demonstrate that FLT3 ITD, FLT3 N676K, and NRAS G12D accelerate KMT2A-MLLT3 leukemia onset. Further, also subclonal FLT3 N676K mutations accelerate

The identification of carotid atheromatous plaques associated to a higher neurologic risk may be important in therapeutic decision making for asymptomatic patients and symptomatic patients with 50%-70% stenosis. The introduction of high-definition ultrasonography (HDU) and computer-assisted image analysis provides the possibility of a standard, objective and detailed characterization of the struct

The extraction of spectral information in the inversion process of time-domain (TD) induced polarization (IP) data is changing the use of the TDIP method. Data interpretation is evolving from a qualitative description of the subsurface, able only to discriminate the presence of contrasts in chargeability parameters, towards a quantitative analysis of the investigated media, which allows for detail

Purpose The purpose of this study is to better understand online anonymity in the global file-sharing community in the context of social norms and copyright law. The study describes the respondents in terms of use of Virtual Private Networks (VPNs) or similar services with respect to age, gender, geographical location, as well as analysing the correlation with file-sharing frequencies. Design/me

The halotolerant bacterial strain BU-4, isolated from a hypersaline environment, was identified as an exopolysaccharide (EPS) producer. Pretreatment liquids of steam-exploded quinoa stalks and enzymatic hydrolysates of Curupaú sawdust were evaluated as carbon sources for EPS production with the BU-4 strain, and the produced EPS was characterized using FTIR, TGA, and SEM. Cultivation was performed

Abstract of chapter 1 For n >= 2 the number of mixing n-step subshifts of finite type (sft) over the alphabet {0, 1} is proven to be at least 15/16 times the number of transitive n-step sfts. A conjecture assumes the latter to be at least 2^(3*2^(n-1)-n). Abstract of chapter 2 The alternating colouring function is defined. Strings over the alphabet {0, 1} are divided in colourable and non-colouraImagine an of characters A and B. Such can be thought of as a paper strip with As and Bs written on it, one end of which one holds in the hand while the other stretches over the horizon without ever ending. Or as a calculator that displays a new character each second. Or as a printer with an infinite amount of paper and ink that unfortunately only prints As and Bs. In contrast to infinite strings

Växter behöver ljus. Ljuset omvandlas genom fotosyntesen till kemisk energi som kan lagras i växten. Mer ljus ger således mer energi men bara upp till en viss gräns. När växten inte längre kan hantera mängden ljus som den utsätts för kommer flaskhalsar i processen orsaka att högenergetiska tillstånd blir mer långlivade. Dessa reaktiva ämnen kan då orsaka skada på närliggande komponenter, vilket kaPlants and algae need light to drive the photosynthetic machinery. An excess of light will, however, result in damage to the photosynthetic machinery and to the rest of the organism. The surplus of energy, when exposed to light stress is converted into less harmful heat energy through a process called non-photochemical quenching. This quenching is partly dependent on the xanthophyll pool located i

Elspeth Lee - February 8th, 2022 Centre for Space and Habitability, University of Bern, Switzerland   Nikolai Piskunov - February 22nd, 2022 Department of Physics and Astronomy, Uppsala University, Sweden   Geneviève Parmentier - March 1st, 2022 Astronomisches Rechen-Institute, Zentrum für Astronomie, University of Heidelberg, Germany   Else Starkenburg - March 8th, 2022 Faculty of Science and Eng

https://www.astro.lu.se/meetings/kallen-seminars-young-astronomers/speakers-vt-2022 - 2026-05-17

Acousmatic Concerts at IAC PROGRAMME 22–26 APRIL 2026 IAC.LU.SE Scan the QR code for detailed programme and artist bios! Wednesday, 22 April 17:00 & 19:00 ELIDE SULSENTI: Tundo, Sdraulig (Black Room) Performance with cello and headphones. Limited to 15 listeners per concert! Matteo Tundo – Cuoio (for cello and electronics) Charlie Sdraulig – Arc (for cello and electronics) Total duration: ca. 30 m

https://www.iac.lu.se/sites/iac.lu.se/files/2026-05/Intonal_2026_broschyr_A5_FINAL.pdf - 2026-05-19

In order to reduce the net climate impact of concrete production, it is necessary for the industry to undertake several actions. Among these is to include fly ash and slag as supplementary cementitious materials. Accordingly, this project has studied concrete containing low-calcium fly ash or ground-granulated blast-furnace slag. In incorporating fly ash or slag as supplementary material, the ceme

The current situation of Uyghurs in the Xinjiang Uyghur Autonomous Region (XUAR) is considered by many as one of the most pressing human rights violations of the last few decades. The Uyghurs, being an ethnic minority in China, are voiceless under the current political leadership, which suppresses anything deviating from the official course set up by the Party leaders in Beijing. The legal guarant