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Many ectothermic species are currently expanding their distributions polewards due to anthropogenic global warming. Molecular genetic mechanisms facilitating range expansion under these conditions are largely unknown, but understanding these could help mitigate expanding pests and disease vectors, or help explain why some species fail to track changing climates. Here, using RNA-seq data, we examin
Popular Abstract in Swedish Hawaiianernas liv och historia har dokumenterats allt sedan första kontakten med västerländska äventyrsresanden i slutet av 1700-talet. I samband med amerikanska missionärers ankomst år 1820 introducerade och etablerade dessa missionärer en puritansk lära och kunskapsförmedling via det skrivna ordet. Mötena mellan de olika kulturerna har beskrivits som fredliga. Dock haThe life and history of the Hawaiians has been documented ever since the contact with Western adventurers at the end of the 18th century. In connection with the arrival of American missionaries in 1820, these missionaries introduced and established a puritanical doctrine and method of communicating knowledge by way of the written word. The encounters between the different cultures have been descri
Popular Abstract in Swedish Proteiner är nödvändiga beståndsdelar i en levande cell. Dels bygger de upp viktiga strukturer och dels katalyserar de kemiska reaktioner. Proteiner kodas av gener. Varje protein motsvaras av en gen. Vägen från gen till protein är densamma i alla organismer på jorden. Först transkriberas en gen till en molekyl kallad mRNA (budbärar-RNA, eng. messenger RNA). Detta mRNA aDegradation of mRNA is a controlled process which is as important for gene regulation as the synthesis of mRNA. This thesis focuses on mechanisms of mRNA stability and degradation in Bacillus subtilis, the model of Gram-positive bacteria. The aprE mRNA, encoding an exported protease named subtilisin, is extremely stable with a half-life of more than 25 minutes. Average mRNA half-lives in B. subtil
Popular Abstract in Swedish Avhandlingens syfte är att söka kunskap om vilka faktorer som bidrar till uppfostringsanstaltens framgång som social institution och dess ständiga misslyckande som behandlingsorganisation. Jag försöker förstå varför organisationer som §12-hem och särskilda ungdomshem finns och vilken betydelse de har i vårt samhälle. Svaret på den frågan söker jag på tre sätt: genom attThe aim of the present study is to find the factors and conditions that generate the success of the reformatory as a social institution and, at the same time, its well-known failure as a treatment organization. I try to understand why organizations like the reformatory exist and what meaning they have in our society. I seek answers by exploring the birth of the reformatory in a historical perspect
The formation of planetary cores must proceed rapidly in order for the giant planets to accrete their gaseous envelopes before the dissipation of the protoplanetary gas disc (less than or similar to 3 Myr). In orbits beyond 10 AU, direct accumulation of planetesimals by the cores is too slow. Fragments of planetesimals could be accreted faster, but planetesimals are likely too large for fragmentat
Three studies investigated decision makers' memory representations of choice alternatives in most important real-life decisions. In Study 1, each participant recalled the most important decision that she or he had ever made and rated to what degree a number of characteristics could describe the decisions. In Study 2, the participants were asked to think about an important decision that they had ma
Background: Scientific reviewing is a voluntary process to determine if a manuscript deserves publication. REVIEW means: Responsibly Evaluate, Verify and Improve the manuscript, Educate the authors and editors, and Weigh your expert opinion against the submitted work. Provide your review in a respectful, unbiased and timely manner. Review Methods: Make sure editors know about your willingness to r
Wireless sensor networks are composed of a large number of sensor nodes with limited energy resources. Once deployed, the sensor nodes are usually inaccessible to the user, and thus replacement of the energy resource is not feasible. Hence, energy efficiency is a key design issue that needs to be enhanced in order to improve the life span of the entire network. Several routing protocols have been
BACKGROUND: There are limited reports in literature studying the impact of rod diameter and stiffness on the degree of deformity correction in patients with AIS. AIMS: The aims of this study were to evaluate the 3-dimentional deformity correction achieved by segmental pedicle screw fixation in patients with adolescent idiopathic scoliosis, and to find out if learning or the change to stiffer rods
OBJECTIVE :Patients with symptoms and signs compatible with psoriatic arthritis (PsA), with or without psoriasis, have been documented in the Swedish Early Psoriatic Arthritis (SwePsA) register. Our aim was to find markers for disease progression and to evaluate treatments for PsA using these data. METHODS: Patients referred to rheumatology outpatient clinics within 2 years of onset were assessed
Many cell functions rely on the ability of microtubules to self-organize as complex networks. In plants, cortical microtubules are essential to determine cell shape as they guide the deposition of cellulose microfibrils, and thus control mechanical anisotropy in the cell wall. Here we analyze how, in turn, cell shape may influence microtubule behavior. Using a computational model of microtubules e
Increased blood lipid levels are heritable risk factors of cardiovascular disease with varied prevalence worldwide owing to different dietary patterns and medication use1. Despite advances in prevention and treatment, in particular through reducing low-density lipoprotein cholesterol levels2, heart disease remains the leading cause of death worldwide3. Genome-wideassociation studies (GWAS) of bloo
Actual land evapotranspiration (ET) is a key component of the global hydrological cycle and an essential variable determining the evolution of hydrological extreme events under different climate change scenarios. However, recently available ET products show persistent uncertainties that are impeding a precise attribution of human-induced climate change. Here, we aim at comparing a range of indepen
This research report is a compilation of essays written by guest researchers from Central Asia who spent four to twelve months at the Department of Sociology of Law, Lund University, and conducted research on various topics pertaining to legal cultures, governance and business environments in Central Asia. These guest research stays (secondments) took place in the framework of the EU-funded projec
Avhandlingen består av tre oberoende kapitel som alla är empiriska studier av forskare och den roll som olika typer av rörlighet spelar för att forma forskarnas vetenskapliga produktion och karriär.Kapitel 1 studerar effekterna av avregleringen av svensk arbetsmigration, 2008, på publiceringsproduktiviteten hos akademiker verksamma i Sverige. Reformen ledde till en kraftig ökning av antalet asiatiThe thesis consists of three independent chapters. The chapters are all empirical studies of scientists and the role that different types of mobility play in shaping researchers' scientific output and careers.Chapter 1, uses the liberalization of Swedish work migration, in 2008, to study the effect of immigration on the publishing productivity of incumbent academics in Sweden. The reform led to a
Objective. To compare the rate of occurrence of comorbidities, including severe infections, in a population-based cohort of patients with biopsy-proven giant cell arteritis (GCA) with a reference population in Southern Sweden. Methods. The study included a population-based cohort of biopsy-proven GCA cases diagnosed between 1998 and 2010 from the Skane region in Southern Sweden (population: 1.2 mi
Planetary migration is a major challenge for planet-formation theories. The speed of type-I migration is proportional to the mass of a protoplanet, while the final decade of growth of a pebble-accreting planetary core takes place at a rate that scales with the mass to the two-thirds power. This results in planetary growth tracks (i.e., the evolution of the mass of a protoplanet versus its distanc
The compressibility of a protein relates to its stability, flexibility, and hydrophobic interactions, but the measurement, interpretation, and computation of this important thermodynamic parameter present technical and conceptual challenges. Here, we present a theoretical analysis of protein compressibility and apply it to molecular dynamics simulations of four globular proteins. Using additively
There are two levels to this thesis, the examination of the particular case and the exposition of the general approach. The case the thesis deals with is Louisiana’s coastal land-loss crisis and what can and should be done about it. I examine the current approach to coastal protection and restoration in the state of Louisiana, drawing on different economic theories of sustainable development and c
