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The direct effects of UV-B radiation on Betula pubescens litter decomposing at four European field sites

A co-ordinated series of field experiments were conducted to consider the effects of elevated UV-B radiation applied directly to decomposing plant litter. Betula pubescens was decomposed under ambient and elevated UV-B (simulating a 15% ozone depletion) using outdoor irradiation facilities at Adventdalen, Norway (78° N), Abisko, Sweden (68° N), Amsterdam, The Netherlands (52° N,) and Patras, Greec

An Escherichia coli Mutant Quinol:Fumarate Reductase Contains an EPR-detectable Semiquinone Stabilized at the Proximal Quinone-binding Site

The EPR and thermodynamic properties of semiquinone (SQ) species stabilized by mammalian succinate:quinone reductase (SQR) in situ in the mitochondrial membrane and in the isolated enzyme have been well documented. The equivalent semiquinones in bacterial membranes have not yet been characterized, either in SQR or quinol:fumarate reductase (QFR) in situ. In this work, we describe an EPR-detectable

Site-selective regulation of platelet-derived growth factor beta receptor tyrosine phosphorylation by T-cell protein tyrosine phosphatase.

The platelet-derived growth factor (PDGF) ß receptor mediates mitogenic and chemotactic signals. Like other tyrosine kinase receptors, the PDGF ß receptor is negatively regulated by protein tyrosine phosphatases (PTPs). To explore whether T-cell PTP (TC-PTP) negatively regulates the PDGF ß receptor, we compared PDGF ß receptor tyrosine phosphorylation in wild-type and TC-PTP knockout (ko) mouse em

Interaction of serum amyloid A with human cystatin Cuidentification of binding sites

Serum amyloid A (SAA) is a multifunctional acute-phase protein whose natural role seems to be participation in many physiologic and pathological processes. Prolonged increased SAA level in a number of chronic inflammatory and neoplastic diseases gives rise to reactive systemic amyloid A amyloidosis, where the N-terminal 76-amino acid residue-long segment of SAA is deposited as amyloid fibrils. Rec

C4b-binding protein: Identification of binding sites and a possible function of the interaction with protein S

Popular Abstract in Swedish Komplementsystemet är ett system bestående av cirka 35 proteiner i blodet och på cellytor, som ingår i kroppens medfödda immunförsvar. Det är ett mycket viktigt men också explosivt system, potentiellt skadligt för kroppens egna celler, som kräver strikt reglering. Denna avhandlings huvudaktör, C4b-bindande protein (C4BP), nedreglerar komplementsystemet. C4BP har en ovanThe subject of this thesis is plasma protein C4b-binding protein (C4BP). C4BP is an important regulator of the classical pathway of the complement system, a cascade-like system comprised of over 35 proteins, which partakes in the defence against micro-organisms and is involved of clearance of immune-complexes and apoptotic cells. C4BP contains two different types of subunits, seven identical alfa-

The seashore – beyond monumentality : The case of Pitted Ware coastal sites in southern Sweden

What is the significance of a place at the seashore? What kind of a sense of place does a place by the seashore constitute in the absence of any kind of monumental structures? Today, it is obvious within the archaeological domain that archaeological material culture is not only functional, but also acts as a metaphor for people’s self-perception. In this article, my assumption is that the differen

The optic tectum of the salmon:site of interaction of neurohormonal photoperiodic and neural visual signals. The GABAergic neuronal system and melatonin receptors.

Popular Abstract in Swedish Melatonin är ett hormon som produceras i, och frisätts från pinealorganet hos ryggradsdjur. Melatoninets viktigaste uppgift är att till hjärnan förmedla signalen om nattens längd, d.v.s vilken årstid det är. Produktionen och frisläppningen sker rytmiskt med den högsta nivån under natten. Melatoninet transporteras ut i kroppen via blodet och binder till särskilda mottaga