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Ionization-site effects on the photofragmentation of chloro- and bromoacetic acid molecules
Simulation of CO2 and Attribution Analysis at Six European Peatland Sites Using the ECOSSE Model
Tumor Targeting Using Affibody Molecules: Interplay of Affinity, Target Expression Level, and Binding Site Composition.
Comparison of Methods to Obtain Force-Field Parameters for Metal Sites
Quantitative assessment of the antiviral potencies of 21 shRNA vectors targeting conserved, including structured, hepatitis B virus sites
Variability in exchange of CO2 across 12 northern peatland and tundra sites
A new route towards colloidal molecules with externally tunable interaction sites.
Humoral immunity targeting site I of antigenic domain 2 of glycoprotein B upon immunization with different cytomegalovirus candidate vaccines.
Identification of Csk tyrosine phosphorylation sites and a tyrosine residue important for kinase domain structure
Redox potentials of the blue copper sites of bilirubin oxidases
Does nest site availability limit the density of hole nesting birds in small woodland patches?
Geometry, Reduction Potential, and Reorganization Energy of the Binuclear CuA Site, Studied by Density Functional Theory
Pollen analysis, chronology and palaeomagnetism of three Late Weichselian sites in southern Sweden
Popular Abstract in Swedish Pollenanalys, kronologi och paleomagnetism på tre senglaciala lokaler i södra Sverige Senglaciala sjösediment (d.v.s. avsatta under slutet av den senaste istiden) från tre bassänger i södra Sverige, Torreberga i Skåne, Farslycke i Blekinge och Bolmen i Småland, har studerats med avseende på pollensammansättning och paleomagnetism. Åldersbestämning och tidsjämförelser b
Identification of a Ser/Thr cluster in the C-terminal domain of the human prostaglandin EP4-R essential for agonist-induced beta-arrestin1 recruitment that differs from the apparent principal phosphorylation site.
hEP4-R (human prostaglandin E2 receptor, subtype EP4) is a Gs-linked heterotrimeric GPCR (G-protein-coupled receptor). It undergoes agonist-induced desensitization and internalization that depend on the presence of its C-terminal domain. Desensitization and internalization of GPCRs are often linked to agonist-induced b-arrestin complex formation, which is stabilized by phosphorylation. Subsequentl
Screening the molecular surface of human anticoagulant protein C: a search for interaction sites
Protein C (PC), a 62 kDa multi-modular zymogen, is activated to an anticoagulant serine protease (activated PC or APC) by thrombin bound to thrombomodulin on the surface of endothelial cells. PC/APC interacts with many proteins and the characterisation of these interactions is not trivial. However, molecular modelling methods help to study these complex biological processes and provide basis for r
Prospects for a regional assessment of forest soil chemistry dynamics in Croatia: Application of the SAFE model to a forested site in the region of Mt. Medvednica
Unusual CO adsorption sites on vanadium oxide-Pd(111) "inverse model catalyst" surfaces
The morphology, structure, and reactivity of vanadium oxide-decorated Pd(111) surfaces, which have been subjected to oxidation and reduction treatments, have been investigated by scanning tunneling microscopy (STM), high-resolution electron energy loss spectroscopy (HREELS), and high-resolution X-ray photoelectron spectroscopy (HR-XPS) with synchrotron radiation combined with ab initio density fun
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The identification of novel, high affinity AQP9 inhibitors in an intracellular binding site
Background: The involvement of aquaporin (AQP) water and small solute channels in the etiology of several diseases, including cancer, neuromyelitis optica and body fluid imbalance disorders, has been suggested previously. Furthermore, results obtained in a mouse model suggested that AQP9 function contributes to hyperglycemia in type-2 diabetes. In addition, the physiological role of several AQP fa
