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TLR4 dependent heparan sulphate-induced pancreatic inflammatory response is IRF3-mediated

Background: Degraded extracellular matrix can stimulate the innate immune system via the Toll-Like Receptor-4 (TLR4). In the pancreas, syndecan-anchored heparan sulphate (HS) on the ductal epithelium can be cleaved off its protein cores by the proteases (trypsin and elastase) and potentially activate TLR4 signalling. Methods: To investigate this signalling event, a low sulphated HS (500 mu g/ml) w

A Textile Exploration

The purpose of this project was at first to explore textiles. It started off by a visit to The Swedish School of Textiles in Borås. I was introduced to the basics of textiles and was shown new textile materials at Smart Textiles. Coming home, I came to the conclusion of doing it my way, with the view of an Industrial Designer. Having prior experience with a similar project I knew that it was imp

LES modelling of spray combustion

Numerisk strömningsmekanik är en kraftfull metod för att förstå flödet och förbränningen som sker i flygplansmotorer och kommer att vara ett avgörande verktyg i övergången från konventionella fossila bränslen till hållbara alternativ. Eftersom mer forskning har skett kring konventionella bränslen bör en simuleringsmetod för alternativa bränslen föregås av en metod som verklighetstroget kan simulerComputational fluid dynamics is a powerful method for understanding the flow and combustion that occurs inside aircraft engines and will be a key tool in the transition from conventional fossil-based fuel to sustainable alternatives. Because conventional fuels have been more widely researched, an attempt at simulating the combustion of alternative fuels should be preceded by the development of a m

‘I will write until I am heard!’ : The Poetic Resistance through Graffiti in China’s Urban Space and Social Media

This thesis investigates the possibility of the mediated city providing a space for resistance in everyday life in a society where free speech channels are strictly controlled. The case studied in this thesis is the phenomenon of a group of fans of a singer who has been banned by the government in mainland China writing graffiti in public urban space on Rehe Road in Nanjing to express their love a

Brevhemligheten - För hemlig ur ett brottsbekämpande perspektiv?

En stor del av narkotikaförsäljningen sker idag via internet och distribueras genom det nationella postflödet där köpare inte sällan får hem försändelserna direkt i sin brevlåda. Mot bakgrund av detta föreslår 2021 års postlagsutredning (SOU 2021:29) ökade möjligheter för de brottsbekämpande myndigheterna att förhindra denna illegala handel. Utredningen föreslår bland annat att ge personal inom poA vast amount of drug sales take place daily via the internet and is distributed through the national postal system, where buyers often receive the items to their mailbox. Considering this, the Swedish Government appointed a new Committee to review the duty of confidentiality in the Postal Services Act (2010:1045) in order to increase opportunities for the law enforcement authorities to prevent th

X-ray Imaging at High Brilliance Sources

Coherent lensless X-ray imaging techniques provide very high-resolution images not limited by optical components. These techniques record diffraction patterns that can be used for retrieving the phase information of the X-rays passing through a sample. To perform high-resolution imaging with coherent imaging techniques, highly coherent X-rays from high brilliance sources, where high-intensity X-ra

Factors affecting the small-scale production of artisan meat : A study of livestock farming in Sweden

This paper examines the structure of livestock farming and of the meat industry in Sweden, focusing on possibilities for small-scale farmers to develop, whether individually or in a group, self-sufficient systems of high quality meat production. The four areas identified as presenting structural difficulties (and in some cases opportunities) to small-scale producers are: i) the centralized structu

Pin Project Part II

The main purpose of the project has been to find the root cause to the failure of a machine component used to secure some vital parts (later on referred to as the pins) of a packing machine. It was already known that the failure had to do with fatigue, but the actual mechanisms were quite unknown. Measurements on the components did not indicate forces that should lead to failure. The components of

Value Investing and The Magic Formula - a method for successful stock investments

With this thesis we want to prove that by using a single formula for picking stocks, Joel Greenblatt’s ‘’Magic Formula’’, it is possible to achieve returns higher than those achieved by a related index. To prove this, we will construct a portfolio, according to “The Magic Formula”, and backtest the portfolio in the Swedish stock market. The test period will be March 1999 to January 2010 and we wil

Comparison of emissions and performance between saturated cyclic oxygenates and aromatics in a heavy-duty diesel engine

Emissions and fuel economy are evaluated for two types of biofuels, namely 2-phenyl ethanol and cyclohexaneethanol. Both are derived from lignin, a form of lignocellulosic biomass. The former and latter oxygenates have an aromatic and aliphatic (i.e. saturated) ring structure, respectively. Two parametric engine sweeps were performed. First, non-EGR operation by means of varying the load via injec

Modeling of Avionics Systems using JGrafchart and TrueTime

The first part of the thesis aims to investigate the applicability of JGrafchart and its associated Model of Computation(MoC) for describing sequential control in aircraft primary power distribution systems. The motivation behind this is the need for better modeling tools and in particular support for separation between nominal control and fault handling. Also, as system complexity increases, bett

Suppressing behaviour related to discomfort induced with a cold pressure task does not influence working memory capacity in a 2-back task.

The study aims to examine the impact of Expressive Suppression (ES), on Working Memory (WM) performance when exposed to mild pain reaction causing physiological activation. Performance measures are obtained to discriminate between three groups having their hands in warm water, cold water, and cold water and implementing ES. As a measure of WM performance, this study used a WM 2-back task intersper

The effects of parking accessibility on work commuting - Considering parking policies as a mobility management tool for Lund

Abstract This thesis addresses the effects of parking accessibility on work commuting and the potential to use parking policies as a tool to support mobility management and enhance sustainable commuting in Lund. The structure rests on two folds: first, it provides a theoretical background on different parking policies and factors influencing work commuting; second, it provides an analysis of Lund

Kraftig

The goal of this project was to design a tool that facilitates the work with and handling of horses in Scandinavia. After reading some literature and making visits to three different horse related businesses the choice were made to look at natural horsemanship. The goal of natural horsemanship is based on mutual respect, trust, communication and understanding. The idea is that you want to give th

Whistleblowing - En komparation av gällande rätt och SOU 2014:31. Innebär lagförslaget ett tillräckligt stärkt skydd?

I dagens informationssamhälle vill medborgarna kunna ta del av så mycket information som möjligt, varför visselblåsning har blivit ett mycket uppmärksammat ämne. Visselblåsare utgör ett viktigt kontrollmoment i samhället som historiskt sett avslöjat uppgifter och skandaler av stort allmänintresse. Denna framställning syftar i en första del till att i ett rättsutvecklingsperspektiv redogöra för de In the age of information people want to get hold of as much information as possible, which is probably why whistleblowing has become such a hot topic. Whistleblowers constitute an important body of control in society which historically has revealed information and scandals of great public interest. The aim of this essay is two-folded. First off the aim is to in a perspective of legislative develo

Models of general community assembly mechanisms simulating the spatial and temporal dynamics of benthic biodiversity

Benthic macroinvertebrates are part of a complex network of interactions. The spatial and temporal scales of the processes that form the basis for these interactions have traditionally restricted their empirical investigation. The first chapter of the manuscript attempts a review of the modelling tools that have been employed for the study of the marine benthos.The implementation of a mechanistic

Cerebrospinal fluid concentrations of extracellular matrix proteins in Alzheimer's disease

Background: Brevican, neurocan, tenascin-C, and tenascin-R are extracellular matrix (ECM) proteins that are mainly expressed in the brain. They play important roles in proliferation and migration of neurons and other cell types in the brain. These ECM proteins may also be involved in various pathologies, including reactive gliosis. Objective: The aim of the study was to investigate if ECM protein

Investigation on bluff-body and swirl stabilized flames near lean blowoff with PIV/PLIF measurements and LES modelling

Lean premixed combustion (LPC) is a promising technology for low-NOx emission, while it increases the risk of blowoff at the same time. Experiments and Large Eddy Simulations (LES) on swirl stratified lean-premixed CH4/air flames were performed to study the differences between the stable and near blowoff flame. The flow fields and instantaneous flame structures were measured by simultaneous Partic

Att leva av produktionsmusik - möjligheter och förutsättningar

Title: To make a living by library music; Opportunities and prerequisites. The purpose of this essay is to investigate how a music producer or composer can achieve placement of his or her music in commercials, TV-shows, computer games, and other media. What is required to make a living by composing and producing music today? This is a qualitative study made by interviewing six persons, who all in