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Background: OSA is a common sleep-breathing disorder linked to increased risk of cardiovascular disease. Intermittent upper airway obstruction and hypoxia, hallmarks of OSA, have been shown in animal models to induce substantial changes to the gut microbiota composition, and subsequent transplantation of fecal matter to other animals induced changes in BP and glucose metabolism. Research Question:

Background Interstitial lung abnormalities (ILA) are incidental findings on chest computed tomography (CT). These patterns can present at an early stage of fibrotic lung disease. Our aim was to estimate the prevalence of ILA in the Swedish population, in particular in never-smokers, and find out its association with demographics, comorbidities and symptoms. Methods Participants were recruited to t

With an aging population, an increased burden is put on national and regional healthcare and social systems. In Sweden, municipalities are required to provide inhabitants with the social services needed to enable them to live an independent life in their own home for as long as possible. Urban green spaces (UGS) may increase physical activity and social interaction, as well as improve wellbeing an

INTRODUCTION: The gerontological literature suggests that external housing-related control beliefs (HCB) influence activities of daily living (ADL) among older people, but knowledge is scarce for people with Parkinson's disease (PD). This longitudinal study aimed to explore the directions of the relationship between external HCB and ADL among people with PD.METHODS: Baseline (T1) and 3-year follow

ObjectiveThe 30-second Chair Stand Test (30s CST), a valid and reliable test evaluating lower extremity physical function, has been integrated into a digital eHealth program. We aimed to evaluate the agreement (inter-rater reliability) between digital self-assessment and in-person physiotherapist assessment as well as intra-rater test-retest reliability of digital self-assessment among persons wit

Objective: Meat intake is suggested to affect gut microbiome composition and the risk of chronic diseases. We aimed to identify meat-associated gut microbiome features and their association with host factors. Design: Gut microbiota species were profiled by deep shotgun metagenomics sequencing in 9669 individuals. Intake of white meat, unprocessed red meat, and processed red meat was assessed using

Sweden’s road traffic is responsible for a great part of the emissions of greenhouse gases in the country. Conventional vehicles, driven by fossil fuels, have low efficiency and emits environmentally destructive particles. Electric vehicles can be the solution! Electric vehicles have no local emissions while driving and the electric motors of today have an efficiency of above 90 %. But there are s

Popular Abstract in English Technological devices in our society are used on a daily basis. The speed in processing jobs and the memory capacity are two key parameters used to set their prices. The information is encoded with a binary system physically implemented on semiconductor circuits, where the bit 1 corresponds to a finite voltage and the bit 0 to zero voltage. In order to increase the speThis thesis aims to contribute to the field of time controlled charge and energy transport in mesoscopic systems. In Chapter 1, Chapter 2 and Chapter 3 a short review of the scattering matrix theory is presented, including both charge and energy transport, useful to understand the mathematical landscape used in Papers I, II, III and IV. Chapter 3 briefly presents the thermoelectric properties of m

The concept using inside information has its origin in Directive 2003/6/EC on insider dealing and market manipulation, Market Abuse Directive. The Market Abuse Directive requires Member States to prohibit and penalize market abuse. The expression using inside information is found in the prohibition on insider dealing in Article 2.1 in the Directive. This article requires Member States to prohibit Begreppet utnyttjande av insiderinformation har sitt ursprung i direktiv 2003/6/EG om marknadsmissbruk, MmD. MmD ålägger medlemsstaterna att förbjuda och beivra marknadsmissbruk. Uttrycket utnyttjande av insiderinformation återfinns i förbudet mot insiderhandel, som i huvudsak regleras i artikel 2.1 i MmD. Artikel 2.1 föreskriver att medlemsstaterna ska förbjuda en person som förfogar över insider

Summary Within the EU, cooperation in criminal matters has been established and the cooperation could be described as increasingly intensified. Since the Tampere Conclusions of 1999 the cooperation is on its way in the light of the EU’s aim to offer its citizens an area of freedom, security and justice. The cooperation in criminal matters has developed mainly throughout two strategies: mutual reco

Photoacoustic imaging can potentially map oxygen saturation (sO2) non-invasively. However, in-vivo human application is challenging due to spectral coloring, which causes a wavelength-dependent fluence attenuation and uncertainty in the estimation of chromophore concentrations deep in tissue. This study compares the performances of two previously proposed methods for spectral coloring compensation

CONTEXT: Type 2 diabetes is a growing global concern with serious complications, including kidney damage and cardiovascular morbidity and mortality. Monitoring albuminuria, which is associated with these complications, is crucial in optimal diabetes management. Gut microbiota composition has been suggested to impact albuminuria, but large studies with granular data are lacking.METHODS: We investig

Background: Higher meat intake has been associated with adverse health outcomes, including cardiovascular disease (CVD). This study investigated plasma metabolites associated with meat intake and their relation with cardiometabolic biomarkers, subclinical CVD markers, and incident CVD. Methods: Associations between self-reported meat intake and 1272 plasma metabolites were investigated in the SCAP

Policies that facilitate sustainability transformations require knowledge about the dynamics of complex socio-ecological systems, including biophysical mechanisms and diverse human-nature relationships. Such a comprehensive evidence base can only be built by integrating multiple types of knowledges. Ontology, epistemology, and semantics are a well-established terminology to structure and facilitat

Uppsatsen syftar till att ge en bild av hur små ägarledda företag ser på sin revisor och revisionen som utförs. Problemformuleringen har besvarats genom nio personliga intervjuer. Vi har kommit fram till att små företag har en dålig bild av vad revisorns arbete innebär. De är medvetna om att de måste revideras och tycker att det är en trygghet att bli reviderade, men de vet inte vem revisionen och

The thesis investigates lung function and the effects of rescue surfactant treatment in mechanically ventilated preterm human infants with respiratory distress syndrome (RDS), and the effects of ventilation at birth on the response to surfactant supplementation in preterm lambs. To assess lung function, the author recorded static pressure-volume (P-V) curves during passive deflation from total lun