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The derivation of first- and second-order backpropagation methods for fully-connected and convolutional neural networks

We introduce rigorous theory for deriving first and second order backpropagation methods for Deep Neural Networks (DNN) whilst satisfying existing theory in DNN optimization. We begin by formally defining a neural network with its respective components and state the first and second order chain rule with respect to its partial derivatives. The partial derivatives in the chain rule formula are rela

The IgG-degrading enzyme of Streptococcus pyogenes causes rapid clearance of anti-glomerular basement membrane antibodies in patients with refractory anti-glomerular basement membrane disease

In anti-glomerular basement membrane (anti-GBM) disease, IgG class autoantibodies induce rapidly progressive glomerulonephritis. Regrettably, many patients are diagnosed at a late stage when even intensive conventional treatment fails to restore renal function The endopeptidase IdeS (Immunoglobulin G degrading enzyme of Streptococcus pyogenes) (imliflidase) rapidly cleaves all human IgG subclasses

Homozygosity for the IgG2 subclass allotype G2M(n) protects against severe infection in hereditary C2 deficiency

Homozygous C2 deficiency (C2D) is the most common deficiency of the classical complement pathway in Western countries. It is mostly found in patients with autoimmune disease or susceptibility to bacterial infections and in healthy persons. We wished to assess to what extent other immunological factors might explain differences of susceptibility to infections in C2D. For this reason, 44 Swedish pat

Arsine, Stibine and Phosphine Derivatives of [Fe2(CO)6(μ-bdt)] (bdt = Benzenedithiolate) : Syntheses, Structures and Spectroscopic and Electrocatalytic Studies

The reactivity of the benzenedithiolate (bdt)-bridged complex [Fe2(CO)6(µ-bdt)] with arsine, stibine and phosphine ligands has been studied. The new mono- and disubstituted complexes [Fe2(CO)5(EPh3)(µ-bdt)] (E = As, 1; E = Sb 3) and [Fe2(CO)4(EPh3)2(µ-bdt)] (E = As, 2; E = Sb, 4) and the previously reported [Fe2(CO)4(PPh2H)2(µ-bdt)] (5) have been prepared by Me3NO-initiated carbonyl substitution r

Adsorption, desorption, and redox reactions at iron oxide nanoparticle surfaces

Soils play a critical role in the carbon (C) cycle by regulating the atmospheric carbon dioxide (CO2) levels, and correspondingly the Earth’s climate. However, there are still countless questions of how biological and geochemical soil processes affect the C cycle. To be able to predict future implications on the Earth’s climate, we need to understand these processes. Globally, soils store more C tIron oxide nanoparticles are involved in several important biogeochemical processes. The interfaces between aqueous solutions and iron oxide nanoparticle surfaces are found everywhere in nature, and the chemical and microbial processes occurring at these complex interfaces control e.g. nutrient and contaminant availability and transport. Recently, it has been shown that certain ectomycorrhizal (EC

Retoriska strider : Konkurrerande sanningar i dövvärlden

Popular Abstract in Swedish Under de senaste par decennierna har en specifik tolkning av döva och dövhet blivit alltmer etablerad på det ”officiella” dövområdet i Sverige, tillika anammat av såväl professionella som föräldrar till döva barn. Döva ska enligt detta synsätt hellre betraktas som tillhörande en kulturell och språklig minoritet än som handikappade. Medicinska strävanden att “laga defektIn the last couple of decades a particular interpretation of deaf and deafness has been established in ‘official’ arenas in Sweden. Deaf individuals, according to this view, should not be seen as disabled, but rather as belonging to a cultural and linguistic minority. Such views find expression in a locally established usage that may be termed a deaf culture discourse. Discourse can be seen as a

Framtidsveckan 2019 program final 190923

Framtidsveckan VETENSKAPSVECKA | 14–20 OKTOBER 2019 | LUNDS UNIVERSITET Omställningar Omställningar. Ordet väcker tankar om genom- gripande förändringar. I Svenska Akademiens Ordbok, vars redaktion vi har glädjen att ha just här i Lund, kan vi spåra en rad historiska använd- ningar av och associationer till ordet. Man kan omställa pjäserna på ett schackbräde, vilket för tankarna till strategier oc

https://www.lu.se/sites/www.lu.se/files/framtidsveckan_2019_program_final_190923.pdf - 2026-04-23

Proteomics and Phosphoproteomics Analysis of Parental and Cisplatin-Resistant Ovarian Cancer Cell Lines Treated with C26A6 and Volasertib

Mot smartare cellgiftsbehandling: Att förebygga behandlingsresistens vid äggstockscancer Äggstockscancer är den dödligaste gynekologiska cancertypen och kräver alltför många liv eftersom tumörer ofta blir resistenta mot behandling – särskilt mot cisplatin, vårt främsta försvar. För att rädda fler liv måste vi förstå hur denna resistens utvecklas och hur vi kan överlista den. I mitt examensarbete Ovarian cancer is the deadliest gynaecologic malignancy, with most patients diagnosed at an advanced stage and facing poor long-term survival. Resistance to cisplatin-based chemotherapy is a major clinical obstacle, yet its proteomic drivers remain poorly defined. In this study, I applied data-independent acquisition mass spectrometry with DIA-NN data processing to analyse one parental and two cis

TIDPLAN-20251113

Blad1 Senast datum Kl Datum t o m System Period Check Checklista inst/fak Information central hantering Länk 11/11/25 Raindance 10 ⃝ Registrera/komplettera intrastatuppgifter. Åtgärda alla poster som har status Ej komplett. Guide 11/25/25 Raindance 11 Bokföringsdag för Statsbudgetanslag – kommer med i saldolistor tidigare 11/25/25 Raindance 11 Bokföringsdag för Primulatransaktioner, kommer med i s

https://www.ekonomiwebben.lu.se/sites/ekonomiwebben.lu.se/files/2025-11/TIDPLAN-20251113.xlsx - 2026-04-23

Hållbart lärarskap: universitetsundervisning i förändring

Hållbart lärarskap: universitetsundervisning i förändring Hållbart lärarskap: universitetsundervisning i förändring Proceedings från Humanistiska och teologiska fakulteternas pedagogiska inspirationskonferens 2020 RED. SARA SANTESSON OCH KATARINA MÅRTENSSON | LUNDS UNIVERSITET ISBN 978-91-7267-453-0 När de humanistiska och teologiska fakulteternas pedagogiska inspirationskonferens gick av stapeln

https://www.ht.lu.se/fileadmin/user_upload/ht/dokument/Utbildning/Ha__llbart_la__rarskap.pdf - 2026-04-20

Inhibition of IL-4Rα reduces CCL26 in bronchial epithelial cells from COPD patients

Background Anti-interleukin (IL)-4Rα monoclonal antibodies (mAb) improve lung function and decreasethe number of exacerbations in patients with COPD type (T) 2 inflammation. However, the involvement ofearly innate immune responses underlying these treatment effects is not well known. We sought tounderstand the effect and mechanisms of IL-4Rα mAb treatment on bronchial epithelial cells (BECs) fromCBackgroundAnti-IL-4Rα monoclonal antibodies (mAb) improve lung function and decrease the number of exacerbations in patients with COPD type (T) 2 inflammation. However, the involvement of early innate immune responses underlying these treatment effects is not well known. We sought to understand the effect and mechanisms of IL-4Rα mAb treatment on bronchial epithelial cells from COPD patients under

The Chinese “Debt Trap”: Exhibit A - A critical analysis of the China–Sri Lanka Hambantota port affair

China’s financial actions along the BRI network has sparked a lot of controversies, one of these being the alleged usage of Debt Trap Diplomacy (DTD) in order to gain access to resources through debt relief that they otherwise would not be able to reach through traditional means. DTD practices can be considered part of the International Political Economy’s ‘blind spots’ due to their complexity and