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The Role of RB1 and Secondary Genomic Changes in the Development of Spindle Cell and Pleomorphic Lipomas

Spindle cell lipomas (SCL) and pleomorphic lipomas (PL) are today considered a single tumor entity (SCLPL). Atypical SCLPL, in contrast, represents a recently recognized related but distinct entity. Here we explored the correlation between genomic features and morphological aspects of SCLPL and atypical SCLPL and the role of the RB1 gene in tumor development. Seventy-one samples from 68 patients w

Impact of mono- or multitherapy on ocular surface health and quality of life after 5 years of follow-up in the Glaucoma Intensive Treatment Study (GITS)

Aim: To evaluate the impact of initial mono- versus multitherapy on the ocular surface and related quality of life after 5 years follow-up in the Glaucoma Intensive Treatment Study (GITS). Method: The study included patients with primary open-angle glaucoma and pseudoexfoliation glaucoma who completed 5-year follow-up in GITS. Assessment of ocular surface disease (OSD) symptoms was done using a Sw

Vernacularizing the Best Interests of the Child : Comparative Insights From Three Legal Systems

The study investigates how the Best Interests of the Child principle in the UN Children's Rights Convention (Article 3) has been adapted in custody disputes in Egypt, Sweden, and Uzbekistan. Although the Convention on the Rights of the Child offers a common normative benchmark, divergent legal cultures shape its domestic meaning: Egypt is governed by religious and state legal norms intersecting wi

A Proteomic Study of the Dual Oncogenic and Tumor-Suppressive Roles of SIRT3 in Lung and Breast Cancer Cell Lines

Mitochondria play a crucial role in metabolism and energy production by generating adenosine triphosphate (ATP) through oxidative phosphorylation. They also help maintain intracellular calcium levels, facilitate communication between the nucleus and cytoplasm, detoxify reactive oxygen species (ROS), and regulate apoptosis. Reversible acetylation of mitochondrial proteins is a key post-translationa

Restidsvariation för busstrafik - Analys av restidsvariationens omfattning

Restidsvariation för busstrafiken skapar osäkerhet för både passagerare och operatörer. För resenärer minskar möjligheten att förutse restid och ankomsttid vilket försvårar beslut kopplad till val av avgångstid eller möjligheten till effektiva byten. Operatörerna drabbas av minskad tidtabellstillförlitlighet och ökade kostnader på grund av större marginaler i tidtabellen. Tidigare forskning visar Travel time variability in bus traffic creates uncertainty for both passengers and operators. For passengers, unpredictable travel times complicate trip planning and transfers, while operators face reduced timetable reliability and increased costs from larger schedule buffers. Previous research shows that passengers value reductions in travel time variation more highly than reductions in average t

Stroke Action Plan for Europe 2018-2030 (SAP-E): mid-term review and update

OBJECTIVES: Implementation of the Stroke Action Plan for Europe (2018-2030) (SAP-E) was initiated in 2019. It is now updated at mid-term to reflect and respond to challenges for stroke care in Europe in 2025. METHODS: The SAP-E covers the entire chain of stroke care. The sections (state of the art, current status and targets) were developed by working groups and finalised based on inputs from the

Acceptable accuracy for medical AI : a survey of physicians and the general population in Sweden

OBJECTIVES: To identify the lowest sensitivity and specificity that physicians and the general population consider acceptable for medical artificial intelligence (AI), relative to current human performance.METHODS: In a nationwide, cross-sectional survey in Sweden, 2025, random samples of 500 physicians and 500 adults from the general population were mailed a questionnaire presenting three vignett

HbA(1c) Measured in Stored Erythrocytes Is Positively Linearly Associated with Mortality in Individuals with Diabetes Mellitus

Introduction: Observational studies have shown that glycated haemoglobin (HbA(1c)) is related to mortality, but the shape of the association is less clear. Furthermore, disease duration and medication may modify this association. This observational study explored the association between HbA(1c) measured in stored erythrocytes and mortality. Secondly, it was assessed whether disease duration and me

Daylight Utilization with Light Pipe in Farm Animal Production: A Simulation Approach

Light pipes offer a passive way to bring daylight inside deep buildings, such as agricultural buildings. However, the lack of reliable performance predictability methods for light pipes represents a major obstacle preventing their widespread use. This paper evaluates a simulation approach for performance prediction and identifies key light pipe design parameters affecting their daylight transmissi

Exposure to tetrachloroethylene in dry cleaning shops in the Nordic countries

Objectives: Tetrachloroethylene is the dominant solvent used in dry cleaning worldwide and many workers are potentially exposed. We report here on results of 1296 measurements of tetrachloroethylene undertaken in Nordic dry cleaning shops 1947–2001. Methods: We searched documents and files in the Nordic institutes of occupational health for air measurements of tetrachloroethylene. Repeated measur

Categorisation of Complications and Validation of the Clavien Score for Percutaneous Nephrolithotomy

Background: Although widely used, the validity and reliability of the Clavien classification of postoperative complications have not been tested in urologic procedures, such as percutaneous nephrolithotomy (PCNL). Objective: To validate the Clavien score and categorise complications of PCNL. Design, setting, and participants: Data for 528 patients with complications after PCNL were used to create

Radiographers' areas of professional competence related to good nursing care

Background: Radiographers' ability and competence is a matter of vital importance for patients. Nursing care is an integral part of the radiographer's work. The demand for high competence in clinical activities has increased in diagnostic radiology and has had an impact on the development of the profession. Aim: The aim was to describe the radiographer's areas of professional competence in relatio

Strategy for PLIF single-shot HCO imaging in turbulent methane/air flames

Formyl (HCO) has since long been recognized as a common intermediate species and a potential local indicator of the major heat release in hydrocarbon combustion. Consequently, the detection of HCO is desirable especially in turbulent flames of practical relevance. However, due to the low concentration and low fluorescence quantum yield, single-shot based detection of HCO with planar laser-induced

Late cardiovascular events after allogeneic hematopoietic stem cell transplantation: a retrospective multicenter study of the Late Effects Working Party of the European Group for Blood and Marrow Transplantation

Background Long-term outcome after hematopoietic stem cell transplantation including late transplant-related events is of increasing interest. The aim of this study was to evaluate the incidence of cardiovascular events after allogeneic HSCT and to search for their risk factors. Design and Methods This is a retrospective mutlicenter European Group of Blood and Marrow Transplantation (EBMT) analysi

Insertion of the CXXC domain of KMT2A into YAP1 : An unusual mechanism behind the formation of a chimeric oncogenic protein

Most neoplasia-associated gene fusions are formed through the fusion of the 5′-part of one gene with the 3′-part of another. We here describe a unique mechanism, by which a part of the KMT2A gene through an insertion replaces part of the YAP1 gene. The resulting YAP1::KMT2A::YAP1 (YKY) fusion was verified by RT-PCR in three cases of sarcoma morphologically resembling sclerosing epithelioid fibrosa

Physicians’ experiences and actions in making complex level-of-care decisions during acute situations within older patients’ homes : a critical incident study

Background: Complex level-of-care decisions involve uncertainty in which decisions are beneficial for older patients. Knowledge of physicians’ decision-making during acute situations in older patients’ homes is limited. Therefore, this study aimed to describe physicians’ experiences and actions in making complex level-of-care decisions during the assessment of older patients in acute situations wi

Assessing the Potential of a New Building Material in Bhutan in relation to Energy-efficiency and Social Aspects

This study explores the potential of new building insulation material specifically wood wool in Bhutanese Buildings. To cover social and performance-related aspects a quantitative and semi-structured qualitative interview study about the perception of current construction quality and methods and new building materials was conducted as well as a simulation study with different renovation scenarios.

Announcement AI Fellow

Announcement AI Fellow Raoul Wallenberg Institute of Human Rights and Humanitarian Law Stora Gråbrödersgatan 17 B | P.O. Box 1155 SE-221 05, Lund, Sweden | Phone +46 46 222 12 00 | Fax +46 46 222 12 22 RWI Research Exchange Cooperation for Academics in Belarus 1-30 November 2017 The Raoul Wallenberg Institute of Human Rights and Humanitarian Law (RWI) is an independent academic institution establi

https://rwi.lu.se/app/uploads/2017/09/Announcement-Research-Exchange-2017.pdf - 2026-04-21

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Together, we create an inclusive work environment for TRANSPEOPLE & NONBINARY at SCANIA and TRATON Inclusive behaviours Experiences Practicalities G lossary Support Sweden edition EVERYONE SHOULD FEEL SAFE TO BE THEMSELVES INCLUSION MEANS ALL OF US At Scania, we have trans and nonbinary colleagues who are out, visible, and leading by example. We also have others who aren’t sure if it’s safe to sha

https://www.saco.se/globalassets/lokala-akademikerforeningar/privat/scania/dokument/booklet---together-for-an-inclusive-work-environment-for-transpeople--nonbinary-at-scania--traton---sweden-edition-3.pdf - 2026-04-21

2016 1 Vaegledning vid relining av avloppsroer i fastigheter

Vägledning vid relining av avloppsrör i fastigheter A N D E R S H Ö I J E O C H T O R D A F K L I N T B E R G Rapport nr 2016:1 V ä g l e d n i n g v i d r e l i n i n g a v a v l o p p s r ö r 2 Förord Bland fastighetsägare och bostadsrättsföreningar ökar intresset för relining som komplement eller ersättning för stambyte. Det som lockar är främst ett lägre pris och mindre besvär för de boende un

https://www.renoveringscentrum.lth.se/sites/renoveringscentrum.lth.se/files/2025-09/2016_1_Vaegledning_vid_relining_av_avloppsroer_i_fastigheter.pdf - 2026-04-21