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Development and validation of a novel Simoa assay for NPTX2 in Alzheimer's disease and Down syndrome

INTRODUCTION: Synaptic dysfunction and loss are pathological hallmarks of neurodegenerative diseases. Neuronal pentraxin 2 (NPTX2), a presynaptic protein involved in synaptic plasticity, has been linked to cognitive decline in Alzheimer's disease (AD) and other neurodegenerative disorders. METHODS: We developed and validated a novel single molecule array (Simoa) for NPTX2 in cerebrospinal fluid, w

The 6G Computing Continuum (6GCC): Meeting the 6G computing challenges

6G systems, such as Large Intelligent Surfaces, will require distributed, complex, and coordinated decisions throughout a very heterogeneous and cell free infrastructure. This will require a fundamentally redesigned software infrastructure accompanied by massively distributed and heterogeneous computing resources, vastly different from current wireless networks.To address these challenges, in this6G systems, such as Large Intelligent Surfaces, will require distributed, complex, and coordinated decisions throughout a very heterogeneous and cell free infrastructure. This will require a fundamentally redesigned software infrastructure accompanied by massively distributed and heterogeneous computing resources, vastly different from current wireless networks.To address these challenges, in this

Efficacy of T-cell assays for the diagnosis of primary defects in cytotoxic lymphocyte exocytosis

Primary hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disorder associated with autosomal recessive variants in genes required for perforin-mediated lymphocyte cytotoxicity. A rapid diagnosis is crucial for successful treatment. Although defective cytotoxic T lymphocyte (CTL) function causes pathogenesis, quantification of natural killer (NK)–cell exocytosis triggered by K562 targe

Nurses’ refusals of patient involvement in their own palliative care

Background: Ideas of patient involvement are related to notions of self-determination and autonomy, which are not always in alignment with complex interactions and communication in clinical practice.Aim: To illuminate and discuss patient involvement in routine clinical care situations in nursing practice from an ethical perspective.Method: A case study based on an anthropological field study amongBackground:Ideas of patient involvement are related to notions of self-determination and autonomy, which are not always in alignment with complex interactions and communication in clinical practice.Aim:To illuminate and discuss patient involvement in routine clinical care situations in nursing practice from an ethical perspective.Method:A case study based on an anthropological field study among pa

Fabrication of Functional Molecularly Imprinted Materials using Nanoparticle Building Blocks

Popular Abstract in Undetermined Nanoparticles have attracted great interest in biomedicine and material science due to their unique and unconventional properties. Polymer nanoparticles containing pre-designed molecular recognition sites can be synthesized using molecular imprinting technique. Molecularly imprinted polymers (MIPs) have high affinity and selectivity that are similar to antibodies,Molecularly imprinted polymers (MIPs) have attracted great interest in many applications including bioseparation, chemical sensing, catalysis, drug delivery, etc. Recently, molecularly imprinted nanoparticles have become accessible due to a number of synthetic methods that have been developed. The high molecular binding selectivity, fast binding kinetics and colloidal stability make MIP nanopartic

Group G streptococcal IgG binding molecules FOG and protein G have different impacts on opsonization by C1q

Recent epidemiological data on diseases caused by beta-hemolytic streptococci belonging to Lancefield group C and G ( GCS, GGS) underline that they are an emerging threat to human health. Among various virulence factors expressed by GCS and GGS isolates from human infections, M and M-like proteins are considered important because of their anti-phagocytic activity. In addition, protein G has been i

The Higher Research Seminar: Ricardo Fabrino Mendonça, Federal University of Minas Girais - “Algorithms and Democracy”

13 maj 2026 13:15 till 14:30 | Seminarium Chair: Markus Holdo OUP’s book abstract:Algorithmic Institutionalism uniquely conceives of algorithms as institutions in contemporary societies, focusing on different dimensions of how algorithms structure decision-making and enact power relations. This work addresses the need for new analytical lenses to make sense of algorithms’ rising ubiquity in decisi

https://www.svet.lu.se/internt/evenemang/higher-research-seminar-ricardo-fabrino-mendonca-federal-university-minas-girais-algorithms-and - 2026-05-07

The Higher Research Seminar: Ricardo Fabrino Mendonça, Federal University of Minas Girais - “Algorithms and Democracy”

13 maj 2026 13:15 till 14:30 | Seminarium Chair: Markus Holdo OUP’s book abstract:Algorithmic Institutionalism uniquely conceives of algorithms as institutions in contemporary societies, focusing on different dimensions of how algorithms structure decision-making and enact power relations. This work addresses the need for new analytical lenses to make sense of algorithms’ rising ubiquity in decisi

https://www.svet.lu.se/evenemang/higher-research-seminar-ricardo-fabrino-mendonca-federal-university-minas-girais-algorithms-and - 2026-05-07

ALF Informationsmöte Projekt Niklas Nielsen 2024 240416 FINAL

PowerPoint-presentation Information om ALF NIKLAS NIELSEN, VICEDEKAN UTLYSNINGEN 2024 ALF • ALF står för Avtal om Läkarutbildning och Forskning • ALF-avtalet reglerar statens ersättning till regionerna för läkarutbildningens och den kliniska forskningens intrång i sjukvården. Avtalet förhandlas fram av staten och de sju regionerna som har läkarutbildning • Det första avtalet slöts 1989 • Nytt nati

https://www.intramed.lu.se/sites/intramed.lu.se/files/2024-04/ALF%20Informationsmo%CC%88te%20Projekt_Niklas%20Nielsen%202024_240416_FINAL.pdf - 2026-05-07

Förslag till masterexamensarbeten

Här annonserar vi kontinuerligt nya förslag till examensarbeten på avancerad nivå (GEOR02, 45 hp). De senaste förslagen ligger överst och gamla tas bort efter hand som de blir inaktuella. Kontakta huvudhandledaren om du är intresserad. Du är dessutom alltid välkommen att utifrån dina egna intressen diskutera olika möjligheter med dina lärare. Här kan du se exempel på tidigare masterarbeten. Notera

https://www.geologi.lu.se/utbildning/grund-avancerad-utbildning/masterutbildning-i-geologi/forslag-till-masterexamensarbeten - 2026-05-07

Genetiska algoritmer och deras tillämpningar inom konstruktion och design

This Master’s Thesis has shown possible applications of genetic optimization algorithms (GA) within design. A framework for structural optimization with genetic algorithms was built and used to show the possibilities of using GA to create concept designs given just the boundary conditions and requirements of a structure. A comparison between the optimization of the load bearing beam of an automate

Warming-induced contrasts in snow depth drive the future trajectory of soil carbon loss across the Arctic-Boreal region

The Arctic-Boreal region is projected to experience spatially divergent trends in snow depth following climate change. However, the impact of these spatial trends has remained largely unexplored, despite potentially large consequences for the carbon cycle. To address this knowledge gap, we forced a customised arctic version of the dynamic vegetation model LPJ-GUESS with daily CMIP6 outputs from a

Säkerhetsrådets argumentation kring Syrien och Libyen - En studie genom två IR perspektiv

Territorial and temporal are the civil wars in Libya and Syria relatively similar, despite the similarities, the events have given different results regarding resolutions in the Security Council. My questions are: How can you find the IR theories, realism and liberalism, in the arguments surrounding Libya and Syria in the UN Security Council? Can we find arguments that are both realistic and liber