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Adherence to isoniazid preventive therapy in children exposed to tuberculosis: a prospective study from Guinea-Bissau

OBJECTIVE: To assess adherence to isoniazid preventive therapy (IPT) in children exposed to adult pulmonary tuberculosis (TB) at home. METHODS: Children were enrolled on IPT if they were aged <= 5 years or 5-15 years and presented a tuberculin skin test induration of >= 1.0 mm. Children were included from the demographic surveillance system of the Bandim Health Project in Bissau, Guinea-Bissau. Th

Human Papillomavirus Antibody Reference Reagents for Use in Postvaccination Surveillance Serology

Suitably controlled serosurveillance surveys are essential for evaluating human papillomavirus (HPV) immunization programs. A panel of plasma samples from 18-year-old females was assembled, the majority of the samples being from recipients of the bivalent HPV vaccine. Antibody specificities were evaluated by three independent laboratories, and 3 pools that displayed no antibodies to any HPV type t

High levels of immunoglobulin E and a continuous increase in immunoglobulin G and immunoglobulin M by age in children with newly diagnosed type 1 diabetes

The incidence of type 1 diabetes (T1D) is increasing, either because of environmental factors accelerating onset of the disease or because of inducement of autoimmune diabetes in children who previously were at lower risk. High levels of immunoglobulin (Ig), specifically, IgM and IgA, and a low level of IgG were reported in adult patients; however no studies have analyzed the increasing incidence

Carbon availability triggers the decomposition of plant litter and assimilation of nitrogen by an ectomycorrhizal fungus

The majority of nitrogen in forest soils is found in organic matter-protein complexes. Ectomycorrhizal fungi (EMF) are thought to have a key role in decomposing and mobilizing nitrogen from such complexes. However, little is known about the mechanisms governing these processes, how they are regulated by the carbon in the host plant and the availability of more easily available forms of nitrogen so

Exploring History: a Mobile Inclusive Virtual Tourist Guide

In the present paper we report on the design decisions and the field test results of an inclusive mobile tourist guide app, the Time Machine. The historical information is conveyed by sound and the navigation information by haptics, while the app can be controlled eyes-free by a combination of on-screen and free-form gestures. To emphasize the eyes-free use, 9 of 11 test users recruited had severe

Random Number Generation by Chaotic Double Scroll Oscillator on Chip

Generation of good non-repeatable and non-predictable random number sequences is of increasing importance, both in security applications and in simulations. A novel, compact system is presented in which a secure random number is generated by sampling a chaotic system and using this bitstream as the input to a pseudo-random generator. An optional hash function can be used on the seed in order to de

The Kinetics Effect In SOFCs On Heat And Mass Transfer Limitations: Interparticle, Interphase And Intraparticle Transport

The transport processes in the porous, micro-structured electrodes are one of the least understood areas of research of the solid oxide fuel cell (SOFC). To enhance the knowledge of the transport process' impact on the performance in the electrodes, the micro-structure needs to be modeled in detail. But at these smaller scales, it can be both cost and time saving to first conclude at which scales,

Life cycle cost for different ventilation systems in single family houses

The purpose of an indoor climate system is to fulfil the required thermal comfort and provide satisfactory indoor air quality by using as little resources as possible. This study investigated the resulting energy use and life cycle cost from different ventilation systems for typical single family houses in the Nordic outdoor climate. Three ventilation systems were compared, namely exhaust ventilat

Modeling of various transport processes in a natural gas reformer

In this study, a three-dimensional calculation method has been developed to simulate and analyze steam reforming of natural gas, and the effects on various transport processes in a duct from a compact steam reformer. The reformer conditions such as the combined thermal boundary conditions on solid walls, mass balances associated with the reforming reactions and gas permeation to/from the porous ca

Microbial growth in stored dust samples as a function of the relative humidity

House dusts, collected for detection of microorganisms in buildings, sometimes have to be stored before measurement. It is possible that continued growth of microorganisms in the stored samples will increase the levels of CFU, chemical marker, biomass etc. The aim of this investigation was to assess the influence of relative humidity on microbial growth in dust samples. We have exposed dust sample

A novel method for direct measurement of complement convertases activity in human serum.

Complement convertases are enzymatic complexes that play a central role in sustaining and amplification of the complement cascade. Impairment of complement function directly or indirectly leads to pathologic conditions including higher infection rate, kidney diseases, autoimmune- or neurodegenerative diseases and ischemia-reperfusion injury. An assay for direct measurement of activity of the conve

Heat and mass balances of an intercooler in PEM Fuel Cell systems

In this paper, heat and mass balances of the intercooler in a 100 kW Proton Exchange Membrane Fuel Cell (PEMFC) system are analyzed by employing a commercial software IPSEpro. The compressor, ambient temperature, the humidification method and the PEMFCs cathode operating temperature were considered as the parameters influencing the heat and mass balances in the intercooler. Parametric studies of t

Characterization of a multi-swirler fuel injector using simultaneous laser based planar measurements of reaction zone, flow field and fuel distribution

Modern gas turbine spray combustors feature multiple swirlers with distributed fuel injection system for rapid fuel/air mixing and flame stabilization ensuring low NOx operations. In the present paper, we investigate the effects of different swirler designs on flame characteristics, stabilization, and behavior at lean blow out using a Triple Annular Research Swirler (TARS) burner. Simultaneous pla

C4b-binding protein in Alzheimer's disease: Binding to Abeta(1-42) and to dead cells.

In the Alzheimer's disease (AD) brain, binding of Clq within the Cl complex, the initiating molecule of the classical complement pathway, to apoptotic cells, DNA and amyloid-beta (Abeta), the major constituent of senile plaques, can initiate complement activation. However, the extent of activation is determined by the balance between activation and inhibition. Fluid-phase complement inhibitor C4b-

Assistive technology, human rights and poverty in developing countries. Perspectives based on a study in Bangladesh

Popular Abstract in Swedish Avhandlingen ger teoretiskt, juridiskt och empiriskt stöd för att genom hjälpmedelsförsörjning öka möjligheterna för människor med funktionshinder i låginkomstländer att förverkliga sina mänskliga rättigheter och minska sin fattigdom. Människor med funktionshinder är överrepresenterade bland världens fattiga. I utvecklingsländer lever mer än hälften av dem i extrem fatDeprived of human rights, more than half of all people with disabilities in developing countries live in extreme poverty. Although considered a prerequisite for equalization of opportunities, about nine out of ten of those who need assistive technologies do not have access to them. Little is known about the socioeconomic benefits of using assistive technology in low-income countries that can infor

Evolution of UV-B regulation and protection in plants

Plants have evolved under the influence of UV-B radiation and have acquired systems for monitoring it and investing appropriate resources for protection against it, i.e., filters, quenchers of radicals and reactive oxygen species, and repair systems. An hypothesis for how plants monitor radiation has been presented.

Image-based localization using hybrid feature correspondences

Where am I and what am I seeing? This is a classical vision problem and this paper presents a solution based on efficient use of a combination of 2D and 3D features. Given a model of a scene, the objective is to find the relative camera location of a new input image. Unlike traditional hypothesize-and-test methods that try to estimate the unknown camera position based on 3D model features only, or