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Specific targeting of antigen-presenting cells for immunotherapy

Immunotherapy, which involves strategies to activate, enhance or redirect immune responses to achieve long-lasting immunity, has the potential to play an important role in the treatment of a variety of diseases. This thesis, based on four original papers, highlights different approaches to modulate immune responses by specific targeting of antigen-presenting cells. The first two studies focuses o

Some Notes on Present European and Scandinavian Co-production Practices Through the Prism of ‘The Girl with the Dragon Tattoo’ (2009)

In a critique of the sometimes confusing ways in which the term transnational has been repeatedly used, Mette Hjort, in 2010 attempted to outline what she called a “typology of transnationalisms” in connection with contemporary audio-visual production (2009: 12–33). Hjort’s palpable purpose here is to more specifically illuminate and contextualize the increasingly more used concept of transnationa

A randomized comparison between league tables and funnel plots as an aid to health care decision-making

Objective Comparison of provider performance is commonly used to inform health care decision-making. Little attention has been paid to how data presentations influence decisions. This study analyzes differences in suggested actions by decision-makers informed by league tables or funnel plots.Design Decision-makers were invited to a survey and randomized to compare hospital performance using either

Heat transfer and friction factor in a dimple-pin fin wedge duct with various dimple depth and converging angle

Purpose - The dimple is adopted into a pin fin wedge duct which is widely used in modern gas turbine vane cooling structure trailing edge region. The purpose of this paper is to study the effects of dimple depth and duct converging angle on the endwall heat transfer and friction factor in this pin fin wedge duct. Design/methodology/approach - The study is carried out by using the numerical simulat

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Public debt soared in the late-medieval Low Countries: towns borrowed considerable sums from creditors and often ended up defaulting on their financial obligations. The author uses a tax inquiry from 1514 to demonstrate that villages also managed to create funded debt, which they secured on the public body of the village. As a result, around 1500 the majority of the villages in Holland owed annuit