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A major challenge of genome-wide association studies (GWASs) is to translate phenotypic associations into biological insights. Here, we integrate a large GWAS on blood lipids involving 1.6 million individuals from five ancestries with a wide array of functional genomic datasets to discover regulatory mechanisms underlying lipid associations. We first prioritize lipid-associated genes with expressi
BACKGROUND: Type 2 diabetes is one of the leading causes of chronic kidney failure, which increases globally and represents a significant threat to public health. People from the Middle East represent one of the largest immigrant groups in Europe today. Despite poor glucose regulation and high risk for early-onset insulin-deficient type 2 diabetes, they have better kidney function and lower rates
Aims: Transthyretin amyloid cardiomyopathy (ATTR-CM) is the cardiac manifestation of transthyretin amyloidosis (ATTR). The aim of this study was to estimate healthcare resource use for ATTR-CM patients compared with heart failure (HF) patients, in Denmark, Finland, Norway, and Sweden. Methods and results: Data from nationwide healthcare registers in the four countries were used. ATTR-CM patients w
I USA under 1960-talet växte intresset för kopplingen mellan juridiska reformer och ekonomisk och social utveckling i tredje världen. Detta var startskottet för en rörelse som kom att kallas Law and Development. Det var en löst sammansatt rörelse som bestod av såväl praktiska utvecklingsprojekt som teoretiska akademiska satsningar. Det övergripande målet var att hjälpa tredje världen ur fattigdom There was a growing interest in the United States during the 1960s regarding the relationship between legal reforms and economic and social development in the Third World. This was the start of a movement that became known as Law and Development. It consisted of both practical projects and theoretical studies. The overall goal was to help the Third World out of poverty and underdevelopment. There
This study examines the production of morphosyntax in Swedish-speaking children diagnosed with Developmental Language Disorder (DLD). Data from a Sentence Repetition Task was used to investigate if there is an implicational order according to Processability Theory (PT) in grammatical structures produced by school-age children with DLD. PT is a cognitive theory of language development that assumes
BACKGROUND: This study aimed to evaluate the prevalence of pathogenic/likely pathogenic cardiomyopathy variant carriers in a multiancestry US population and examine the risk of adverse clinical outcomes. METHODS: This retrospective cohort study included multiancestry US adults aged ≥18 years with sequencing data from the All of Us Research Program. Pathogenic/likely pathogenic variants in cardiomy
[Background/Context] AI assistants like GitHub Copilot are transforming software engineering; several studies have highlighted productivity improvements. However, their impact on code quality, particularly in terms of maintainability, requires further investigation. [Objective/Aim] This study aims to examine the influence of AI assistants on software maintainability, specifically assessing how the
Dilated cardiomyopathy (DCM) is a leading cause of heart failure and cardiac transplantation. We report a genome-wide association study and multi-trait analysis of DCM (14,256 cases) and three left ventricular traits (36,203 UK Biobank participants). We identified 80 genomic risk loci and prioritized 62 putative effector genes, including several with rare variant DCM associations (MAP3K7, NEDD4L a
Världens befolkning växer för var dag som går och därmed ökar även behovet av mat. Eftersom arealen odlingsbar mark är begränsad måste vi bli smartare i användandet av åkermark för att kunna föda fler människor. På grund av global uppvärmning och det faktum att växtbaserade livsmedel genererar mindre utsläpp än kött, borde fler resurser fokusera på att utveckla växtbaserade produkter. I dagsläget Due to the world’s growing population and an increase in food demand, new innovative food products need to be developed to maximize the use of limited farmland. Because of global warming and the fact that plant based products generate less greenhouse gases than meat based products, research should focus on new plant-based protein sources. Rapeseed press cake is a residue from rapeseed oil producti
Nyhetsmedierna i vårt samhälle är i förändring, och traditionell nyhetsbevakning blir allt svårare att skilja från populärkultur och nöjesmedier. Samtidigt uppvisar framför allt unga människor ett bristande intresse för traditionell medierapportering kring politiska frågor, och vänder sig istället till alternativa källor för information. En sådan källa är The Daily Show, ett satirprogram som fokus
Introduction: It is well known that urinary tract infection (UTI) during pregnancy is associated with preterm birth, but information about the risk of preterm birth depending on gestational week of infection is sparingly described in the literature. Material and Methods: An observational study based on data from Swedish registers including women giving birth 2014–2020 (n = 684 595). Pregnant women
Due to the threat climate change poses, the aviation industry needs to adapt. In the process to convert the aviation fleet into a more environmentally friendly fleet, using biofuels such as Sustainable Aviation Fuels as a drop-in fuel remains a promising option. To include biofuels, safety aspects need to be investigated, where combustion instabilities are important. Thermo-acoustic instabilities
BackgroundSuicide is a leading cause of premature mortality worldwide, but the impact of system-level mental health resources remains unclear despite the central role of psychiatric inpatient care and declining bed capacity. Prior research has yielded inconsistent findings with limited control for confounding. We aimed to estimate the effect of psychiatric inpatient bed availability on suicide mor
Bacteria encode diverse defence systems, including restriction-modification and CRISPR-Cas, that cleave nucleic acid to protect against phage infection. Bioinformatic analyses demonstrate that many recently identified antiphage defence operons comprise a nuclease and NTPase protein, suggesting that additional nucleic acid-targeting systems remain to be understood. Here we develop large-scale compa
Radio-based localization in dynamic environments, such as urban and vehicular settings, requires systems that efficiently adapt to varying signal conditions and environmental changes. Factors like multipath interference and obstructions introduce different levels of complexity that affect the accuracy of the localization. Although generalized models offer broad applicability, they often struggle t
Long RSH enzymes, Rel and RelA, are master regulators of bacterial (p)ppGpp alarmones levels. Bifunctional Rel transitions between a compact hydrolysis-competent (HD ON) state, a relaxed catalytically inactive (HD OFF/SYNTH OFF) state, and an elongated synthesis-competent (SYNTH ON) state, whereas RelA samples only the latter two. The distribution of these states is controlled by starved ribosomes
Möt Ketrin Jochecová, numera reporter för POLITICO:s Brussels Playbook.Meet Ketrin Jochecová, now a Reporter for POLITICO’s Brussels Playbook.
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https://www.byggmek.lth.se/utbildning/examensarbete/civilingenjoer/avslutade-arbeten/ - 2026-05-21
Institutionen för kulturvetenskaper, avdelningen för modevetenskap Institutionen för kulturvetenskaper, Besöksadress LUX, hus C, Helgonagatan 3, Lund Webbadress www.kultur.lu.se LITTERATURLISTA Sida 1 av 1 2 Sida 3 av 3 Kurslitteratur för Modevetenskap: Grundläggande filosofiska och vetenskapliga perspektiv (MODA25), 7,5 hp, VT 2026 Fastställd av institutionsstyrelsen eller motsvarande, 2012-10-0
https://www.ht.lu.se/media/utbildning/dokument/kurser/MODA25/20261/MODA25_VT26.docx - 2026-05-11
