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A numerical simulation is performed to identify the material parameters of an elastic/visco-plastic material under tensile impact loading. The identification is based on an inverse analysis using the Kalman filter technique and the finite element method. The input data to the inverse analysis are the time histories of the strains on specimens. The measurement errors can be treated reasonably by thA numerical simulation is performed to identify the material parameters of an elastic/visco-plastic material under tensile impact loading. The identification is based on an inverse analysis using the Kaiman filter technique and the finite element method. The input data to the inverse analysis are the time histories of the strains on specimens. The measurement errors can be treated reasonably by th

Background: Many inborn errors of metabolism (IEMs) may present as sudden infant death (SID). Nowadays, increasing numbers of patients with IEMs are identified pre-symptomatically by population neonatal bloodspot screening (NBS) programmes. However, some patients escape early detection because their symptoms and signs start before NBS test results become available, they even die even before the sa

In a rapidly digitalizing world, both tourism actors and researchers are striving to keep pace with developments in tourist information search. This is not an easy task, as research results are pointing at different directions. Moreover, while tourism research is indicating the importance of analogue and digital information sources in parallel, tourism actors focus mainly on digital development. T

Purpose: Choline is an essential nutrient for fetal and infant growth and development. Parenteral nutrition used in neonatal care lack free choline but contain small amounts of lipid-bound choline in the form of phosphatidylcholine (PC). Here, we examined the longitudinal development of serum free choline and metabolically related compounds betaine and methionine in extremely preterm infants and h

Previous studies have identified an association between osteoporotic fracture and a polymorphism affecting a Sp1 binding site in the first intron of the collagen type I alpha 1 gene (COL1A1). It is currently unclear, however, whether this association is direct or the result of linkage disequilibrium with other polymorphisms situated nearby. In this study we analyzed the relationship between four w

Indoor temperatures in apartment blocks are often indirectly controlled by the outdoor temperature using a feedforward control loop, in which the radiator supply temperature is a function of the outdoor tem- perature. However, this control principle cannot take into account heat gains or losses caused by tenants, electrical appliances, the sun, air leakage, etc., which may result in uneven indoor Indoor temperatures in apartment blocks are often indirectly controlled by the outdoor temperature using a feedforward control loop, in which the radiator supply temperature is a function of the outdoor temperature. However, this control principle cannot take into account heat gains or losses caused by tenants, electrical appliances, the sun, air leakage, etc., which may result in uneven indoor te

OBJECTIVE: Recent studies suggest that administration of O2 in patients with acute myocardial infarction may have negative effects. With the use of cardiac MRI (CMR), we evaluated the effects of supplemental O2 in patients with ST elevation myocardial infarction (STEMI) accepted for acute percutaneous coronary intervention (PCI).MATERIALS AND METHODS: This study was a randomized-controlled trial c

AIM: We studied the frequency of Achilles tendon xanthoma (ATX) in patients with acute coronary syndrome (ACS). Furthermore, we investigated the differences in clinical findings between ACS patients with and without ATX.METHODS: Patients with ACS (n=335) were admitted to the coronary care unit of Nippon Medical School between July 2011 and December 2014. Informed consent for the measurement of Ach

Objectives: To use a population pharmacokinetic approach to define maximally effective meropenem dosing recommendations for treatment of Acinetobacter baumannii and Pseudomonas aeruginosa infections in a large cohort of patients with septic shock. Methods: Adult patients with septic shock and conserved renal function, treated with meropenem, were eligible for inclusion. Seven blood samples were co

BACKGROUND: The elapsed time taken to diagnose tumors of the central nervous system in children and adolescents varies widely. The aim of the present study was to investigate such diagnostic time intervals at a national level in Sweden as they correlate with clinical features.METHODS: Data prospectively accumulated over a 4-year period in the Swedish Childhood Cancer Registry from patients aged 0-

Erving Goffman’s book Frame Analysis (1974) differs from several of his other texts (e.g. the praised books The Presentation of Self in Everyday Life, Encounters, Stigma and Asylums) in that it is probably read because of Goffman’s reputation rather than because it is considered to have an indispensable message. Frame Analysis doesn’t seem to be a book that you must read. It lacks the heuristic ch

Objectives: Rituximab (RTX) is an anti-CD20 antibody that selectively depletes B cells and has emerged as a therapy for ANCA-associated vasculitis (AAV) during the past decade. This study sought to quantify and determine potential risk factors for severe infections in AAV patients treated with RTX at rheumatology clinics in Mexico City, Mexico and Lund, Sweden. Methods: The study consisted of a re

Recent years have seen a rise in extreme heat event (EHE)-related deaths in India. However, the impact of specific temperature thresholds on health risks remains understudied. Using Distributed Lag Non-Linear Models (DLNM), we explored the link between EHEs, defined by various temperature thresholds, and mortality risk in Ahmedabad, India, from 2002 to 2018, considering a 21-day lag. We observed a

Purpose: Bilateral adrenalectomy (BA) still plays an important role in the management of Cushing's disease (CD). Nelson’s syndrome (NS) is a severe complication of BA, but conflicting data on its prevalence and predicting factors have been reported. The aim of this study was to determine the prevalence of NS, and identify factors associated with its development. Data sources: Systematic literature

Background: In the laparoscopic Roux-en-Y gastric bypass procedure, the gastrojejunal stoma is constructed with either a circular (CSD) or a linear stapling device (LSD). The diameter of the stoma following stapling with the 21 mm CSD is expected to be approximately 12 mm (diameter of the anvil). Measuring the stoma diameter after linear stapling is a little more complex since the remaining openin

The strive to create sustainable societies is often addressed through the lens of social, economic-, or environmental sustainability. However, this division fails to acknowledge existential dimensions of sustainability, i.e., the fundamental concern to sustain a good and meaningful life. This paper expands the notion of Existential Sustainability in relation to socio-material dimensions and built

Objectives: In radiotherapy, delineation uncertainties are important as they contribute to systematic errors and can lead to geographical miss of the target. For margin computation, standard deviations (SDs) of all uncertainties must be included as SDs. The aim of this study was to quantify the interobserver delineation variation for stereotactic body radiotherapy (SBRT) of peripheral lung tumours

Background and purpose — At our institution, new-borns with Barlow or Ortolani positive hips have been treated for 12 weeks with the von Rosen abduction splint until 2012 when the treatment length was halved. We inves-tigate whether acetabular development at 12 months of age and complications differ between hips treated with the von Rosen splint for 6 compared with 12 weeks. Patients and methods —