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Imatinib increases oxygen delivery in extracellular matrix-rich but not in matrix-poor experimental carcinoma

Background: Imatinib causes increased turnover of stromal collagen, reduces collagen fibril diameter, enhances extracellular fluid turnover and lowers interstitial fluid pressure (IFP) in the human colonic carcinoma KAT-4/HT-29 (KAT-4) xenograft model. Methods: We compared the effects of imatinib on oxygen levels, vascular morphology and IFP in three experimental tumor models differing in their co

Diagnostic Accuracy of Candidate Magnetic Resonance Imaging Knee Osteoarthritis Definitions Versus Radiograph in an Acute Anterior Cruciate Ligament Injury Cohort

Objective: We tested the diagnostic accuracy of previously proposed magnetic resonance imaging (MRI) osteoarthritis (OA) definitions in a cohort after acute anterior cruciate ligament (ACL) injury. Methods: We studied participants with posteroanterior and lateral knee radiographs and MRI 5 years after ACL injury, scored using the Anterior Cruciate Ligament Osteoarthritis Score. Radiographic OA (RO

Synthesis and transfection efficiencies of new lipophilic polyamines

A homologous series of lipophilic polyamines was synthesized and evaluated for DNA delivery and transfection efficiency. The series contained 1,4-butanediamine, 1,8-octanediamine, 2-[2-(2-amino-ethoxy)-ethoxy]-ethylamine, homospermidine, and homospermine covalently attached via their N-1 terminus to a 3,4-bis(oleyloxy)-benzyl motif. In addition, homospermidine and homospermine were also attached v

Streptococcal surface proteins activate the contact system and control its antibacterial activity.

Group G streptococci (GGS) are important bacterial pathogens in humans. Here we investigate the interactions between GGS and the contact system, a pro-coagulant and pro-inflammatory proteolytic cascade, which upon activation also generates antibacterial peptides. Two surface proteins of GGS, protein FOG and protein G (PG), were found to bind contact system proteins. Experiments utilizing contact p

Comparison of two hyaluronan drugs and placebo in patients with knee osteoarthritis. A controlled, randomized, double-blind, parallel-design multicentre study

Objective. To compare the efficacy and safety of intra-articular injections of two different hyaluronan preparations and placebo in patients with knee osteoarthritis. Methods. In a randomized, patient- and observer-blind, placebo-controlled and multicentre trial with parallel groups, 210 patients, aged 60 yr or above, with knee osteoarthritis were included in a per protocol analysis. The patients

Identification of Helicobacter pylori and other Helicobacter species by PCR, hybridization, and partial DNA sequencing in human liver samples from patients with primary sclerosing cholangitis or primary biliary cirrhosis

Helicobacter pylori was identified in human liver tissue by PCR, hybridization, and partial DNA sequencing. Liver biopsies were obtained from patients with primary sclerosing cholangitis (n = 12), primary biliary cirrhosis (n = 12), and noncholestatic liver cirrhosis (n = 13) and (as controls) normal livers (n = 10). PCR analyses were carried out using primers for the Helicobacter genus, Helicobac

Continuous glucose monitoring vs conventional therapy for glycemic control in adults with type 1 diabetes treated with multiple daily insulin injections the gold randomized clinical trial

IMPORTANCE The majority of individuals with type 1 diabetes do not meet recommended glycemic targets. OBJECTIVE To evaluate the effects of continuous glucose monitoring in adults with type 1 diabetes treated with multiple daily insulin injections. DESIGN, SETTING, AND PARTICIPANTS Open-label crossover randomized clinical trial conducted in 15 diabetes outpatient clinics in Sweden between February

Litteraturlista MULM53 VT25 Specialpedagogik

Litteratur Specialpedagogik VT24 Sida 1 av 4 Beslutad i utbildningsnämnden för Musiklärarutbildningen 2024-11-06 Litteraturlista – MULM53 Specialpedagogik Bernmalm, Emil. (2022). Gemenskapens gränser: Stigmahantering och pluralistisk fostran i gymnasieskolan. Institutionen för utbildningsvetenskap, Humanistiska och teologiska fakulteterna, Lunds universitet. [9 sidor, se pdf i Canvas] Bernmalm, Em

https://www.mhm.lu.se/sites/mhm.lu.se/files/2024-12/Litteraturlista%20MULM53%20VT25%20Specialpedagogik.pdf - 2026-04-27

Publication in stem cells international

Research Article Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus Natalia Avaliani,1 Ulrich Pfisterer,2 Andreas Heuer,2,3 Malin Parmar,2 Merab Kokaia,1 and My Andersson1 1Epilepsy Centre, Lund University Hospital, Lund, Sweden 2Developmental Neurobiology, Lund University, Lund, Sweden 3Molecular Neuromodulation, Lund University, Lund, S

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_stem_cells_international.pdf - 2026-04-27

Echoes of Distress: Maternal Malaise and the Pathways of Intergenerational Socioeconomic Outcomes

This study investigates how early exposure to maternal mental distress shapes offspring’s long‐ term socioeconomic pathways by leveraging the 1970 British Cohort Study. Maternal distress was measured when the cohort members were aged 5, 10, and 16 years via the 24-item Malaise Inventory. Structural Equation Modeling is employed to estimate (1) the direct effect of maternal malaise on offspring’s a

Informationssida med schema

Sid 1 MVEN03 - Miljövetenskap: Analys och metodik, 15 hp HT 2016 Länk: Preliminärt schema 160615 Kursansvarig: Nina Reistad NR nina.reistad@fysik.lth.se Lärare: Sofia Hydbom SH sofia.hydbom@biol.lu.se Estelle Larsson EL estelle.larsson@skane.se Per Erik Isberg PEI per-erik.isberg@stat.lu.se Pål Axel Olsson PAO pal_axel.olsson@biol.lu.se Martijn van Praagh MVP martijn.van_praagh@mv.lu.se Sofia Mebr

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/informationssida_med_schema.pdf - 2026-04-27

Program ESSUG Användardagar Maj 2025

Program ESSUG:s användardagar 2025 fysiskt på plats i Lund alternativt digitalt Tid: 20 maj 2025 kl 13-17, 21 maj 2025 kl 9-13 Plats: Allhelgona kyrkogata 14, Lunds universitet, Eden alternativt digitalt via Zoom (anmälan krävs). Anmälan, senast 29 april 2025: https://forms.office.com/e/ZVG2N0Wzi1 Begränsat antal platser, först till kvarn. Tisdagen den 20 maj 2025, Eden 132B (frivillig, endast på

https://www.ub.lu.se/sites/ub.lu.se/files/2025-07/Program%20ESSUG%20anv%C3%A4ndardagar%20maj%202025.pdf - 2026-04-27

Pandemins experter : en undersökning av representationen bland expertröster i lokalrapporteringen av covid-19

This study aims to analyze the gender representation of experts in the local newspaper Sydsvenskan during the covid pandemic. Furthermore, this study seeks to gain insights about the results of the processes that determine who is interviewed as an expert during a crisis situation such as the covid pandemic. A total of 369 articles were examined during the period from 1 May 2021 to 31 October 2021

Fraktionerna och deras förändring under det femte och sjätte århundradet e. Kr

The purpose of this thesis is to examine the changes that the Circusfactions underwent in the fifth and sixth centuries A.D and what underlying factors contributed to it. Basically, the intention with this thesis is to investigate how the circusfactions come to advance from mere cheering-associations, with a single interest, horseracing and the games, to a state employed claque with crucial civic

Inequality as a Cause of Systemic Banking Crises ̶ Some New Theory and Evidence

The thesis argues that systemic banking crises and inequality go hand in hand, with inequality in front. Through showing how factors commonly found to influence banking crises, such as household and business debt levels, asset prices, default ratios, and credit growth (all important in Minsky-type bubbles) theoretically can be attributed to decreasing relative wages of households, and/or concentra