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Randomized Trial of Sacroiliac Joint Arthrodesis Compared with Conservative Management for Chronic Low Back Pain Attributed to the Sacroiliac Joint

BACKGROUND: Sacroiliac joint pain is increasingly recognized as a cause of low back pain. We compared the safety and effectiveness of minimally invasive sacroiliac joint arthrodesis using triangular titanium implants and conservative management in patients with chronic sacroiliac joint pain. METHODS: This study was a prospective, multicenter randomized controlled trial of adults with chronic sacro

Variability in functional outcome and treatment practices by treatment center after out-of-hospital cardiac arrest : analysis of International Cardiac Arrest Registry

Purpose: Functional outcomes vary between centers after out-of-hospital cardiac arrest (OHCA) and are partially explained by pre-existing health status and arrest characteristics, while the effects of in-hospital treatments on functional outcome are less understood. We examined variation in functional outcomes by center after adjusting for patient- and arrest-specific characteristics and evaluated

From Substance Use Disorders in Life to Autopsy Findings : A Combined Case-Record and Medico-Legal Study

Objectives: Several studies have shown mortality and suicide risk in substance use disorders, and autopsy findings with respect to the used substances. However, there seems to be a gap in the knowledge about substances misused in life and at death at the within-person level. Methods: All consecutive, autopsied patients during 1993 to 1997, who had been in contact with the Addiction Centre in Malmö

Quantum interference in transport through almost symmetric double quantum dots

We theoretically investigate transport signatures of quantum interference in highly symmetric double quantum dots in a parallel geometry and demonstrate that extremely weak symmetry-breaking effects can have a dramatic influence on the current. Our calculations are based on a master equation in which quantum interference enters as nondiagonal elements of the density matrix of the double quantum do

Origin of the π -band replicas in the electronic structure of graphene grown on 4H -SiC(0001)

The calculated electronic band structure of graphene is relatively simple, with a Fermi surface consisting only of six Dirac cones in the first Brillouin zone - one at each K̄. In contrast, angle-resolved photoemission measurements of graphene grown on SiC(0001) often show six satellite Dirac cones surrounding each primary Dirac cone. Recent studies have reported two further Dirac cones along the

Immune challenge induces terminal investment at an early breeding stage in female zebra finches

The "terminal investment" hypothesis proposes that individuals with low future survival prospects will gain from increasing investment in the current reproductive event even though it will reduce the chances of future reproduction even further. Such investments have previously been found to occur mainly during the late stages of the breeding event, that is, encompassing a short period of elevated

The genetic diversity, morphology, biogeography, and taxonomic designations of Ammonia (Foraminifera) in the Northeast Atlantic

The genetic diversity, morphology and biogeography of Ammonia specimens was investigated across the Northeast (NE) Atlantic margins, to enhance the regional (palaeo)ecological studies based on this genus. Living specimens were collected from 22 sampling locations ranging from Shetland to Portugal to determine the distribution of Ammonia genetic types across the NE Atlantic shelf biomes. We success

Role of forest regrowth in global carbon sink dynamics

Although the existence of a large carbon sink in terrestrial ecosystems is well-established, the drivers of this sink remain uncertain. It has been suggested that perturbations to forest demography caused by past land-use change, management, and natural disturbances may be causing a large component of current carbon uptake. Here we use a global compilation of forest age observations, combined wit

Assessment of the Food-Swallowing Process Using Bolus Visualisation and Manometry Simultaneously in a Device that Models Human Swallowing

The characteristics of the flows of boluses with different consistencies, i.e. different rheological properties, through the pharynx have not been fully elucidated. The results obtained using a novel in vitro device, the Gothenburg Throat, which allows simultaneous bolus flow visualisation and manometry assessments in the pharynx geometry, are presented, to explain the dependence of bolus flow on

TCF4 (E2-2) harbors tumor suppressive functions in SHH medulloblastoma

The TCF4 gene encodes for the basic helix–loop–helix transcription factor 4 (TCF4), which plays an important role in the development of the central nervous system (CNS). Haploinsufficiency of TCF4 was found to cause Pitt-Hopkins syndrome (PTHS), a severe neurodevelopmental disorder. Recently, the screening of a large cohort of medulloblastoma (MB), a highly aggressive embryonal brain tumor, reveal

Freedom or Love? : Marriage, Single Life, and the Road to Happiness in Swedish 1920s Magazines

This article analyses discourses about self-supporting women in Swedish women’s magazines in the 1920s, after the attainment of legal equality in marriage and the acquisition of the right to vote. The self-supporting middle class woman was a controversial figure in this context. On the one hand symbolizing freedom and independence, she was on the other hand ridiculed and labelled mannish and unatt

Synaptic vesicle protein 2A as a potential biomarker in synaptopathies

Measuring synaptic density in vivo using positron emission tomography (PET) imaging-based biomarkers targeting the synaptic vesicle protein 2A (SV2A) has received much attention recently due to its potential research and clinical applications in synaptopathies, including neurodegenerative and psychiatric diseases. Fluid-based biomarkers in proteinopathies have previously been suggested to provide

Towards meaningful youth participation in science-policy processes : A case study of the Youth in Landscapes Initiative

In the context of complex intergenerational challenges such as climate change and sustainable development, it is increasingly important for scientists and policy-makers to actively engage with and support the meaningful participation of youth in policy and decision-making. This research evaluates the effectiveness and impact of the Youth in Landscapes Initiative in supporting the active participat

Impact of gender on echocardiographic characteristics in heart transplant recipients

Aims: Assessment following heart transplantation (HTx) is routinely performed using transthoracic echocardiography. Differences in long-term mortality following HTx related to donor-recipient matching have been reported, but effects of gender on cardiac size and function are not well studied. The aims of this study were to evaluate differences in echocardiographic characteristics of HTx recipients

A recommender geoportal for geospatial resource discovery and recommendation

Geoportals have been widely implemented by national spatial data infrastructures (NSDI) to provide users with the ability to search for geospatial resources over the Internet. This paper proposes an approach that can improve the functionalities of the conventional geoportals by adding recommendation capabilities to the execution mechanisms of geoportals. The geoportals with recommendation capabili