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Ceramics and change. An overview of pottery production

In southern African Iron Age studies, there are few attempts to systematically apply and include laboratory analyses when studying archaeological ceramic materials. As demonstrated in this paper, such analyses help to understand technological aspects such as raw materials, manufacturing techniques and vessel function. Combined with vessel shape and decoration as well as ethnographic studies the re

Life years lost-comparing potentially fatal late complications after radiotherapy for pediatric medulloblastoma on a common scale

BACKGROUND: The authors developed a framework for estimating and comparing the risks of various long-term complications on a common scale and applied it to 3 different techniques for craniospinal irradiation in patients with pediatric medulloblastoma. METHODS: Radiation dose-response parameters related to excess hazard ratios for secondary breast, lung, stomach, and thyroid cancer; heart failure,

Prevalence of stenoses and occlusions of brain-supplying arteries in young stroke patients.

OBJECTIVE: Atherosclerosis is believed to be a minor cause of TIA and stroke in younger and middle-aged patients. However, data from large cohorts are limited. This study investigates the prevalence of extracranial and intracranial atherosclerosis in stroke and TIA patients aged 18-55 years in the multinational sifap1 study. METHODS: From the sifap1 cohort (n = 5,023), we analyzed a subset of pati

Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro

Background & Aims: The robust association between non-alcoholic fatty liver disease (NAFLD) and the genetic variant I148M (rs738409) in PNPLA3 has been widely replicated. The aim of this study was to investigate the effect of the PNPLA3 I148M mutation on: (1) hepatic secretion of very low density lipoproteins (VLDL) in humans; and (2) secretion of apolipoprotein B (apoB) from McA-RH 7777 cells

Management of Tritium in European Spallation Source

The European Spallation Source (ESS) will produce tritium via spallation and activation processes during operational activities. Within the location of ESS facility in Lund, Sweden site it is mandatory to demonstrate that the management strategy of the produced tritium ensures the compliance with the country regulation criteria. The aim of this paper is to give an overview of the different aspects

Note on off-shell relations in nonlinear sigma model

In this note, we investigate relations between tree-level off-shell currents in nonlinear sigma model. Under Cayley parametrization, all odd-point currents vanish. We propose and prove a generalized U(1) identity for even-point currents. The off-shell U(1) identity given in [1] is a special case of the generalized identity studied in this note. The on-shell limit of this identity is equivalent wit

Arsenite adsorption on cryogels embedded with iron-aluminium double hydrous oxides: Possible polishing step for smelting wastewater?

Arsenic is among the most toxic elements and it commonly exists in water as arsenite (As(III)) and arsenate (As(V)) ions. As(III) removal often requires a pre-oxidation or pH adjustment step and it is a challenge to adsorb As(III) at circumneutral pH. In this study, iron-aluminium double hydrous oxides were synthesized and incorporated into cryogels. The resulting composite cryogels were evaluated

A Longitudinal Study of Changes in Asylum Seekers Ability Regarding Activities of Daily Living During Their Stay in the Asylum Center

The aim was to assess change in activities of daily living (ADL) ability amongst asylum seekers and if there were any difference between tortured and non-torture following a 10 months post-arrival period, and if self-reported health and exposure to torture were factors related to change in ADL-ability. The study was a combined baseline, follow-up correlational study amongst individuals from Afghan

Abnormal atrial activation is common in patients with arrhythmogenic right ventricular cardiomyopathy.

INTRODUCTION: Structural right atrial abnormalities have been described in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC). However, little is known about electrocardiographic signs of atrial involvement in ARVC because no systematic studies have been conducted. METHODS: P-wave-triggered signal-averaged orthogonal electrocardiogram from 40 ARVC patients (46 ± 15 years, 16 fema

Personality psychology as the integrative study of traits and worldviews

Personality psychology inevitably studies human beings not just as mechanical systems, but also as rational agents, whose experiences and actions are imbued with meaning. The purpose of this paper is to clarify the implications of taking this core element of personality psychology seriously, and to thereby contribute to the development of an integrative and normative framework for the field. I arg

Making sense of sensory perceptions across languages and cultures

This article has two aims: (i) to give an overview of research on sensory perceptions in different disciplines with different aims, and on the basis of that (ii) to encourage new research based on a balanced socio-sensory-cognitive approach. It emphasizes the need to study sensory meanings in human communication, both in Language with a capital L, focusing on universal phenomena, and across differ

Fc epsilon RI levels and frequencies of peripheral blood dendritic cell populations in allergic rhinitis

The dendritic cell (DC) lineage encompasses a diverse population of cells with unique subtype-specific functions. In peripheral blood, four DC subsets have been identified based on their distinct expression of CD1c, CD141, CD16, and CD123, and these subpopulations exhibit functional properties in immune responses. However, their respective roles in allergic diseases, such as rhinitis, are unclear.

A somatic mutation of GFI1B identified in leukemia alters cell fate via a SPI1 (PU.1) centered genetic regulatory network.

We identify a mutation (D262N) in the erythroid-affiliated transcriptional repressor GFI1B, in an acute myeloid leukemia (AML) patient with antecedent myelodysplastic syndrome (MDS). The GFI1B-D262N mutant functionally antagonizes the transcriptional activity of wild-type GFI1B. GFI1B-D262N promoted myelomonocytic versus erythroid output from primary human hematopoietic precursors and enhanced cel

Chronology and styles of glaciation in an inter-fjord setting, northwestern Svalbard

A 30-m-thick sedimentary succession at Leinstranda on the southwestern coast of Br circle divide ggerhalv circle divide ya, northwestern Svalbard, spans the two last glacial-interglacial cycles and reveals information on glacial dynamics, sea-level changes and the timing of these events. We investigated the deposits using standard stratigraphical and sedimentological techniques, together with grou

Integrated Modeling of a Laboratory Setup for a Large Deformable Mirror

We study a concept for a low-cost, large deformable mirror for an Extremely Large Telescope. The use of inexpensive voice-coil actuators leads to a poorly damped faceplate, with many modes within the desired control bandwidth. A control architecture, including rate and position feedback to add damping and stiffness, for the faceplate has been presented in our previous papers. An innovative local c

Acute lung injury and ARDS in acute pancreatitis: Mechanisms and potential intervention

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) in acute pancreatitis still represents a substantial problem, with a mortality rate in the range of 30%-40%. The present review evaluates underlying pathophysiological mechanisms in both ALI and ARDS and potential clinical implications. Several mediators and pathophysiological pathways are involved during the different phases o

Evaluating 5 and 8 pH-point titrations for measuring VFA in full-scale primary sludge hydrolysate

An evaluation of 5 and 8 pH-point titrimetric methods for determining volatile fatty acids (VFAs) was conducted, and the results were compared for tap water and primary treated wastewater at the laboratory scale. These techniques were then applied to full-scale primary sludge hydrolysate, and the results were compared with those obtained via gas chromatography. The comparison showed that the VFA c