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Background The impact of the prophylactic vaccine against human papillomavirus (HPV) types 6, 11, 16, and 18 (HPV6/11/16/18) on all HPV-associated genital disease was investigated in a population that approximates sexually naive women in that they were "negative to 14 HPV types" and in a mixed population of HPV-exposed and -unexposed women (intention-to-treat group). Methods This analysis studied

OBJECTIVES:: Brain tumour has few established determinants. We assessed to which extent risk of brain tumour was related to metabolic syndrome factors in adults. METHODS:: In the Me-Can project, 580 000 individuals from Sweden, Austria, and Norway were followed for a median of 10 years after baseline measurement. Data on brain tumours were obtained from national cancer registries. The factors of m

Windstorms have caused severe damage on several occasions in Sweden during the last century. A general concern about future projections of climate extremes has raised questions on the variations and impacts of windstorms. The main objective with this work was to reach a deeper understanding of the variability and possible trends in ­windstorms, and related storm impacts in forests. This was achiev

Abstract is not available

Ever since IT started to become important and strategic assets in organizational practices, systems acquisitions have been a challenging and complex endeavor. There are seemingly never ending reports of unsuccessful IT acquisitions and lack of systems acquisition competence (beställarkompetens in Swedish). The aim of this thesis is to shed deeper light on what systems acquisition competence is abo

Artikeln utgör en presentation av forskningsprojektet Regeringsformen och förvaltningen – styrning och rättslig reglering, för vilket Vetenskapsrådet har beviljat medel. Projektet syftar till att undersöka styrningen av den svenska förvaltningen ur ett rättsligt perspektiv. Huvudfokus är styrningen och den rättsliga regleringen idag, men för att förstå den, studeras den ur ett utvecklingsperspekti

Omdöme ”Teckenspråkiga döva” är en rik avhandling. Den innehåller spännande och djuplodande empiriskt material. Fredäng täcker samtidigt in ett stort fält från individnivå med familj och skola till lokalföreningar och riksorganisation och till hur samhället ställer sig i olika frågor. Det är sannolikt att de sociala typer som Päivi Fredäng tar upp, om hur döva ser på sig själva och sin dövhet l

Chronic mitral regurgitation is often accompanied by left atrial and ventricular remodeling and elevated natriuretic peptide levels. Our aim was to examine the relation between severe preoperative left atrial enlargement and changes in hemodynamics and natriuretic peptide levels after mitral valve surgery.

Training studies in children have suggested that endurance training can give enlargement of cardiac dimensions. This relationship has not been studied on a population-based level in young children with objective methods. A cross-sectional study was made of 248 children (140 boys and 108 girls), aged 8-11 years, from a population-based cohort. Left ventricular end-diastolic diameter (LVDD) and left

Dopamine replacement for Parkinson's disease (PD) have seen three major iterations of improvements since the introduction of l-3,4-dihydroxyphenylalanine (l-DOPA) pharmacotherapy: dopamine receptor agonists, ex vivo gene transfer for cell transplantation and most recently in vivo gene therapy. In this chapter, we describe the principles behind viral vector-mediated enzyme replacement in PD. We foc