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Sámi Resurgence through Heritage Work : Exploring Sámi Cosmology in Negotiation with Lutheran Christianity
With the aim to reach deeper insights into dynamics of resilience and resurgence in Sámi systems of knowledge, this article explores how Sámi worldviews and knowledges are enacted and passed on despite violent efforts of erasure by colonial state actors and settler colonialists. I analyze a variety of sources—interviews, a podcast, a documentary and a magazine—to highlight Sámi resilience and resu
Conferencing in times of climate crisis and Covid-19 : feminist and queer reflections on the digital shift in academic work
This article employs a holistic understanding of environmental, social, and economic sustainability to explore the interaction between neoliberalism, climate crisis, digitalization, and academic work with a focus on its everyday aspects. Drawing our experience of organizing an online conference during the Covid-19 pandemic and our dialogue with conference participants, we first problematize the pr
How to build nice robots : Ethics from theory to machine implementation
This thesis investigates morality from a computational perspective by examining how machines can be developed with capacities for moral reasoning and action. It addresses how to overcome interdisciplinary boundaries between moral philosophy and computer science (Paper I), proposes a virtue-theoretic framework for artificial moral cognition (Papers II and III), and highlights issues of using normat
Women resisting border regimes : Two case studies from Eastern and Northern Europe
This chapter explores border regimes in Northern and Eastern Europe and analyses the transnational regime at the core of practices of intimacy, labour, economy and reproduction for the construction of the state and the nation. The authors argue that the women they followed during fieldwork refused to conform to norms around sexual desire, authentic subjectivity and ‘rational’ legitimised economic
Vad påverkar studenters närvaro? En intervjustudie med studenter
In literature (e.g. Meulenbroek & van den Bogaard, 2013; Romer, 1993) a correlation between high class attendance and higher study results are historically shown for first-cycle engineering education. However, a tendency towards significantly lower student attendance at learning activities has been experienced by the teaching staff during the latest ten years and particularly among introductorIn literature (e.g. Meulenbroek & van den Bogaard, 2013; Romer, 1993) a correlation between high class attendance and higher study results are historically shown for first-cycle engineering education. However, a tendency towards significantly lower student attendance at learning activities has been experienced by the teaching staff during the latest ten years and particularly among introductor
Advanced Digital Technologies in Migration Management : Data Protection and Fundamental Rights Concerns
Associations of Prenatal Mercury Exposure and PUFA with Telomere Length and mtDNA Copy Number in 7-Year-Old Children in the Seychelles Child Development Nutrition Cohort 2
BACKGROUND: Telomere length (TL) and mitochondrial DNA copy number (mtDNAcn) variations are linked to age-related diseases and are associated with environmental exposure and nutritional status. Limited data, however, exist on the associations with mercury exposure, particularly early in life.OBJECTIVE: We examined the association between prenatal mercury (Hg) exposure and TL and mtDNAcn in 1,145 S
On the Trustworthiness of Trusted Third Parties
Trusted Third Parties (TTPs) are a standard building block in secure systems and are used in many cryptographic protocols. A TTP is an entity which facilitates interaction between the users in a system. As the name suggests, TTPs are trusted, and can thus be relied on to perform critical parts of a protocol without need for external scrutiny. Due to this property, they can serve the role of making
Flexibelt arbetsliv : Utmaningar för ledarskap, kultur och kommunikation
Det pågår just nu en omvandling av arbetslivet – arbete är inte bundet till en specifik plats eller tid i samma utsträckning som tidigare. Distansarbete och möjlighet till flexibla arbetstider har förekommit sedan decennier tillbaka, men den snabba digitaliseringen och den globala pandemin Covid-19 förändrade våra arbetsformer och kommunikationsmönster i raketfart. Efter pandemin har många organis
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A scoping review of studies in informal second language learning : Trends in research published between 2000 and 2020
In recent years, research interest in second language use and acquisition beyond the classroom has grown considerably. However, terminological confusion and definitional differences have made it difficult to compare findings and discover trends across studies, and more broadly synthesise new insights and developments. Therefore, this scoping review is intended to provide an overview of when, where
Impact of Spatiotemporal Rainfall Distribution and Underlying Surface Changes on Flood Processes in Meijiang River Basin, China
This study reports on the impact of rainfall patterns and land surface changes on flood dynamics in the Meijiang River Basin, located in the upper reaches of the Ganjiang River. We formulated a range of rainfall patterns and spatial distribution scenarios and employed the MIKE SHE model to evaluate variations in flood volume, flood peak, and the timing of flood peaks. We found that under comparabl
Real-World Performance of Integrative Clinical Genomics in Pediatric Precision Oncology
Despite significant improvement in the survival of pediatric patients with cancer, treatment outcomes for high-risk, relapsed, and refractory cancers remain unsatisfactory. Moreover, prolonged survival is frequently associated with long-term adverse effects due to intensive multimodal treatments. Accelerating the progress of pediatric oncology requires both therapeutic advances and strategies to m
Investigation of long non-coding RNAs in extracellular vesicles from low-volume blood serum specimens of colorectal cancer patients
Colorectal cancer (CRC) is the second most prevalent cancer type worldwide, which highlights the urgent need for non-invasive biomarkers for its early detection and improved prognosis. We aimed to investigate the patterns of long non-coding RNAs (lncRNAs) in small extracellular vesicles (sEVs) collected from low-volume blood serum specimens of CRC patients, focusing on their potential as diagnosti
Optimized procedure for high-throughput transcriptome profiling of small extracellular vesicles isolated from low volume serum samples
OBJECTIVES: Small extracellular vesicles (EVs) contain various signaling molecules, thus playing a crucial role in cell-to-cell communication and emerging as a promising source of biomarkers. However, the lack of standardized procedures impedes their translation to clinical practice. Thus, we compared different approaches for high-throughput analysis of small EVs transcriptome.METHODS: Small EVs w
Alternative Complement Pathway in Carotid Atherosclerosis : Low Plasma Properdin Levels Associate With Long-Term Cardiovascular Mortality
BACKGROUND: Complement activation may promote atherosclerosis. Yet, data on the to which extent complement, and more specifically the alternative complement pathway, is activated in patients with carotid atherosclerosis and related to adverse outcome in these patients, are scarce.METHODS AND RESULTS: We measured, by ELISA, plasma levels of factor D, properdin, C3bBbP (C3 convertase), and factor H
Imatinib as a key inhibitor of the platelet-derived growth factor receptor mediated expression of cell surface heparan sulfate proteoglycans and functional properties of breast cancer cells
Cell surface heparan sulfate proteoglycans (HSPGs), syndecans and glypicans, play crucial roles in the functional properties of cancer cells, such as proliferation, adhesion, migration and invasion. Platelet-derived growth factor (PDGF)/PDGF receptor (PDGF-R) mediated signaling, on the other hand, is highly associated with cancer progression. Specifically, PDGF-Rα and PDGF-Rβ expressions documente
