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Gastroesophageal reflux disease (GERD) is a prevalent condition observed across various medical specialties, including gastroenterology, otorhinolaryngology, surgery and primary care. Despite the routine prescription of proton pump inhibitors, some patients fail to experience adequate symptom relief. This review delves into the multifactorial mechanisms of reflux, which extend beyond hydrochloric

Herbicides are one of the most heavily applied groups of pesticides globally. Whilst research on herbicides in relation to bees is growing, we still have more to learn about how bees may interact with herbicides and the subsequent consequences for bee health. As herbicides are designed to kill the plants they are applied to, bees and other pollinators may interact with them in a different way to o

The bryophyte flora of the canyon Rövarekulan in Skåne, southern-most Sweden, has been thoroughly investigated as reported herein. Including historic records, a total of 200 taxa have been reported, whereof 181 were found in 2023–2024. The most spectacular finding was that of a small population of Didymodon luridus, until recently regarded as extinct in Sweden, growing in a crack in a south-facing

The story of a literature review

Using real-variable methods, we characterise multipliers for general classes of Hardy-Orlicz spaces, unifying and extending several classical results due to Hardy and Littlewood; Duren and Shields; Paley; and others. Applications of our results include inequalities involving Fourier coefficients and Fourier transforms of elements of Hardy-Orlicz spaces and their duals, as well as embeddings into s

The present study investigates the thermoacoustic instability for triangular bluff-body stabilized flames using high fidelity Large Eddy Simulations with finite-rate chemistry. The study includes premixed propane-air combustion, studying the triggering of the thermoacoustic instability for different parameters such as, incoming turbulence intensity, inlet velocity and temperature, and equivalence

The doctoral period is often described as a linear path, omitting the human dimensions of becoming a scholar. In this volume, the imaginary of the PhD education in Sweden is expanded through the metaphor of the PhD wanderer— an early-career academic venturing into unknown terrains, sometimes becoming lost, at other times finding exciting directions, committing to new routes, and encountering new t

The availability of high-quality datasets is crucial for developing behavior prediction algorithms in autonomous vehicles. This paper highlights the need to standardize the use of certain datasets for motion forecasting research to simplify comparative analysis and proposes a set of tools and practices to achieve this. Drawing on extensive experience and a comprehensive review of current literatur

Modern-day opportunities allow musicians to divert from normalised, widespread perceptions of their artistic needs and pursue diverse career paths. This thesis uses autoethnographic methods to explore a classical pianist's navigation between contrastingfields, such as international relations, higher education management, and music and performance.Artistic citizenship and discourse theory have been

The semi-natural grasslands of the Aso Caldera, Japan, have historically played a key role in maintaining biodiversity, tourism, and water resources. However, they are now in decline due to a decrease in the number of agricultural workers and an aging workforce, as well as structural changes and stagnation in the agricultural and livestock industries. This study focused on the water resource maint

A Palaeolithic diet is an efficacious dietary approach for glycaemic control in type 2 diabetes. Causal mechanisms are body weight loss and glucometabolic effects from differences in included food groups, macronutrient composition, fibre content, and glycaemic load. The aim was to test the hypothesis that characteristic food group differences between a Palaeolithic and a diabetes diet would cause

BACKGROUND: Brain-derived neurotrophic factor (BDNF) plays a critical role in neuronal development and neural connectivity, and has been implicated in the pathophysiology of Major Depressive Disorder (MDD). However, its predictive value for MDD onset remains unclear. This study examined whether baseline BDNF levels are associated with incident MDD in middle-aged women.MATERIAL AND METHODS: In this

Smart city control rooms are prominent components of the smart city discourse. They embody a long-­ standing dream to visualize and manage multiple urban processes in real time through the collation of data flows. Previous research has produced important insights into the design, construction and operation of these facilities. However, this research has largely overlooked the fundamental changes t

BackgroundThe purpose was to evaluate the prognostic impact of aryl hydrocarbon receptor (AHR) genotypes in relation to lifestyle and adjuvant treatments in breast cancer.MethodsAHR genotyping was performed on genomic DNA from 1701 patients included 2002–2016 in Lund, Sweden, and followed for up to 15 years. Eight AHR polymorphisms and eight haplotypes were analysed using survival and interaction

Disruptions in circadian rhythm, partly controlled by the hormone melatonin, increase the risk of type 2 diabetes (T2D). Accordingly, a variant of the gene encoding the melatonin receptor 1B (MTNR1B) is robustly associated with increased risk of T2D. This single-nucleotide polymorphism (SNP; rs10830963; G-allele) is an expression quantitative trait locus (eQTL) in human pancreatic islets, conferri

Background: Prolactin receptor (PRLR) signaling affects breastfeeding and potentially breast cancer treatment response. Methods: The prognostic impact of 20 PRLR single nucleotide polymorphisms (SNPs) in relation to adjuvant treatment groups in patients with primary breast cancer (n = 1701, 2002–2016, Sweden) was evaluated. Genomic DNA was genotyped on Illumina OncoArray, and survival analyses wit