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Antibiotics are considered to be among the most frequent causes of drug-related acute liver injury (ALI). Although many ALIs have mild and reversible clinical outcomes, there is substantial risk of severe reactions leading to acute liver failure, need for liver transplant, and death. Recent studies have raised concerns of hepatotoxic potential related to the use of fluoroquinolones.MethodsThis stu
The effect of human recombinant cystatin C, a cysteine proteinase inhibitor, on bone resorption in vitro was evaluated. Bone resorption was assessed by analyzing the release of 45Ca and 3H from mouse calvarial bones prelabeled in vivo by injections with 45Ca or [3H]proline, respectively. In 24 h cultures, cystatin C (50 micrograms/ml) significantly inhibited the release of 45Ca and 3H stimulated b
Literature compilation.Part of the project: “Histories of Philosophy in Global Perspective”. Under the heading "Histories of Philosophy", you will find a compliation of all works on the history of philosophy known to us, sorted by the language of publication. You will also find a list of all works on the global history of philosophy and a collection of works on the theory of the historiography of philosophy. All these d
Courtship displays are typically conspicuous, elaborate and composed of concomitant signals occurring in different sensory modalities. Although multimodal signals have received increasing attention over the past years, technical issues, in particular the lack of appropriate recording and analytical methods, have long restricted large-scale systematic study of their function. Here, we investigated
Parents face a trade-off when allocating limited resources to reproduction and self-maintenance, and this can result in differential investment in individual offspring when rearing multiple offspring simultaneously. In birds with biparental care, it is not well understood how each parent allocates its resources to different chicks of the same brood. Theory suggests that parental investment depends
Objective: Both auditory and visual hypersensitivity are clinical features of mental fatigue after acquired brain damage or in neurological disorders. Both types of hypersensitivity are also associated with attention deficits, especially in neurodevelopmental syndromes. The aim of this study was to examine auditory and visual hypersensitivity, and associations to attention, in a group of children
BACKGROUND: The advent of direct-to-consumer (DTC) genetic testing (GT) has sparked a number of debates regarding the scientific validity of tests, their broad health and ethical implications for society as well as their legal status. To date, relatively few empirical studies have been published regarding this phenomenon. We conducted a survey of European clinical geneticists to gauge their awaren
The available carbon (C) to phosphorus (P) ratio in soil is regulated by extracellular hydrolases for C and P acquisition by microbes and plants. However, the stoichiometric relationship between acquiring C and P in paddy rhizosphere and bulk soils remains unclear. The objective was to explore the underlying mechanisms of C and P acquisition stoichiometry in rhizosphere and bulk soils in response
This article explores medical assessments of the age of unaccompanied minors seeking asylum in Denmark, to show how, through the medical and bureaucratic aspects of the process, it serves as an imperialist technology of control, as those judged under 18 have greater protection in the asylum system. Since the biggest group of people who are age-estimated in Denmark are Afghans, the author looks at
Reduced ventricular longitudinal shortening measured by atrioventricular plane displacement (AVPD) and global longitudinal strain (GLS) are prognostic markers in heart disease. This study aims to determine if AVPD and GLS with cardiovascular magnetic resonance (CMR) are independent predictors of cardiovascular (CV) and all-cause death also in heart failure with reduced ejection fraction (HFrEF). P
Innovation är en kraft som står bakom förändringen i vår vardag. Till exempel att prata med någon på andra sidan jordklotet med en mobil eller beställa dina matvaror eller skor på din smarta mobil. Det var otänkbart för mindre än 40 år sedan. Vi vill naturligtvis att innovationer i vårt samhälle ska fortsätta förbättra våra liv. Men innovationsverksamhet och att generera nya produkter, tjänster, aInnovation measurement and metrics have fascinated scholars from several disciplines over the last decade. Allthese diverse contributions, however, have resulted in a current state of knowledge that is signified by largenumbers of articles without clear integration and synthesis. Therefore, this thesis aims to increase thetheoretical, empirical, and practical understanding of innovation measuremen
