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The metabolic syndrome and risk of myocardial infarction in familial hypertension (Hypertension Heredity in Malmö Evaluation study).

OBJECTIVES: The aim of this study was to examine whether three main definitions of the metabolic syndrome (MetS) - WHO, National Cholesterol Education Program-Adult Treatment Panel III and International Diabetes Federation - identify the same individuals and are able to predict incident myocardial infarction (MI) in families with essential hypertension. METHODS: The tested definitions were prospec

Betonstrategie für den Oresund-Tunnel

Abstract in German Zur Überwachung der Qualität des Betons für den Oresund-Tunnel wurde eine umfassende Betonspezifikation ausgearbeitet. Die geforderte Lebensdauer des Bauwerks ist mit 1 00 Jahre angesetzt - und dies bei aggressiven, betonangreifenden Umgebungsbedingungen: Meerwasser, Taumittel, Frost-Tau-Wechsel, Wasserdruck usw. Der vorliegende Beitrag gibt Überblick über die wichtigsten AnfordA comprehensive concrete specification has been prepared to control the quality of the concrete for the Øresund Link. The required service life of the structure is 100 years in environmental conditions that are aggressive to concrete ; marine environment deicing agents, freeze-thaw action, water pressure etc. This paper gives a short review of the most important requirements for the concrete to be

Immune responses against fibronectin modified by lipoprotein oxidation and their association with cardiovascular disease.

Abstract. Dunér P, To F, Alm R, Gonçalves I, Fredrikson GN, Hedblad B, Berglund G, Nilsson J, Bengtsson E (Malmö University Hospital, Lund University, Lund, Sweden). Immune responses against fibronectin modified by lipoprotein oxidation and their association with cardiovascular disease. J Intern Med 2009; doi: 10.1111/j.1365-2796.2008.02067.xObjectives. Accumulation and subsequent oxidation of LDL

Prospects of stem cell therapy for replacing dopamine neurons in Parkinson's disease.

In Parkinson's disease (PD), the main pathology is a loss of nigrostriatal dopamine (DA) neurons. Clinical trials with intrastriatal transplantation of human embryonic mesencephalic tissue have shown that grafted DA neurons reinnervate the striatum, restore striatal DA release and, in some patients, induce major clinical benefit. Stem cells could provide an unlimited source of DA neurons for trans

CTH17-2: Energy-efficient cooperative relaying over fading channels with simple relay selection

We consider a cooperative wireless network where the source broadcasts data to relays, some or all of which cooperatively beamform to forward the data to the destination. The network is subject to an overall outage constraint. We generalize the standard approaches for cooperative communications in two respects: (i) we explicitly model and factor in the cost of acquiring channel state information (

Enhanced expressions of microvascular smooth muscle receptors after focal cerebral ischemia occur via the MAPK MEK/ERK pathway.

BACKGROUND: MEK1/2 is a serine/threonine protein that phosphorylates extracellular signal-regulated kinase (ERK1/2). Cerebral ischemia results in enhanced expression of cerebrovascular contractile receptors in the middle cerebral artery (MCA) leading to the ischemic region. Here we explored the role of the MEK/ERK pathway in receptor expression following ischemic brain injury using the specific ME

Implied Volatility and Risk Aversion in a Simple Model with Uncertain Growth

We show that a simple equilibrium model with uncertain growth is able to simultaneously generate patterns in implied volatility and risk aversion that are similar to the ones observed in the data. In addition, the model produces an implied pricing kernel that is increasing for particular levels of wealth.

Activity of motor cortex neurons during backward locomotion.

Forward walking (FW) and backward walking (BW) are two important forms of locomotion in quadrupeds. Participation of the motor cortex in the control of FW has been intensively studied, while cortical activity during BW has never been investigated. The aim of this study was to analyze locomotion-related activity of the motor cortex during BW, and compare it to that during FW. For this purpose, we r

Mouse development is not obviously affected by the absence of dermatan sulfate epimerase 2 in spite of a modified brain dermatan sulfate composition.

Dermatan sulfate epimerase 2 (DS-epi2), together with its homologue DS-epi1, transform glucuronic acid into iduronic acid in dermatan sulfate polysaccharide chains. Iduronic acid gives dermatan sulfate increased chain flexibility and promotes protein binding. DS-epi2 is ubiquitously expressed and is the predominant epimerase in brain. Here we report the generation and initial characterization of D

Ratings of L-DOPA-induced dyskinesia in the unilateral 6-OHDA lesion model of Parkinson's disease in rats and mice.

This unit provides detailed protocols for establishing rodent models of L-DOPA-induced dyskinesia. The 6-hydroxydopamine (6-OHDA) lesion procedure is described in more detail for mice than for rats since the lesioning procedure in rats has been described extensively in previous work and is less difficult to perform. Unlike primate models, rodent models of L-DOPA-induced dyskinesia are relatively s