The positive correlation between elevated expression of wingless-type mammary tumor virus integration site family member 5A (WNT5A) and metastatic potential in melanoma has been extensively explored. However, detailed mechanistic aspects regarding how WNT5A promotes increased melanoma aggressiveness remains unknown. Myristoylated alanine-rich C-kinase substrate (MARCKS), an intracellular protein c

Den här komparativa studien redogör för skillnaderna mellan Sverige och England vid uppsägningsfall som hänför sig till personliga skäl, specifikt misskötsamhet och sjukdom. Syftet är att se hur de båda länderna skiljer sig åt innan och vid uppsägningsfall som hänför sig till personliga skäl. För att göra jämförelsen är studien grundad i en rättsdogmatisk metod. De rättskällor som främst använts äThis thesis discusses the differences in case of dismissal in forms of personal matters such as misconduct and illness in Sweden and England. The purpose is to see how the dismissal takes place before and during the dismissal in the two countries. In order to do this comparative study, the legal dogmatic method have been used. The sources of law that have been used is primarily precedents, the two

I Sveriges olycksstatistik är män tydligt överrepresenterade och detta syns främst i olyckor inom trafiken och förgiftningsolyckor. Bland trafikolyckor är ca 75 % av de som omkommer män och främst unga män i åldrarna 18 - 25. Detta samband mellan genus och olyckor kan vara av intresse för Sveriges trafiksäkerhetsarbete för att i längden uppnå Nollvisionen. Frågan är vad som skulle kunna göras och During decades men, and especially young adults, have been overrepresented in statistics for traffic accidents. It is known that this trend is linked to men’s riskier behaviour when driving. Sweden has a zero vision (Nollvisionen), which states that no one should die or be seriously injured in traffic and is applied for all road safety work. Therefore, it is of interest to work to prevent risk beh

How to increase trade flows in today's globalized world is a relevant topic and the incentives to do so are exemplified by the WTO Trade Facilitation Agreement that came into force in 2017. Inefficient trade procedures have proven to aggravate and decrease trade. Inefficient trade procedures could be obtaining, preparing and submitting documents about the traded good to authorities, as well as

The marine ecosystem in the Baltic Sea is affected by multiple stress factors, e.g. eutrophication and deoxygenation, overfishing and anthropogenic pollution. Here we evaluate the short-term trends of dissolved oxygen in bottom waters and changes in the primary productivity within a coastal inlet in the Baltic Sea. Undisturbed sediment cores (mean sedimentation rate 0.5 cm yr-1) were retrieved fro

Andelen förnybar kraft växer i produktionsmixen, med löften om att ersätta traditionell fossilintensiv kraftproduktion. I kombination med en trend mot elektrifiering av transporter uppstår nya möjligheter som användning av elfordon för att hantera variabiliteten i förnybar kraftproduktion. Detta examensarbete utforskar potentialen i att använda sådana balanserande tekniker, ofta refererade till soThe share of renewable power grows in the generation mix, wielding promises of substituting traditional CO2-intensive power production. In combination with the trend towards electrification of transport, opportunities are emerging to use electric vehicles for balancing the variability of the renewable power sources. This master thesis explores the potential for such balancing techniques, often ref

The size of the pension payments is a result of how well the pension capital has been invested by the life insurance company. The laws for how much of the pension capital the life insurance companies are able to invest, and how much they need to keep as capital requirement, are under investigation. This is regulated by the risk measure value at risk. Finansinspektionen has released a test report,

Transition metal complexes can activate otherwise unreactive C-H bonds to form C-C bonds, which is of great use for the synthetic chemist. One type of organometallic framework that has gained fame in the last decade is the pincer complex because of its stability, and how easily its steric and electronic properties can be altered. Palladium is one of the transition metals commonly used in pincer co

This master thesis collaborates with Axis Communications, which is a Swedish video camera company. The mission for the thesis was to take advantage of Axis developed or developing technology to explore the data value in the retail industry and design a data visualization interface. Shopping via online shopping platforms, customers will leave their shopping journey data and the data can be recorde

Vägar slits konstant och kräver konstant förbättringar och ombyggnationer. För att möjliggöra detta krävs personer som befinner sig ute på vägarna. Tekniken har gått framåt inom området trafiksäkerhet men skulle behöva förbättras ytterligare om vägarbetare ska vara säkra på sin arbetsplats. Även trafiken har förändrats över åren. Idag finns fler fordon på vägarna än aldrig förr. Bilarna är säkrareRoads are constantly worn down and demands improvements and reconstructions. To make this possible there has to be road workers on the road. Road safety has been improved along the years but can still be improved more. Today there are more vehicles on the road than ever before. The cars are more safe and therefore is encouraging to higher speeds as they are driven together with all safety features

The European commission have set targets regarding the reduction of emission of greenhouse gases, the improvement of the energy efficiency and the use of renewable resources of energy respectively by 20 % by the year of 2020. Swedish targets are even more ambitious compared to the European Commission that aims to reduce the greenhouse gas emissions by 40 %, improve the energy efficiency by 20 % an

This dissertation aims to investigate the Swedish private sector, with focus on the share of women in leading positions, and its effect on firms’ financial stability in terms of stock return volatility. This thesis is based on AllBright’s three lists from 2018 which rank Swedish listed firms after their level of gender equality within the companies’ top management. With respect to the six-sigma th

Den globala #metoo-rörelsen fick under hösten 2017 ett stort genomslag i Sverige. Ett massivt antal vittnesmål om upplevelser av sexuella trakasserier och övergrepp spred sig genom sociala medier under haschtagen #metoo. Ojämställdhet på arbetsplatser i form av sexuella trakasserier och övergrepp är i förlängningen ett samhälleligt problem. Uppsatsen söker undersöka vilken möjlighet #metoo-rörelse

All humans are unique, we have different characteristics and we make different decision. This is a challenge when it comes to modelling human behaviour. The models we design are based on mathematics where there is no room for inconsistencies such that are present in human behaviour. So how do we account for this when we try to model human behaviour in evacuation modelling? Most models provide the

Melanoma is one of the most serious types of skin cancer. The disease occurs due to abnormal growth in melanocytes, usually caused by DNA damage, occurring from ultraviolet radiation, weak immune system and/or family heritage. Melanoma only represents about 4% of all diagnosed skin cancers but accounts for more than 80% of all deaths related to skin cancer. The poor prognosis in melanoma is mainly

As an increasing number of species drift onto the IUCN’s list of endangered species, it has become increasingly important to understand the fundamental aspects that are essential in maintaining the fitness of these threatened species. Using tracking data from 75% of a sample of Swiss juvenile Red Kites during their wintering period in Spain, various bioclimatic predictors (BCMPs) were taken into

This thesis is an explorative qualitative study based on interpretative phenomenological analysis, utilizing the social-psychological theory of functional attitudes to explore the attitudes of Lebanese university students toward homosexuality and the motivational bases of such attitudes. Five core groups of such attitude motivations were identified. Perceptions of the way one’s society relates to

Under de senaste åren har man sett en kraftig ökning av bostadsbyggandet, vilket kan innebära en stor prisrisk på den svenska bostadsmarknaden. Vid studerande av tillskottet av bostäder och prisnivån i olika kommuner ser utvecklingen dock olika ut. Kommunerna följer inte samma mönster. I detta arbete studeras sambandet mellan nyproduktion av bostäder och prisutvecklingen, samt utreds hur nyproduktIn recent years, there has been an increase in new housing, which may imply a large price risk in the Swedish housing market. When investigating the new housing and price levels in different municipalities, the developments are different. The municipalities do not follow the same pattern. In this thesis, the relation between new housing and development in price is studied, as well as how new housi