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Direct Conversion of Human Stem Cell-Derived Glial Progenitor Cells into GABAergic Interneurons cells Article Direct Conversion of Human Stem Cell-Derived Glial Progenitor Cells into GABAergic Interneurons Jessica Giacomoni 1, Andreas Bruzelius 2 , Christina-Anastasia Stamouli 2 and Daniella Rylander Ottosson 2,* 1 Group of Developmental and Regenerative Neurobiology, Wallenberg Neuroscience Cente
Cell‐based therapy for Parkinson's disease: A journey through decades toward the light side of the Force Eur J Neurosci. 2018;1–9. | 1wileyonlinelibrary.com/journal/ejn 1 | INTRODUCTION It was with great sadness that we all received the news about Tom’s passing. He was a force for good in the Parkinson’s disease (PD) community and he will be greatly missed. For Tom, nothing was too serious that yo
doi:10.1016/j.expneurol.2006.04.022 Retrovirally delivered Islet-1 increases recruitment of Ng2 expressing cells from the postnatal SVZ into the striatum Nina Rogelius a,⁎, Josephine B. Jensen a,b, Cecilia Lundberg a, Malin Parmar a,b,⁎ a Wallenberg Neuroscience Center, Department of Experimental Medical Science, Lund University, BMC A11, SE-221 84 Lund, Sweden b Lund Strategic Center for Stem Cel
Dual modulation of neuron‐specific microRNAs and the REST complex promotes functional maturation of human adult induced neurons Dual modulation of neuron-specific microRNAs and the REST complex promotes functional maturation of human adult induced neurons Marcella Birtele1, Yogita Sharma1, Srisaiyini Kidnapillai2, Shong Lau1, Thomas B. Stoker1,3, Roger A. Barker1,3, Daniella Rylander Ottosson1,2,
https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_febs_lett.pdf - 2025-05-10
Journal of Parkinson’s Disease 8 (2018) S131–S137 DOI 10.3233/JPD-181488 IOS Press S131 Review Repairing the Brain: Cell Replacement Using Stem Cell-Based Technologies Claire Henchcliffea,∗ and Malin Parmarb,∗ aDepartment of Neurology, Weill Cornell Medical College, and Department of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York NY, USA bWallenberg Neuroscience Center and Lund Ste
PII: S0925-4773(00)00324-5 Gene expression pattern Expression of Meis and Pbx genes and their protein products in the developing telencephalon: implications for regional differentiation HaÊkan Toresson1, Malin Parmar, Kenneth Campbell* Wallenberg Neuroscience Center, Division of Neurobiology, Section for Developmental Neurobiology, Lund University, SoÈlvegatan 17, S-223 62 Lund, Sweden Received 24
doi:10.1016/j.mcn.2008.04.008 Reprogramming of neonatal SVZ progenitors by Islet-1 and Neurogenin-2 Nina Rogeliusa, Josephine B. Hebsgaarda,b, Cecilia Lundberga, Malin Parmara,b,⁎ a Wallenberg Neuroscience Center, Department of Experimental Medical Science, Lund University, BMC A11, SE-221 84 Lund, Sweden b Lund Strategic Center for Stem Cell Biology and Cell Therapy, Lund University, BMC A11, SE-
Strengths and limitations of the neurosphere culture system The Neurosphere Culture System Various methods with slight variations in protocol exist for establishing and expanding neurosphere cultures. Generally, neurospheres are derived from a single-cell suspension of neural stem and progenitor cells isolated from the adult or fetal central nervous system (CNS), but neurosphere cultures can also
doi:10.1016/S1044-7431(03)00097-6 A transplantation study of expanded human embryonic forebrain precursors: evidence for selection of a specific progenitor population Malin Parmar,* Charlotta Skogh, and Ulrica Englund1 Wallenberg Neuroscience Center, BMC A11, Section of Neurobiology, Lund University, SE-221 84 Lund, Sweden Received 2 January 2003; revised 12 March 2003; accepted 17 March 2003 Abst
The future of stem cell therapies for Parkinson disease Parkinson disease (PD) is a progressive neurodegen- erative disorder that is characterized by relatively focal degeneration of mesencephalic dopamine (mesDA) neurons, the cell bodies of which are located within the substantia nigra pars compacta in the ventral mes- encephalon (VM)1. The associated loss of axonal pro- jections and subsequent d
Human iPS cell-derived dopaminergic neurons function in a primate Parkinson’s disease model 5 9 2 | N A T U R E | V O L 5 4 8 | 3 1 A U g U s T 2 0 1 7 LETTER doi:10.1038/nature23664 Human iPS cell-derived dopaminergic neurons function in a primate Parkinson’s disease model Tetsuhiro Kikuchi1, Asuka Morizane1, Daisuke Doi1, Hiroaki Magotani1, Hirotaka Onoe2, Takuya Hayashi2, Hiroshi Mizuma2, sayuk
https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_nature_0.pdf - 2025-05-10
pnas201311187 4375..4384 Region-specific restoration of striatal synaptic plasticity by dopamine grafts in experimental parkinsonism Daniella Rylandera,b, Vincenza Bagettab, Valentina Pendolinob, Elisa Ziannic, Shane Grealishd, Fabrizio Gardonic, Monica Di Lucac, Paolo Calabresib,e, M. Angela Cencia, and Barbara Picconib,1 aBasal Ganglia Pathophysiological Unit, Lund University, BMC F11, 22184 Lun
https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_pnas.pdf - 2025-05-10
White Paper For reprint orders, please contact: reprints@futuremedicine.com Stem cell culture conditions and stability: a joint workshop of the PluriMes Consortium and Pluripotent Stem Cell Platform Glyn N Stacey*,1, Peter W Andrews2, Ivana Barbaric2, Charlotta Boiers3,4, Amit Chandra5, Giulio Cossu6, Lynn Csontos7, Thomas JR Frith2, Jason A Halliwell2, Zoe Hewitt2, Mark McCall8, Harry D Moore2, M
https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_regen_med.pdf - 2025-05-10
Research Article Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus Natalia Avaliani,1 Ulrich Pfisterer,2 Andreas Heuer,2,3 Malin Parmar,2 Merab Kokaia,1 and My Andersson1 1Epilepsy Centre, Lund University Hospital, Lund, Sweden 2Developmental Neurobiology, Lund University, Lund, Sweden 3Molecular Neuromodulation, Lund University, Lund, S
314 Translational Neuroscience Review Article • DOI: 10.2478/s13380-012-0041-x • Translational Neuroscience • 3(4) • 2012 • 314-319 E-mail: *agnete.kirkeby@med.lu.se #malin.parmar@med.lu.se Cell replacement for neurodegenerative diseases Cell replacement strategies, designed to substitute lost neurons by implantation of new functional cells, is a promising therapy for neurodegenerative diseases. F
Journal of Visualized Experiments www.jove.com Copyright © 2018 Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License February 2018 | 132 | e56904 | Page 1 of 8 Video Article Simple Generation of a High Yield Culture of Induced Neurons from Human Adult Skin Fibroblasts Shelby Shrigley1, Karolina Pircs1, Roger A. Barker1,2, Malin Parmar1, Janelle Drouin-Ouellet1 1Department of Ex
https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/shrigley.pdf - 2025-05-10
doi:10.1016/j.expneurol.2005.11.025 Neurogenin2 identifies a transplantable dopamine neuron precursor in the developing ventral mesencephalon Lachlan H. Thompson a,1, Elin Andersson a,1, Josephine B. Jensen a, Perrine Barraud a, Francois Guillemot b, Malin Parmar a, Anders Björklund a,⁎ a Wallenberg Neuroscience Center, Department of Experimental Medical Science, and Lund Strategic Center for Stem
