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Reflection on modern methods: visualizing the effects of collinearity in distributed lag models

Collinearity can be a problem in regression models. When examining the effects of an exposure at different time points, constrained distributed lag models can alleviate some of the problems caused by collinearity. Still, some consequences of collinearity may remain and they are often unexplored. We aimed to illustrate the effects of collinearity in the context of distributed lag models, and to pro

https://www.lupop.lu.se/article/reflection-modern-methods-visualizing-effects-collinearity-distributed-lag-models - 2025-10-01

Reflection on modern methods: statistical, policy and ethical implications of using age-standardized health indicators to quantify inequities

Methods for calculating health indicators profoundly influence understanding of and action on population health and inequities. Age-standardization can be useful and is commonly applied to account for differences in age structures when comparing health indicators across groups. Age-standardized rates have well-acknowledged limitations, including that they are relative indices for comparison, and n

https://www.lupop.lu.se/article/reflection-modern-methods-statistical-policy-and-ethical-implications-using-age-standardized-health - 2025-10-01

Reflection on modern methods: combining weights for confounding and missing data

Inverse probability weights are increasingly used in epidemiological analysis, and estimation and application of weights to address a single bias are well discussed in the literature. Weights to address multiple biases simultaneously (i.e. a combination of weights) have almost exclusively been discussed related to marginal structural models in longitudinal settings where treatment weights (estimat

https://www.lupop.lu.se/article/reflection-modern-methods-combining-weights-confounding-and-missing-data - 2025-10-01

The Case for Case–Cohort: An Applied Epidemiologist’s Guide to Reframing Case–Cohort Studies to Improve Usability and Flexibility

When research questions require the use of precious samples, expensive assays or equipment, or labor-intensive data collection or analysis, nested case–control or case–cohort sampling of observational cohort study participants can often reduce costs. These study designs have similar statistical precision for addressing a singular research question, but case–cohort studies have broader efficiency a

https://www.lupop.lu.se/article/case-case-cohort-applied-epidemiologists-guide-reframing-case-cohort-studies-improve-usability-and - 2025-10-01

A Flexible Statistical Framework for Estimating Excess Mortality

Quantifying the impact of natural disasters or epidemics is critical for guiding policy decisions and interventions. When the effects of an event are long-lasting and difficult to detect in the short term, the accumulated effects can be devastating. Mortality is one of the most reliably measured health outcomes, partly due to its unambiguous definition. As a result, excess mortality estimates are

https://www.lupop.lu.se/article/flexible-statistical-framework-estimating-excess-mortality - 2025-10-01

Three researchers receive Barncancerfonden funding to investigate the causes of childhood leukemia

Each year, around 350 children in Sweden are diagnosed with cancer. Thanks to progress in research and treatment, six out of seven children today survive. But unlike cancer in adults, we don't know what causes most childhood cancers to develop. This spring Barncancerfonden, the Swedish Childhood Cancer Foundation, awarded SEK 64 million to 29 researchers across the country. The funding includes po

https://www.stemcellcenter.lu.se/article/three-researchers-receive-barncancerfonden-funding-investigate-causes-childhood-leukemia - 2025-10-01

Paul Bourgine awarded ERC Proof of Concept grant

Paul Bourgine, research group leader at Lund University's Lund Stem Cell Center, has been awarded an ERC Proof of Concept grant for his project CiThOss – Cellular immunoTHERapy modelling by exploitation of humanized OSSicles, which aims to develop accurate models for testing immunotherapies in cancer treatment. The European Research Council's Proof of Concept is awarded to researchers to investiga

https://www.stemcellcenter.lu.se/article/paul-bourgine-awarded-erc-proof-concept-grant - 2025-10-01

Why repetitive DNA matters for human brain evolution and disease

For decades, large stretches of human DNA were dismissed as ‘junk’ and considered to serve no real purpose. In a new study in Cell Genomics, researchers at Lund University in Sweden show that the repetitive part of the human genome plays an active role during early brain development and may also be relevant for understanding brain diseases. DNA carries the complete set of instructions an organism

https://www.stemcellcenter.lu.se/article/why-repetitive-dna-matters-human-brain-evolution-and-disease - 2025-10-01

Hjelt Diabetes Foundation supports research that can pave the way for new cell therapies

Type 2 diabetes is a chronic disease that usually requires lifelong treatment. A central goal for many diabetes researchers is to develop new cell therapies that can cure the disease. The Bo and Kerstin Hjelt Diabetes Foundation now provides support two diabetes researchers at Lund University working to learn more about diabetes. Among them is Associate Professor Isabella Artner, from the Lund Uni

https://www.stemcellcenter.lu.se/article/hjelt-diabetes-foundation-supports-research-can-pave-way-new-cell-therapies - 2025-10-01

Scientists uncover cellular “toolkit” to reprogram immune cells for cancer therapy

An international team led by researchers at Lund University in Sweden has identified the molecular tools needed to reprogram ordinary cells into specialised immune cells. The discovery, published in Immunity, could pave the way for more precise and personalised cancer immunotherapies. The team has taken an important step toward harnessing the immune system to fight cancer. Their work describes how

https://www.stemcellcenter.lu.se/article/scientists-uncover-cellular-toolkit-reprogram-immune-cells-cancer-therapy - 2025-10-01

ERC grant awarded to explore how the immune system shapes fertility

Why do some pregnancies succeed while others do not? With support from a newly awarded ERC Starting Grant, Assistant Professor Camila Consiglio and her team at Lund University’s Lund Stem Cell Center are embarking on a project to explore the role the immune system plays in fertility, and in determining reproductive success. Infertility is a deeply personal and global health issue, affecting one in

https://www.stemcellcenter.lu.se/article/erc-grant-awarded-explore-how-immune-system-shapes-fertility - 2025-10-01

Celebrating the art in science: Images from the 2025 Image Competition

The Lund Stem Cell Center’s Annual Image Competition returned this year with another vibrant display of creativity, curiosity, and scientific discovery. From intricate cellular landscapes to artistic interpretations of research, this year’s submissions once again highlighted the diverse and inspiring work of our research community. Now in its fourth year, the Lund Stem Cell Center Annual Image Com

https://www.stemcellcenter.lu.se/article/celebrating-art-science-images-2025-image-competition - 2025-10-01

Talk on climate change and river disputes in South Asia

On Tuesday October 9 at 11-13 Professor Ashok Swain i will give a talk on climate change and river disputes in South Asia at : LUMES Josephson - Room Maathai (3rd floor). Ashok Swain is a Professor of Peace and Conflict Research, UNESCO Chair of International Water Cooperation, and the Director of Research School of International Water Cooperation at Uppsala University, Sweden. He received his Ph.

https://www.sasnet.lu.se/article/talk-climate-change-and-river-disputes-south-asia - 2025-10-01

TISS workshop report

During the final week of September, 2018, the School of Social Work, Lund University, hosted a group of researchers from the School of Social Work at Tata Institute of Social Sciences (TISS) in Mumbai, India. Already established as partners in teaching and education the schools want to move ahead and collaborate in research as well. The purpose of the Indian visit was to get to know researchers in

https://www.sasnet.lu.se/article/tiss-workshop-report - 2025-10-01

SASNET visited the University of Chicago and the 47th Annual Conference on South Asia in Madison

SASNET director Andreas Johansson and SASNET researcher Admir Skodo attended the 47th Annual Conference on South Asia in Madison, Wisconsin and presented their work in meetings and panels. The conference saw the participation of over 1,000 scholars, students, and professionals in a three-day event featuring research panels, round tables, lectures, performances and film screenings. The conference h

https://www.sasnet.lu.se/article/sasnet-visited-university-chicago-and-47th-annual-conference-south-asia-madison - 2025-10-01

Panel on Hindu Nationalism

On Wednesday 31 October 16.00-18.00 in room R240, Gamla kirurgen 2nd floor, Sandgatan a panel on Hindu nationalism will address the particular narratives and discourses of populist politics in India in the light of neoliberal politics and globalization. The speakers will focus on how rightwing populist narratives of nativism, religion, tradition, and gender have affected and influenced discriminat

https://www.sasnet.lu.se/article/panel-hindu-nationalism - 2025-10-01

SASNET researcher presented a paper at the international Refugees, Borders and Membership Conference

SASNET researcher Admir Skodo presented a paper entitled "The internationalized state and conflicts: The Afghan diaspora and Afghan statebuilding since 1979" at the international Refugees, Borders and Membership Conference, held at Malmö University October 24-26. Read more about the conference here. 

https://www.sasnet.lu.se/article/sasnet-researcher-presented-paper-international-refugees-borders-and-membership-conference - 2025-10-01