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Our previous data-driven analysis of evolving patterns of islet autoantibodies (IAbs) against insulin (IAA), glutamic acid decarboxylase (GADA) and islet antigen 2 (IA-2A) discovered three trajectories characterized by either multiple IAbs (TR1), IAA (TR2), or GADA (TR3) as the first appearing autoantibodies. Here we examined the evolution of IAb levels within these trajectories in 2,145 IAb-posit
The implementation of circular initiatives requires certain capabilities and knowledge that traditional business models often lack, requiring new perspectives and external collaborations. While it is understood that partnerships can aid in innovation and provide knowledge and capabilities to firms, the dynamics of collaboration for the transition towards circular business models (CBMs) need to be
When the politically active Ukrainian community in Edmonton, Alberta, gathered in late November 2019 for their annual commemorations of the massive famine that ravished the Ukrainian Soviet Republic in 1932–33, their rituals followed established patterns. The politically well-connected Ukrainian Canadian Congress (UCC) held its choreographed gatherings in the
Excerpt: "Just like the rest of the population, Swedish Christians remain fundamentally divided in their opinions about the best way to arrange Sweden’s relationship to NATO. But the responses on the part of the churches also seem to hark back to bygone ages. National defense and foreign policy remain, in a country for centuries fundamentally shaped by Lutheran doctrine concerning the division bet
Dose-response association between level of impairment of semen quality and risk of morbidity or premature death has been reported. Therefore, it can be presumed that men utilizing donated spermatozoa, i.e. patients with non-obstructive azoospermia, are at highest risk for adverse health outcomes. To evaluate the risks of prescription of medications for common metabolic disturbances and testosteron
Under what conditions do firms in buyer-supplier relationships learn to contract? Contract design capabilities are typically understood as a function of the contractual problems faced by firms. However, a firms’ learning to contract is also likely affected by the organizational and institutional conditions in which contracts are entered. Based on five inductive case studies of buyer-supplier relat
BACKGROUND: Postural orthostatic tachycardia syndrome (POTS) is a common cardiovascular autonomic disorder characterized by excessive heart rate (HR) increase on standing and symptoms of orthostatic intolerance, posing significant limitations on functional capacity. No objective tool exists to classify symptom burden in POTS.METHODS: We conducted a case-control study in 62 POTS patients and 50 hea
Objectives: To examine potential sex differences in longitudinal cognitive and activities of daily living (ADL) performance and life expectancy between early- and late-onset Alzheimer’s disease (AD). Methods: The Swedish Alzheimer Treatment Study is a prospective, observational, multicentre study that was used in a routine clinical setting including 1,017 patients diagnosed with mild-to-moderate A
The lifetimes of the terms 3p2P, 3d2D, 4s2S, 4p2P, 4d2D, 4f2F, 5g2G, 6g2G, 6h2H, 7h2H, 7i2I and 8k2K in sodiumlike sulfur, S VI, have been determined using the beam-foil excitation technique. Most of the decay curves were analyzed by means of the ANDC method which corrects for cascading in a very detailed way. Accurate results were thereby obtained which show that an excellent agreement exists bet
The spectrum emitted from a nickel hollow cathode has been recorded with a Fourier transform spectrometer. Two dense groups of lines just above 18 000 Å have been identified as the transitions 3d8 (3F)5f-3d8 (3F)6g and 3d8 (3F)5g-3d8 (3F)6h in Ni II. The level structure of the configurations involved in these transitions has been studied by fitting the Slater parameters of the energy matrices to t
Direct neuronal reprogramming of a somatic cell into therapeutic neurons, without a transient pluripotent state, provides new promise for the large number of individuals afflicted by neurodegenerative diseases or brain injury. This approach could be potentially applied directly in the brain by targeting resident cells as a source of new neurons. Direct neuronal conversion of resident glial cells i
Interviews where photographs taken by the respondent are used in order to stimulate the conversation and to gain rich empirical material are increasingly employed by researchers. The ubiquitous use of mobile cameras and digital platforms such as Instagram has made it easier for the researcher as well as for the interviewees to take and share photographs. The limitations of participatory visual metInterviews where photographs taken by the respondent are used in order to stimulate the conversation and to gain rich empirical material are increasingly employed by researchers. The ubiquitous use of mobile cameras and digital platforms such as Instagram has made it easier for the researcher as well as for the interviewees to take and share photographs. The limitations of participatory visual met
As legislators and platforms tackle the challenge of suppressing hate speech online, questions about its definition remain unresolved. In this review we discuss three issues: What are the main challenges encountered when defining hate speech? What alternatives are there for the definition of hate speech? What is the relationship between the nature and scope of the definition and its operationabili
