Background: The assessment of left ventricular (LV) filling pressure in heart failure (HF) poses a diagnostic challenge, as HF patients may have normal LV filling pressures at rest but often display elevated LV filling pressures during exercise. Rapid preload increase during passive leg lift (PLL) may unmask HF in such challenging scenarios. We explored the dynamic interplay between simultaneous l

The existence of superconductivity (SC) appears to be established in both twisted and nontwisted graphene multilayers. However, whether their building block, single-layer graphene (SLG), can also host SC remains an open question. Earlier theoretical works predicted that SLG could become a chiral d-wave superconductor driven by electronic interactions when doped to its van Hove singularity, but que

We uncover a critical side-channel vulnerability in the Hamming Quasi-Cyclic (HQC) round 4 optimized implementation arising due to the use of the modulo operator. In some cases, compilers optimize uses of the modulo operator with compiletime known divisors into constant-time Barrett reductions. However, this optimization is not guaranteed: for example, when a modulo operation is used in a loop the

The first issue of Journal for Person-Oriented Research (JPOR) was published in 2015, representing the first international journal specifically focused on person-oriented research. With this issue, the JPOR completes its tenth yearly volume. The status of JPOR as a truly international journal is reflected in the number of published articles from different countries. The number of submissions to JP

Background: Effective prehospital care for acute chest pain critically relies on ambulance nurses’ adherence to clinical guidelines. However, current adherence is inadequate, with no instruments available to improve the situation. Therefore, this study aimed to develop and psychometrically evaluate an instrument measuring ambulance nurses’ adherence to and attitudes towards acute chest pain guidel

Adipose-derived lipid droplets (LDs) are rich in triacylglycerols (TAGs), which regulate essential cellular processes, such as energy storage. Although TAG accumulation and LD expansion in adipocytes occur during obesity, how LDs dynamically package TAGs in response to excessive nutrients remains elusive. Here, we found that LD lipidomes display a remarkable increase in TAG acyl chain saturation u

PURPOSE: The purpose of this study was to examine the psychometric properties of the Swedish short form of the Speech, Spatial and Qualities of Hearing Scale (SSQ12) and investigate whether the paper-and-pen and online formats could be used interchangeably. METHOD: Individuals with and without hearing problems were invited to participate in this study. The participants (N = 125) were randomized in

This paper presents the results of the 2022 Groundwater Time Series Modelling Challenge, where 15 teams from different institutes applied various data-driven models to simulate hydraulic-head time series at four monitoring wells. Three of the wells were located in Europe and one was located in the USA in different hydrogeological settings in temperate, continental, or subarctic climates. Participa

This paper examines the intersection of peace, justice and sustainability by exploring thepotential of international criminal law to contribute to environmental peacebuilding goals,which include sustainable governance of natural resources and cooperation to establishlasting peaceful relations within and between States. Despite the merits of existing stud-ies in shedding light on the concept of env

Course leaders in rehabilitation healthcare professionals’ higher education face challenges stemming from multi-disciplinarity and the co-existence of different stakeholders. So far, the literature mainly attributed to course leaders’ managerial tasks, neglecting other fundamental transversal skills. Students represent an essential source of information for understanding the expected characteristi

Midbrain dopaminergic neurons exhibit a wide diversity in their projection patterns, disease vulnerability, and functions, playing key roles in voluntary motor control, cognition, and reward processing. Parkinson’s Disease, one of the most common neurodegenerative disorders, is characterized by the selective degeneration of the A9 dopaminergic neuron subtype, leading to severe motor dysfunction. D

Hematopoietic stem cells (HSCs) cultured outside the body are the fundamental component of a wide range of cellular and gene therapies. Recent efforts have achieved > 200-fold expansion of functional HSCs, but their molecular characterization has not been possible since the majority of cells are non-HSCs and single cell-initiated cultures have substantial clone-to-clone variability. Using the Fgd5

One of the most challenging aspects of stem cell research is the reliance on retrospective assays for ascribing function. This is especially problematic for hematopoietic stem cell (HSC) research in which the current functional assay that formally establishes its HSC identity involves long-term serial transplantation assays that necessitate the destruction of the initial cell state many months bef

Haematopoietic stem cell (HSC) self-renewal is a process that is essential for the development and homeostasis of the blood system. Self-renewal expansion divisions, which create two daughter HSCs from a single parent HSC, can be harnessed to create large numbers of HSCs for a wide range of cell and gene therapies, but the same process is also a driver of the abnormal expansion of HSCs in diseases

An increasingly large part of the population in the West identifies as religious Nones. Contrary to what might be assumed, most of them are not outright atheists. They reject traditional religion, but many pursue different forms of spirituality, and many entertain supernatural ideas. This element concerns the worldview of these “semi-secular” Nones. When asked about whether they believe in God, th

This study explores Buddhist monks’ views on the religion-science relationship in contemporary China. Drawing on survey data, interviews with monks, and participant observation within Shaolin Temple – famous for its antiquity and its export of Shaolin Kungfu – we discern and theoretically account for two forms of ‘non-conflict,’ between science and religion, that shape monks’ mental lives. One gro

Denna artikel analyserar Jessica Schiefauers spekulativa roman Bärarna (2020) och diskuterar konsekvenserna av att bygga ett samhälle utifrån smittoprevention. Romanen skildrar en framtid där en rabiesliknande sjukdom hotat att utplåna mänskligheten. I denna dystopi har män, som spridare av smittan, och kvinnor separerats för att förhindra återkomsten av sjukdomen. Artikeln undersöker hur romanen This article analyses Jessica Schiefauer’s speculative novel Bärarna (2020), and examines the consequences of building a society based on disease pre-vention. The novel depicts a future where a rabies-like disease has nearly wiped out humanity. In this dystopia, men, as carriers of the disease, are separated from women to prevent the resurgence of the illness. The article investigates how the nove