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Refugee housing in rural Finland and Sweden

This paper discusses how housing for refugees is delt with by the authorities in rural Finland and Sweden. More precisely, we look at the services systems, rights and obligations which guide the choices of immigrants once they are allowed so stay, at least temporarily, in respective country. We apply the ‘conflicted policy processes’ approach in intergovernmental relations and Peter Scholten’s gov

Effect of acidosis on adipose-derived stem cell impairment and gene expression

Based on disappointing results of stem cell-based application in clinical trials for patients with critical limb ischemia, we hypothesized that the acidic environment might be the key factor limiting cell survival and function. In the present study, we used microdialysis to determine presence of acidosis and metabolic imbalance in critical ischemia. Moreover, we explored the effect of extracellula

Shifts in microbial community composition and metabolism correspond with rapid soil carbon accumulation in response to 20 years of simulated nitrogen deposition

Anthropogenic nitrogen (N) deposition and fertilization in boreal forests frequently reduces decomposition and soil respiration and enhances C storage in the topsoil. This enhancement of the C sink can be as strong as the aboveground biomass response to N additions and has implications for the global C cycle, but the mechanisms remain elusive. We hypothesized that this effect would be associated w

Circular Definitions of ‘Good’ and the Good of Circular Definitions

I defend the view that circular definitions can be useful and illuminating by focusing on the fitting-attitudes analysis of value. This definition states that an item has value if and only if it is a fitting target of attitudes. Good items are the fitting targets of positive attitudes, and bad items are the fitting targets of negative ones. I shall argue that a circular version of this definition,

Improving glacio-hydrological model calibration and model performance in cold regions using satellite snow cover data

Hydrological modeling realism is a central research question in hydrological studies. However, it is still a common practice to calibrate hydrological models using streamflow as a single hydrological variable, which can lead to large parameter uncertainty in hydrological simulations. To address this issue, this study employed a multi-variable calibration framework to reduce parameter uncertainty i

Transfer RNA modifications and modifying enzymes in Saccharomyces cerevisiae

Transfer RNAs are adaptor molecules, which decode mRNA into protein and,thereby, play a central role in gene expression. During the maturation of a primarytRNA transcript, specific subsets of the four normal nucleosides adenosine,cytidine, guanosine, and uridine are modified. The formation of a modified nucleosidecan require more than one gene product and may involve several enzymaticsteps. In the

Steady-State Calculation vs. Dynamic Energy Simulations during the Early Design Phase

This article uses the steady-state calculation, based on the heating degree-day method, to verify dynamicenergy simulations and estimate a building's heating energy use in early design phases. Utilizing ClimateStudio through Rhinoceros/Grasshopper, this method acts as a control, ensuring reliability of the dynamicmodel's input/output. The simulations were conducted on a single building block with

BioMEL : a translational research biobank of melanocytic lesions and melanoma

Introduction Diagnosing invasive cutaneous melanoma (CM) can be challenging due to subjectivity in distinguishing equivocal nevi, melanoma in situ and thin CMs. The underlying molecular mechanisms of progression from nevus to melanoma must be better understood. Identifying biomarkers for treatment response, diagnostics and prognostics is crucial. Using biomedical data from biobanks and population-

Rise and fall of the giants? : Innovating firms in Sweden, 1890-2016

This study investigates patterns of innovation during two successive industrial revolutions in Sweden. “Genius engineering firms”, such as L M Ericsson, SKF and ASEA (ABB) have dominated narratives about Sweden’s industrial and innovation success. Using new long-term data series of innovation output, 1890-2016, we observe several patterns. First, we document inverted U-shaped patterns during the c

New Antidiabetic Agents for the Treatment of Heart Failure in Hypertensive Patients

The development of newer glucose-lowering drugs for the treatment of type 2 diabetes in recent years, such as the SGLT-2 inhibitors and GLP-1 receptor agonists/analogues with well-documented clinical benefits from large trials, has influenced international guidelines. These drugs are able to reduce both macro- and microvascular events in patients with type 2 diabetes and to prevent worsening of di

Chronic widespread pain and cause of death : a 25-year follow-up study

Introduction:Chronic widespread pain (CWP) has been suggested as a risk factor for mortality in cardiovascular diseases and malignancies. Different definition of CWP makes it difficult to compare previous studies.Objectives:The aim was to study whether mortality and certain causes of death were increased among people with CWP and whether the definition of CWP influenced outcome.Methods:This 25-yea

Germination and stress tolerance of oats treated with pulsed electric field at different phases of seedling growth

This study explores the impact of pulsed electric field (PEF) application on oat seedling growth and stress tolerance. PEF treatment (99 monopolar, rectangular pulses lasting 10 µs each, with a frequency of 13 Hz and a nominal electric field strength of 2250 V/cm) was applied at two growth stages: (i) when the seedlings had 0.2 cm roots emerging from the kernel, and (ii) when they had a 0.4 cm sho

High cell density sequential batch fermentation for enhanced propionic acid production from glucose and glycerol/glucose mixture using Acidipropionibacterium acidipropionici

Background: Propionic acid fermentation from renewable feedstock suffers from low volumetric productivity and final product concentration, which limits the industrial feasibility of the microbial route. High cell density fermentation techniques overcome these limitations. Here, propionic acid (PA) production from glucose and a crude glycerol/glucose mixture was evaluated using Acidipropionibacteri

Synthesis of Homo- and Copolyesters Using an AB-Type Aromatic Monomer Based on Homovanillic Acid

There is currently intensive research ongoing with the aim to utilize various lignin-derived molecules to produce aromatic monomers and polymers. In the present work, homovanillic acid (HVA), derived from lignin, was used to prepare sustainable polyesters for the first time. An AB-type monomer with an alcohol group and a carboxylate ester group was conveniently synthesized by using HVA and et

T-cell commitment inheritance—an agent-based multi-scale model

T-cell development provides an excellent model system for studying lineage commitment from a multipotent progenitor. The intrathymic development process has been thoroughly studied. The molecular circuitry controlling it has been dissected and the necessary steps like programmed shut off of progenitor genes and T-cell genes upregulation have been revealed. However, the exact timing between decisio

Transport and retention of functionalized graphene oxide nanoparticles in saturated/unsaturated porous media : Effects of flow velocity, ionic strength and initial particle concentration

The widespread use of nanomaterials has raised the threat of nanoparticles (NPs) infection of soils and groundwater resources. This research aims to investigate three parameters including flow velocity, ionic strength (IS), and initial particle concentration effects on transport behavior and retention mechanism of functionalization form of graphene oxide with polyvinylpyrrolidone (GO-PVP). The tra