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Associations of age, BMI, and renal function to cortisol after dexamethasone suppression in patients with adrenal incidentalomas

Introduction: The specificity of cortisol after 1 mg dexamethasone (cortisolDST) ≥50 nmol/L as a criterion for mild autonomous cortisol secretion (MACS) is approximately 85% in patients with adrenal incidentalomas (AI). The aim was to study the associations of cortisolDST to age, BMI, and renal function. Methods: We studied 1,129 patients with AI examined from 2005 to 2015 at Skåne University Hosp

Three new species of Valeriana (Valerianoideae, Caprifoliaceae) from southern Ecuador

Three new species of Valeriana from southern Ecuador are described and illustrated. Valeriana plateadensis is found near the highest peak of Cerro Plateado in Cordillera del Cóndor at 2900 m a.s.l. and is recognized by the shrubby habit and sessile, densely imbricate, spatulate leaves and 3-lobed corollas. V. yacuriensis is found near Lagunas Negras de Jimbura in the Parque Nacional Yacurí at 3500

Prognostic Value of Early Sustained Ventricular Arrhythmias in ST-Segment Elevation Myocardial Infarction Treated by Primary Percutaneous Coronary Intervention : A Substudy of VALIDATE-SWEDEHEART Trial

Background: Prognostic assessment of ventricular tachycardia (VT) or ventricular fibrillation (VF) in ST-segment elevation myocardial infarction (STEMI) is based mainly on distinguishing between early (<48 hours) and late arrhythmias, and does not take into account its time distribution with regard to reperfusion, or type of arrhythmia. Objective: We analyzed the prognostic value of early ventricu

Can university leaders effectively promote research on complex societal challenges? : a change-agency perspective

In recent years, new expectations have been placed on universities, demanding academic contributions towards solving large-scale, interdisciplinary challenges. This is in conflict with existing insights from university governance research, which emphasises that scientific communities focus on reproducing disciplinary practices that are unsuitable in addressing societal challenges, because the prob

Digital corporate communication and hostile hijacking of organizational crises

Social media and digital communication not only provide ways for organisations to engage stakeholders in new and more dialogic ways but have also opened a historically unprecedented Pandora’s box of disinformation techniques. Conventional crisis communication is well prepared to engage critical stakeholders, but its routines are ill-adapted to exploitative actors who employ deceptive or malicious

Exploring child protection content in social work curricula in South Africa and Sweden

Child participation and agency are vital elements in child protec-tion. Ensuring child participation can contribute to successful inter-ventions. Social workers are often the central agents in ensuring that children participate in matters concerning them and that the best interest of the child principle is adhered to in these matters. The aim of this study is thus to understand if and how social w

The Influence of Treatment Latency on Suicide-Specific Treatment Outcomes

IntroductionThe Attempted Suicide Brief Intervention Program (ASSIP) provides an effective and cost-effective treatment option for people who have attempted suicide. Studies suggest that longer treatment latency is associated with poorer response to therapy, more severe symptomatology, and more suicide attempts This study examined the influence of treatment latency (time between suicide attempt an

Lung Fibroblasts from Chronic Obstructive Pulmonary Disease Subjects Have a Deficient Gene Expression Response to Cigarette Smoke Extract Compared to Healthy

BACKGROUND AND AIM: Cigarette smoking is the most common cause of chronic obstructive pulmonary disease (COPD) but more mechanistic studies are needed. Cigarette smoke extract (CSE) can elicit a strong response in many COPD-related cell types, but no studies have been performed in lung fibroblasts. Therefore, we aimed to investigate the effect of CSE on gene expression in lung fibroblasts from hea

The effect of electrode composition on bimetallic AgAu nanoparticles produced by spark ablation

A flexible way to generate bimetallic nanoparticles with high control of their composition is to use spark ablation of alloyed electrodes. It has been generally accepted and stated that particles produced using spark ablation of alloyed electrodes obtain the same chemical composition as the electrodes. However, we identify a lack of studies fully supporting the connection between electrode and par

Temperature-Dependent Intensity Modulated Two-Photon Excited Fluorescence Microscopy for High Resolution Mapping of Charge Carrier Dynamics

We present a temperature-dependent intensity modulated two-photon excited fluorescence microscopy technique that enables high-resolution quantitative mapping of charge carrier dynamics in perovskite microcrystal film. By disentangling the emission into harmonics of the excitation modulation frequency, we analyze the first and second order charge carrier recombination processes, including potential

Policies on children and schools during the SARS-CoV-2 pandemic in Western Europe

During the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), mitigation policies for children have been a topic of considerable uncertainty and debate. Although some children have co-morbidities which increase their risk for severe coronavirus disease (COVID-19), and complications such as multisystem inflammatory syndrome and long COVID, most children only get mild C

Impact of different water penetration criteria and cavity ventilation rates on the risk of mold growth in timber frame walls with brick veneer cladding

The present paper investigates the impact of different water penetration criteria on the risk for damage in a common type of building envelope in Nordic countries, timber frame walls with brick masonry veneer. The studied walls are evaluated based on one damage criterion, the risk of mold growth. The study investigates several parameters: water penetration criterion, type of moisture source (unifo

Biofilm colonization and succession in a full-scale partial nitritation-anammox moving bed biofilm reactor

BACKGROUND: Partial nitritation-anammox (PNA) is a biological nitrogen removal process commonly used in wastewater treatment plants for the treatment of warm and nitrogen-rich sludge liquor from anaerobic digestion, often referred to as sidestream wastewater. In these systems, biofilms are frequently used to retain biomass with aerobic ammonia-oxidizing bacteria (AOB) and anammox bacteria, which t

Bivalirudin versus heparin in ST and non-ST-segment elevation myocardial infarction—Outcomes at two years

Background: The registry-based randomized VALIDATE-SWEDEHEART trial (NCT02311231) compared bivalirudin vs. heparin in patients undergoing percutaneous coronary intervention (PCI) for myocardial infarction (MI). It showed no difference in the composite primary endpoint of death, MI, or major bleeding at 180 days. Here, we report outcomes at two years. Methods: Analysis of primary and secondary endp

Very little influenza in the WHO European Region during the 2020/21 season, weeks 40 2020 to 8 2021

Between weeks 40 2020 and 8 2021, the World Health Organization European Region experienced a 99.8% reduction in sentinel influenza virus positive detections (33/25,606 tested; 0.1%) relative to an average of 14,966/39,407 (38.0%; p < 0.001) over the same time in the previous six seasons. COVID-19 pandemic public health and physical distancing measures may have extinguished the 2020/21 European se

Association of Maternal SARS-CoV-2 Infection in Pregnancy With Neonatal Outcomes

IMPORTANCE: The outcomes of newborn infants of women testing positive for SARS-CoV-2 in pregnancy is unclear.OBJECTIVE: To evaluate neonatal outcomes in relation to maternal SARS-CoV-2 test positivity in pregnancy.DESIGN, SETTING, AND PARTICIPANTS: Nationwide, prospective cohort study based on linkage of the Swedish Pregnancy Register, the Neonatal Quality Register, and the Register for Communicab

Det oumbärliga klassrummet : en framställning på kognitionsvetenskaplig grund

Det oumbärliga klassrummet – en framställning på kognitionsvetenskaplig grund är en bok med grundskolans klassrum, elever och lärare i fokus. Det är också en bok om vilka former av kunnande som är nödvändiga att en ung människa får med sig från skolan.Framställningen har kognitionsvetenskaplig grund och förhåller sig genomgående till grundskolans syfte: att stödja barn och unga i deras vuxenblivan

Folkskolereformen 1842 : Skolgång för alla leder till kunskapslyft

Folkskolereformen 1842. De flesta kunde lära tidigare men inte skriva. Folkskolans införande visade att staten tog ansvar för en folkundervisning som omfattade alla barn. Dock fanns parallella skolstydem till mitten av 1900-talet, beroende på social klasstillhörighet.

Stateless Studies in an Age of Artificial Intelligence : Challenges, Opportunities & Setting a Future Agenda

Since 2010,there has been enormous social and political hype around artificial intelligence (‘AI’) and how it has, and will, continue to impact society. This is not just puffery, and there is growing recognition across a range of fields that there is an urgent need to further explore the use, scope and impact of AI in relation to digital forms of citizenship and the datafication of societies. Conc