Filtyp
The transient receptor potential ankyrin subtype 1 protein (TRPA1) is a nonselective cation channel permeable to Ca(2+), Na(+), and K(+). TRPA1 is a promiscuous chemical nocisensor that is also involved in noxious cold and mechanical sensation. It is present in a subpopulation of Aδ- and C-fiber nociceptive sensory neurons as well as in other sensory cells including epithelial cells. In primary se
Exposure to aerosol nanoparticles has always been present in the evolution of humans, and thus has the human body developed ways of dealing with particles that enters the body. However with the emerging nanotech industry, new types of nanoparticles are being produced and used. Many of these particles have properties never seen before and this rise concern about how exposure to them might cause unw
The details of an experimental setup for gas phase atomic and molecular fluorescence measurements using synchrotron radiation are described in this article. The most significant part of the apparatus is an optical arrangement, which allows for simultaneous measurements of dispersed as well as total fluorescence intensity using an effusive gas jet and an inbuilt gas cell assembled in a convenient p
The relationship between the receptors for the Epstein-Barr virus (EBV) and the C3d fragment of complement was investigated at the molecular level. In the presence of cell-bound C3, virus binding was enhanced in EBV genome-carrying lines. An identical effect could be elicited by C3d at one-quarter the weight amount; C3b and methylamine-treated C3 had no effect on virus binding. The minimum concent
Introduction: Individuals with severe alpha-1-antitrypsin (AAT) deficiency have a well-known risk of developing emphysema but it is not known at which age the first symptoms occur and lung function declines. The aim of this study was to examine the prevalence of smoking, respiratory symptoms and lung function at the age of 30 in AAT-deficient individuals (PiZ and PiSZ) identified by neonatal scree
A comparative analysis of the electron-hole (e-h) excitation mechanism of impurity luminescence has been performed for wide-gap oxides (WGO) and alkali halides crystals (AHC). A low quantum yield of scintillation in WGO with respect to that in AHC is connected with the high value of the average energy needed for the creation of an e-h pair in WGO. In AHC and many WGO, the width of a valence band E
A coordinated movement is easy to recognize, but we know little about how it is achieved. In search of the neural basis of coordination, we present a model of spinocerebellar interactions in which the structure-functional organizing principle is a division of the cerebellum into discrete microcomplexes. Each microcomplex is the recipient of a specific motor error signal-that is, a signal that conv
Poly(propylene oxide)s with a comblike architecture were prepared by using an ethylene-vinyl alcohol copolymer as a macroinitiator for anionic graft polymerisation of propylene oxide. The densely grafted polymers were subsequently modified by capping the terminal hydroxyl groups with hexadecanoyl chloride to produce aggregating polymers. Dilute solution viscometry showed that the hydroxyl and hexa
An eagerly awaited prostate cancer susceptibility gene has been announced. But does the candidate live up to expectations?
