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We report growth optimization of Nitrogen (N)-polar GaN epitaxial layers by hot-wall metal–organic vapor phase epitaxy on 4H-SiC (000) with a misorientation angle of 4° towards the [110] direction. We find that when using a 2-step temperature process for the N-polar GaN growth, step bunching is persistent for a wide range of growth rates (7 nm/min to 49 nm/min) and V/III ratios (251 to 3774). This
Nitrogen-polar III-nitride heterostructures offer advantages over metal-polar structures in high frequency and high power applications. However, polarity control in III-nitrides is difficult to achieve as a result of unintentional polarity inversion domains (IDs). Herein, we present a comprehensive structural investigation with both atomic detail and thermodynamic analysis of the polarity evol
BACKGROUND: Elevated pulmonary vascular resistance (PVR) in the setting of left heart failure may contribute to poor outcomes after pediatric heart transplant (HTx), but peri-transplant management is variable.METHODS: We sought to characterize international practice by surveying physicians at pediatric HTx centers.RESULTS: We received 49 complete responses from 39 centers in 16 countries. Most res
Climate change is expected to alter the frequency and intensity of soil drying-rewetting (D/RW) and freezing-thawing (F/TW) events, with consequences for the activities of microorganisms. Although both D/RW and F/TW events cause respiration pulses from soil to the atmosphere, it remains unknown whether the underlying microbial control is similar. Recent work has revealed that soil microbial respon
A series of ether-free poly(p-terphenyl piperidinium)s carrying both cationic and zwitterionic groups were prepared and evaluated as anion-exchange membranes (AEMs). First, a zwitterionic monomer (zwPip) was synthesized by sulfoalkylation of N-methyl-4-piperidone (Pip) using 1,4-butane sultone. Pip and zwPip were then employed in superacid-mediated polyhydroxyalkylations with p-terphenyl to prepar
Punctuality is an important aspect of train operations, highly valued by passengers. Both Swedish and Norwegian railways have introduced frameworks to systematically improve punctuality in their systems, inspired by an extensive literature on Total Quality Management. After about a decade with these frameworks, we can see that punctuality has risen by about 2-3 percentage points. However, this pac
Due to the rise in the demand for semi-dairy beverages (vegetable fat in a de-fatted dairy matrix) as well as for fully plant-based formulations, there is a growing interest in better understanding how emulsification processes are influenced by raw material choices. Semi-dairy beverages, for example, utilize a wide variety of vegetable oils in their formulation. This contribution combines traditio
Conditions involving intracranial vascular anomalies are increasingly diagnosed, not least incidentally, with the increasing availability of neuroradiological investigations. Acute deterioration and development of symptoms due to a vascular condition could require neurosurgical intervention depending on the nature of the condition and status of the patient. On the other hand, asymptomatic patients
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, in which prognosis is determined by liver fibrosis. A common variant in hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13, rs72613567-A) is associated with a reduced risk of fibrosis in NAFLD, but the underlying mechanism(s) remains unclear. We investigated the effects of this variant in the human liver and in Hsd17
Inducible defences allow prey to increase survival chances when predators are present while avoiding unnecessary costs in their absence. Many studies report considerable inter-individual variation in inducible defence expression, yet what underlies this variation is poorly understood. A classic vertebrate example of a predator-induced morphological defence is the increased body depth in crucian ca
The protein homeostasis network ensures a proper balance between synthesis, folding, and degradation of all cellular proteins. DnaK and trigger factor (TF) are ubiquitous bacterial molecular chaperones that assist in protein folding, as well as preventing protein misfolding and aggregation. In Escherichia coli, DnaK and TF possess partially overlapping functions. Their combined depletion results i
Efter flera år av snabba lagändringar på asylområdet kommer allt fler alarmerande rapporter om att människor på flykt, inte minst barn och unga, far illa efter att ha sökt asyl i Sverige. Därför bildas nu en granskningskommission för att undersöka vad det är som hänt och hur situationen kan förbättras.
Background: To evaluate the psychosocial consequences of surveillance with whole-body MRI (WB-MRI) in individuals with the heritable TP53-related cancer (hTP53rc) syndrome, also known as the Li-Fraumeni syndrome, with regard to cancer worry, perceived benefits and risks to surveillance and overall health. Patients and methods: Since 2016, the national Swedish TP53 Study (SWEP53) has offered survei
Background: The underlying factors of the male predominance in Autism Spectrum Disorders (ASD) are largely unknown, although a female advantage in social communication has been pointed out as a potential factor. Recently, attention has been given to ASD as a sensory processing disorder, focusing on the audio-visual temporal processing paramount for the development of communication. In ASD, a devia
Description of genetic phenomena and variations requires exact language and concepts. Vast amounts of variation data are produced with next-generation sequencing pipelines. The obtained variations are automatically annotated, e.g., for their functional consequences. These tools and pipelines, along with systematic nomenclature, mainly work well, but there are still some problems in nomenclature, o
