Filtyp
To investigate epigenetic patterns associated with aneuploidy we used constitutional trisomy 8 mosaicism (CT8M) as a model, enabling analyses of single cell clones, harboring either trisomy or disomy 8, from the same patient; this circumvents any bias introduced by using cells from unrelated, healthy individuals as controls. We profiled gene and miRNA expression as well as genome-wide and promoter
Problem: Niche co-evolution deals simultaneously with the number and the character of species within a community. How can a community of predators and prey adaptively radiate to fill available niches? How many niches are there? And, can adaptive speciation at evolutionary branching points successfully fill the niches of the ESS? Model features: We use a predator–prey model with one fitness-genera
Abstract in UndeterminedInconel 718, an efficient superalloy for energy and aerospace applications, is currently machined with cemented carbide tools at low speed (vc≈60 m/min) due to its unfavorable mechanical and thermal properties. The article presents results of a study of superalloy machinability with whisker reinforced alumina, uncoated and coated PCBN tools. Turning of age hardened Inconel
Protein S functions as a cofactor for tissue factor pathway inhibitor (TFPI) and activated protein C (APC). The sex hormone binding globulin (SHBG)-like region of protein S, consisting of two laminin G-like domains (LG1 and LG2), contains the binding site for C4b-binding protein (C4BP) and TFPI. Furthermore, the LG-domains are essential for the TFPI-cofactor function and for expression of full APC
An integrated system for the production of hydrogen by gasification of biomass and electrolysis of water has been designed and cost estimated. The electrolyser provides part of the hydrogen product as well as the oxygen required for the oxygen blown gasifier. The production cost was estimated to 39 SEK/kg H-2 at an annual production rate of 15 000 ton, assuming 10% interest rate and an economic li
More than a decade ago we published a calculation of nuclear ground-state masses and deformations in Atomic Data and Nuclear Data Tables [P. Moller, J.R. Nix, W.D. Myers, W.J. Swiatecki, At. Data Nucl. Data Tables 59 (1995) 185]. In this study, triaxial nuclear shapes were not considered. We have now enhanced our model and studied the influence of triaxial shape degrees of freedom on the nuclear g
We report the clinical feasibility of fluoroscopic Roentgen stereophotogrammetric analysis (FRSA), a validated method to quantify, real time three-dimensional (3D) dynamic motion of stent grafts and the first clinical results after abdominal and thoracic endovascular repair (EVAR). Stent graft motion was measured at 30 (stereo) frames per second, during the cardiac cycle and in the patient after a
Objective To determine coverage and generalisability of data in the Swedish Biologics Register ARTIS. Methods Patients with adult onset rheumatoid arthritis (RA) were identified in the National Patient Register and the Swedish Rheumatology Quality Register, including the ARTIS cohort of patients exposed to biological agents. Exposure to etanercept and adalimumab between 2006 and 2008 was determine
I den här artikeln argumenterar jag för att vårt tänkande i grunden är metafor- och föreställningsstyrt. Bilder och konceptuella ramverk styr i mångt och mycket hur vi kommunicerar, och därmed i grunden argumenterar och debatterar. Jag hävdar att det finns en utbredd föreställning om att vårt tänkande är mer objektivt förankrat än vad det egentligen är. Som rättssociolog är min poäng att det även
Nystedt recently gave a combinatorial proof of the fact that Ore extensions are associative. As part of it he proves that two sets of strings are identical, using a counting argument. We show that the equality of the sets can be proven directly. (C) 2013 Elsevier B.V. All rights reserved.
Changing Landscapes and Persistent Places is a study of the cultural landscape on the Bjäre peninsula in northwest Skåne. The many Bronze Age remains that give the landscape its distinctive character are the starting point for an attempt to increase our understanding of the historical depth of today’s landscape. The two perspectives of “landscape” and “places” carry the discussion forward, almost
Although in-situ conservation is increasingly considered an efficient way of conserving plant genetic resources, little is known about the incentives and constraints that govern conservation decisions among small farm holders in developing countries. Using a choice experiment approach, we investigated Ethiopian farmers' crop variety preferences, estimated the mean willingness to pay for each crop
We present a model for a feedback-controlled ratchet consisting of a Brownian particle and a moving, finite barrier that is shifted by an external agent depending on the position of the particle. By modifying the value of a single parameter of the feedback protocol, the model can act either as a pure rectifier, a power-stroke (PS) motor, or a combination of both. Interestingly, in certain situatio
The focus of this thesis is on KEL and JK, two clinically important blood group systems, and the investigations of blood samples with aberrant antigen expression as in null and weak phenotypes, or with a phenotype that does not correspond to genotype. With the increasing use of DNA assays based on single nucleotide polymorphisms for blood group prediction, it is important to characterize the bloo
Background: In most resource poor countries, particularly sub-Saharan Africa, modern contraceptive use and prevalence is unusually low and fertility is very high resulting in rapid population growth and high maternal mortality and morbidity. Current evidence shows slow progress in expanding the use of contraceptives by women of low socioeconomic status and insufficient financial commitment to fami
We present a variational assimilation system around a coarse resolution Earth System Model (ESM) and apply it for estimating initial conditions and parameters of the model. The system is based on derivative information that is efficiently provided by the ESM's adjoint, which has been generated through automatic differentiation of the model's source code. In our variational approach, the length of
