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Human dignity and AI : Mapping the contours and utility of human dignity in addressing challenges presented by AI

The ubiquitous use of artificial intelligence (AI) can bring about both positive and negative consequences for individuals and societies. On the negative side, there is a concern not only about the impact of AI on first-order discrete individual rights (such as the right to privacy, non-discrimination and freedom of opinion and expression) but also about whether the human rights framework is fit f

How Artificial Intelligence Systems Challenge the Conceptual Foundations of the Human Rights Legal Framework

Few recent developments have captured the human imagination as much as those within the field of artificial intelligence (AI). The increasing pervasiveness and ubiquity of AI affect both individual lives and society at large. Yet the human rights concerns raised in connection to AI have primarily concentrated around infringements of enumerated discrete rights, such as to privacy, non-discriminatio

Rough Around the Edges or a Fundamental Disconnect? : (Re-)examining the theory and utility of human rights through the six systemic distortions afforded by artificial intelligence systems

The ubiquitous deployment of artificial intelligence (AI) technologies affects an array of human rights, raising concerns around issues of discrimination, privacy, freedom of expression, information and data protection. However, just as regulators and policy-makers call for technological design to respect existing human rights, others debate whether human rights are robust enough to counter new ch

Monocytes and Neutrophils in Juvenile Idiopathic Arthritis

Juvenile idiopathic arthritis (JIA) is a heterogenous inflammatory joint disease and the most commonrheumatic disease in children. Oligoarticular JIA (oJIA) is the major subgroup, which mainly affects fewand large joints, such as the knee. The immunological processes and key players driving inflammationwithin the affected joints are not well characterised. Research has primarily focused on adaptiv

Social Sustainability in a Gender-Biased Occupation

This paper discussed construction industry’s ongoing battle with gender equality. Growing awareness of social sustainability responsibility has led to the mounting importance of human resources in the organisations. One perspective involves the focus on gender equality. Today women’s participation in the construction industry is still low except in times of acute labour shortages. This disproporti

Vaccine-induced correlate of protection against fatal COVID-19 in older and frail adults during waves of neutralization-resistant variants of concern : an observational study

BACKGROUND: To inform future preventive measures including repeated vaccinations, we have searched for a clinically useful immune correlate of protection against fatal COVID-19 among nursing homes residents.METHODS: We performed repeated capillary blood sampling with analysis of S-binding IgG in an open cohort of nursing home residents in Sweden. We analyzed immunological and registry data from 16

Scientific language use and sensemaking in concept maps : Interaction between concept systems, scientific concepts and everyday concepts

The interaction between student language use and sensemaking is an area in science learning that needs further elucidation in order to meet government standards in science education. In this study, concept mapping was used to explore the relationship between scientific language use and sensemaking defined as the interaction between the scientific concept system and everyday concepts in order to ma

Astrocytic engagement of the corticostriatal synaptic cleft is disrupted in a mouse model of Huntington s disease

Astroglial dysfunction contributes to the pathogenesis of Huntington s disease (HD), and glial replacement can ameliorate the disease course. To establish the topographic relationship of diseased astrocytes to medium spiny neuron (MSN) synapses in HD, we used 2-photon imaging to map the relationship of turboRFP-Tagged striatal astrocytes and rabies-Traced, EGFP-Tagged coupled neuronal pairs in R6/

Illness perception, health literacy, self-efficacy, adherence and quality of life in patients with intermittent claudication – a longitudinal cohort study

Background: Patients with intermittent claudication need lifelong treatment with secondary prevention to prevent cardiovascular events and progression of atherosclerotic disease. Illness perception, health literacy, self-efficacy, adherence to medication treatment, and quality of life are factors influencing patients’ self-management. Knowledge of these factors could be important when planning for

Maternal health leaders’ perceptions of barriers to midwife-led care in Ethiopia, Kenya, Malawi, Somalia, and Uganda

Objective: To identify and examine barriers to midwife-led care in Eastern Africa and how these barriers can be reduced Design: A qualitative inductive study with online focus group discussions and semi-structured interviews using content analysis Setting: The study examines midwife-led care in Ethiopia, Malawi, Kenya, Somalia, and Uganda -five African countries with an unmet need for midwives and

Meaningful Activities and Recovery (MA&R) : a co-led peer occupational therapy intervention for people with psychiatric disabilities. Results from a randomized controlled trial

Background: Activity and participation are critical to health and wellbeing. Limited evidence exists on how to support people with mental illness in participating in everyday activities. Aim: To investigate the effectiveness of Meaningful Activities and Recovery (MA&R), a co-led peer occupational therapy intervention focusing on activity engagement, functioning, quality of life, and personal r

Deactivation of implantable defibrillators at the end of life - A register-based study of ICD-deactivation at home and the impact of palliative care

Background: The Implantable Cardioverter-Defibrillator (ICD) is a well-established life-saving therapy for heart failure patients, but due to the risk for unnecessary shocks, deactivation of ICD:s is recommended at the end of life. We aimed to identify i) how many people with HF and an ICD who died in Sweden in 2018 received Specialized Palliative Care (SPC), ii) of those dying outside of hospital