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A Novel System for Source Characterization and Controlled Human Exposure to Nanoparticle Aggregates Generated During Gas–Metal Arc Welding
Abstract in Undetermined The aim of this study was to achieve a method to perform detailed characterization and human exposure studies of nanosized and nanostructured aerosol particles. The source chosen was mild steel, active gas, arc welding fume. The setup consisted of a generation chamber, where welding can be performed, connected to an airtight stainless steel 22 m(3) exposure chamber. Instru
Search for excited leptons in proton-proton collisions at root s=7 TeV with the ATLAS detector
The ATLAS detector is used to search for excited leptons in the electromagnetic radiative decay channel l* -> l gamma. Results are presented based on the analysis of pp collisions at a center-of-mass energy of 7 TeV corresponding to an integrated luminosity of 2.05 fb(-1). No evidence for excited leptons is found, and limits are set on the compositeness scale Lambda as a function of the excited le
Messages from the morgue to rheumatology: from Chagas disease to giant cell arteritis.
Autopsy rates have fallen from over 50% to less than 10% in recent decades. The drastic decline creates uncertainty regarding causes of death and has negative effects for research, training, and patient safety, despite advances in imaging and laboratory testing. Rheumatology is as much at a loss as other specialties. Examples are given of important missed diagnoses revealed only at autopsy.
The missing media: The procedural rhetoric of computer games
Carl R. Woese in memoriam Obituary
STrengthening the Reporting of OBservational studies in Epidemiology: Molecular Epidemiology STROBE-ME. An extension of the STROBE statement
Advances in laboratory techniques have led to a rapidly increasing use of biomarkers in epidemiological studies. Biomarkers of internal dose, early biological change, susceptibility, and clinical outcomes are used as proxies for investigating the interactions between external and/or endogenous agents and the body components or processes. The need for improved reporting of scientific research led t
Genome-wide Association Study Identifies Loci at ATF7IP and KLK2 Associated with Percentage of Circulating Free PSA
BACKGROUND: Percentage of free-to-total prostate-specific antigen (%fPSA) is an independent predictor of risk for prostate cancer among men with modestly elevated level of total PSA (tPSA) in blood. Physiological and pathological factors have been shown to influence the %fPSA value and diagnostic accuracy. MATERIALS/METHODS: To evaluate genetic determinants of %fPSA, we conducted a genome-wide ass
Food first! Theorising assets and actors in agroforestry: risk evaders, opportunity seekers and 'the food imperative' in sub-Saharan Africa
Despite widely recognised and well-established benefits, it is difficult to adopt the multifunctional activity of agroforestry into the landscape and lifeworld of small-scale agriculture, if poverty, itself a main reason for adopting agroforestry, stands in its way. Based on participant observations and interviews with small-scale farmers in western Kenya, we explore and theorise agroforestry adop
Evaluation of pre-PCR processing approaches for enumeration of Salmonella enterica in naturally contaminated animal feed.
Three pre-PCR processing strategies for the detection and/or quantification of Salmonella in naturally contaminated soy bean meal were evaluated.
A new route for the synthesis of methacrylic acid from 2-methyl-1,3-propanediol by integrating biotransformation and catalytic dehydration
Methacrylic acid was produced in high yield by an integrated process involving bioconversion of 2-methyl-1,3-propanediol (2M1,3PD) to 3-hydroxy-2-methylpropionic acid (3H2MPA) via 3-hydroxy-2-methylpropanal (3H2MPAL), and catalytic dehydration of the resulting acid. Whole cells of Gluconobacter oxydans grown on glycerol-based culture medium were used as the catalyst for oxidative biotransformation
Molecular mechanisms of protein aggregation from global fitting of kinetic models.
The elucidation of the molecular mechanisms by which soluble proteins convert into their amyloid forms is a fundamental prerequisite for understanding and controlling disorders that are linked to protein aggregation, such as Alzheimer's and Parkinson's diseases. However, because of the complexity associated with aggregation reaction networks, the analysis of kinetic data of protein aggregation to
Blood cell telomere length among patients with an isolated popliteal artery aneurysm and those with multiple aneurysm disease
Objectives: Short relative telomere length (RTL) is associated with vascular ageing, inflammation and cardiovascular risk factors. Previous studies have reported an association between abdominal aortic aneurysm and short RTL. The presence of atherosclerosis among patients with aneurysm disease may, however, be a confounder. The aim was to explore the associations between short RTL and aneurysm dis
Cross-generational transmission from drug abuse in parents to attention-deficit/hyperactivity disorder in children.
Attention-deficit/hyperactivity disorder (ADHD) predisposes to drug abuse (DA) and twin studies suggest shared genetic effects. We here seek to determine, using adoption and adoption-like samples, the magnitude of the cross-generational transmission from DA in parents to ADHD in their children and clarify the degree to which this arises from genetic v. rearing effects.
Large Igneous Provinces and supercontinents: Toward completing the plate tectonic revolution
Regional groupings of a majority, or all, of Earth's crustal blocks have occurred several times in Earth history, but only the most recent supercontinent Paleozoic Pangea/Gondwana, is well characterized. Prior Precambrian supercontinents are postulated: Rodinia (ca. 1 to 0.7 Ga), Nuna/Columbia (ca. 1.8 to 1.3 Ga) and Kenorland/supercratons (ca. >2.7 to 2.0 Ga), but the configuration of each is poo
Aspects of ancient Greek trade re-evaluated with amphora DNA evidence
Ancient DNA trapped in the matrices of ceramic transport jars from Mediterranean shipwrecks can reveal the goods traded in the earliest markets. Scholars generally assume that the amphora cargoes of 5th-3rd century B.C. Greek shipwrecks contained wine, or to a much lesser extent olive oil. Remnant DNA inside empty amphoras allows us to test that assumption. We show that short 100 nucleotides of an
Patterns of Institutional Change in Minimum Income Protection in Sweden and Germany
Germany is generally regarded as a case of qualitative “change” in minimum income protection (MIP) schemes, while Sweden is perceived as one of institutional “inertia”.This paper seeks to qualify this view by embedding developments in MIP in wider policy and governance trends. Empirically, it is based on document analysis and qualitative expert interviews in the two countries. Theoretically, the p
Association’s between wage system and risk factors for musculoskeletal disorders among construction workers
Abstract in UndeterminedPiece rate and performance based wage systems are common in the construction industry. Construction workers are known to have an increased risk of pain and musculoskeletal disorders (MSD). In this cross-sectional questionnaire study, we examined the association between wage system and (1) physical exertion, (2) time pressure, (3) pain, and (4) fatigue. The participants comp
Measures of Hip Function and Symptoms
Association between preterm birth and intrauterine growth retardation and child asthma.
An association between preterm birth and an increased risk for childhood asthma has been demonstrated but the importance of intrauterine growth retardation on asthma risk is unclear.Using data from Swedish health registers, infant characteristics and childhood asthma were studied. Analyses were made using Mantel-Haenszel methodology with adjustment for year of birth, maternal age, parity, smoking