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Effect of 3,4-Methylenedioxyamphetamine on Dendritic Spines Dynamics in Rat Neocortical Neurons - Involvement of Heat Shock Protein 27.

Along with chronic neurotoxic effects, the long-term consumption of amphetamines has been associated to psychiatric symptoms and memory disturbances. Dendritic spine dynamics have been discussed as a possible morphological correlate. However, the underlying mechanisms are still elusive. 3,4-Methylenedioxyamphetamine (MDA), a major drug of abuse and a main metabolite after 3,4-methylenedioxymethamp

Electrocardiographic classification of acute coronary syndromes: a review by a committee of the International Society for Holter and Non-Invasive Electrocardiology

The electrocardiogram (ECG) remains the most immediately accessible and widely used diagnostic tool for guiding emergency treatment strategies. The ECG recorded during acute myocardial ischemia is of diagnostic, therapeutic, and prognostic significance. In patients with myocardial ischemia as a result of decreased blood supply, the initial 12-lead ECG typically shows (1) predominant ST-segment ele

High-spin structure beyond band termination in Er-157

The angular-momentum induced transition from a deformed state of collective rotation to a noncollective configuration has been studied. In Er-157 this transition manifests itself as favored band termination near I=45 (h) over bar. The feeding of these band terminating states has been investigated for the first time using the Gammasphere spectrometer. Many weakly populated states lying at high exci

Probing doubly excited ionic states of N-2(+) via a triple excitation above the N 1s threshold in the N-2 molecule

Angle-resolved resonant Auger-electron spectroscopy has been carried out on the nitrogen molecule at selected photon energies around 419 eV, where a 1s core electron and two valence electrons are promoted into the lowest unoccupied molecular orbital 1pi(g). Significant enhancement of a specific band, which cannot be disentangled in direct photoionization, is observed at a binding energy of 37.6 eV

Low levels of IgM antibodies against phosphorylcholine-A potential risk marker for ischemic stroke in men

Background: Natural antibodies specific for phosphorylcholine (anti-PC) have been implicated as protective factors in atherosclerosis. We herein determined the relationship between IgM anti-PC and incidence of cardiovascular disease (CVD). Methods: We studied 349 incident cases (200 men) of first events of CVD (coronary heart disease (CHD; n = 203 or ischemic stroke; n = 146) and 693 age- and sex-

Confirming the three-factor structure of the Disgust Scale-Revised in eight countries

The current study evaluates the factor structure of the Disgust Scale-Revised (DS-R) in eight countries: Australia, Brazil, Germany, Italy, Japan, the Netherlands, Sweden, and the United States (N = 2,606). Confirmatory factor analysis is used to compare two different models of the DS-R and to investigate the invariance of the factor structure of the DS-R across countries and gender. A three-facto

Relation between drug treatment and cancer in hypertensives in the Swedish Trial in Old Patients with Hypertension 2: a 5-year, prospective, randomised, controlled trial

BACKGROUND: Is cancer related to hypertension and blood pressure? Do antihypertensive drugs promote cancer? Do antihypertensive drugs protect against cancer? We previously analysed the frequency of cardiovascular mortality and morbidity in elderly people who participated in the Swedish Trial in Old Patients with Hypertension 2 (STOP-Hypertension-2). We have also looked at the frequency of cancer i

X-ray absorption and resonant Auger spectroscopy of O(2) in the vicinity of the O 1s-->sigma(*) resonance: Experiment and theory.

We report on an experimental and theoretical investigation of x-ray absorption and resonant Auger electron spectra of gas phase O(2) recorded in the vicinity of the O 1s-->sigma(*) excitation region. Our investigation shows that core excitation takes place in a region with multiple crossings of potential energy curves of the excited states. We find a complete breakdown of the diabatic picture for

Evidence for isovector neutron-proton pairing from high-spin states in N=Z Rb-74

High-spin states in the odd-odd N=Z nucleus Rb-74(37)37 were studied using the Ca-40(Ca-40,alphanp) reaction. A previously observed odd-spin T=0 band has been extended to I-pi=(31(+)) and an even-spin T=0 band has been observed for the first time to I-pi=(22(+)); both have a pi(g(9/2))circle timesnu(g(9/2)) structure. A strongly coupled low-spin T=0,K=3 band has been interpreted as being based upo

Cleavage of the Vesicular GABA Transporter under Excitotoxic Conditions Is Followed by Accumulation of the Truncated Transporter in Nonsynaptic Sites.

GABA is the major inhibitory neurotransmitter in the CNS and changes in GABAergic neurotransmission affect the overall activity of neuronal networks. The uptake of GABA into synaptic vesicles is mediated by the vesicular GABA transporter (VGAT), and changes in the expression of the transporter directly regulate neurotransmitter release. In this work we investigated the changes in VGAT protein leve

Shortcuts for the circle

Let C be the unit circle in R2. We can view C as a plane graph whose vertices are all the points on C, and the distance between any two points on C is the length of the smaller arc between them. We consider a graph augmentation problem on C, where we want to place k ≥ 1 shortcuts on C such that the diameter of the resulting graph is minimized. We analyze for each k with 1 ≤ k ≤ 7 what the optimal

Cumulative space in black-white pebbling and resolution

We study space complexity and time-space trade-offs with a focus not on peak memory usage but on overall memory consumption throughout the computation. Such a cumulative space measure was introduced for the computational model of parallel black pebbling by [Alwen and Serbinenko 2015] as a tool for obtaining results in cryptography. We consider instead the nondeterministic black-white pebble game a

The interaction between uPAR and vitronectin triggers ligand-independent adhesion signalling by integrins

The urokinase-type plasminogen activator receptor (uPAR) is a non-integrin vitronectin (VN) cell adhesion receptor linked to the plasma membrane by a glycolipid anchor. Through structure-function analyses of uPAR, VN and integrins, we document that uPAR-mediated cell adhesion to VN triggers a novel type of integrin signalling that is independent of integrin-matrix engagement. The signalling is ful

Spectroscopy of core-excited molecules and exploration of the induced dynamics

This thesis investigates core excited electronic states of molecules in gas phase. In particular, the resonanttransitions of ionised molecules, the site-selectivity surrounding Auger-Meitner decay, and the nuclear dynamicsthat may follow core excitation and ionisation.Background: Fundamental understanding of molecules and ions lay the groundwork for all future applicativescience and production. Fo

Free choice of treatment content, support on demand and supervision in internet-delivered CBT for adults with depression : A randomized factorial design trial

Even if much is known regarding the effects of internet-delivered cognitive behaviour therapy (ICBT) for depression there are several topics that have not been studied. In this factorial design trial with 197 participants we investigated if clients in ICBT could select treatment modules themselves based on a selection of 15 tailored treatment modules developed for use in ICBT for depression. We co

Pneumococcal serotype epidemiology and resistance after PCV13 replacement with PCV10, Sweden

Objectives: To evaluate the impact of the 2018 switch from PCV13 to PCV10 in Sweden’s childhood immunisation programme on the serotype distribution of Streptococcus pneumoniae.MethodsRespiratory tract (RT) S. pneumoniae isolates (n=1615; 2020–2023) were serotyped, tested for antimicrobial susceptibility and compared with invasive pneumococcal disease (IPD) isolates (n=397) and PCV13-era data (2016

Program 20 Years Of Sound Environments

375897_A5_Program Sanne KG.indd 20 Years of Sound Environments THE SOUND ENVIRONMENT CENTRE | LUND UNIVERSITY | 19 NOVEMBER 2024 20 Years of Sound Environments 10.00–10.30 WELCOME BY SANNE KROGH GROTH Sound Environments: Exploring, listening, positioning Sound Environments marks the 20th anniversary of the Sound Environment Centre at Lund University. The centre was initiated in 2004 and establishe

https://www.lmc.lu.se/en/sites/lmc.lu.se.en/files/2024-11/Program%2020%20years%20of%20sound%20environments.pdf - 2026-05-09

Lunds-universitets-magasin-10-2010

LUM Lunds universitets magasin | Nr 10 | 2010 teMa: MeLLanöstern OH-modellen – hård men rättvis? Domare fick drömjobb i Lund 2 LUM nr 10 | 2010 ett Lyft för MUsiken LUM nr 10 | 2010 3 ”Lyftande svanar” av Bruno Lilje­ fors lyfter musiken till oanade höj­ der i den nya konsertsalen som ny­ ligen invigdes vid Musikhög skolan i Malmö. I två år har man arbetat med Liljeforssalen, som tidigare var ett

https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-10-2010.pdf - 2026-05-09

Long term azathioprine maintenance therapy in ANCA-associated vasculitis : combined results of long-term follow-up data

Methods: Three hundred and eighty newly diagnosed ANCA-associated vasculitis patients from six European multicentre studies treated with AZA maintenance were included; 58% were male, median age at diagnosis 59.4 years (interquartile range: 48.3-68.2 years); granulomatosis with polyangiitis, n = 236; microscopic polyangiitis, n = 132; or renal limited vasculitis, n = 12. Patients were grouped accor