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In search of surrogate safety indicators for vulnerable road users : a review of surrogate safety indicators

Surrogate indicators are meant to be alternatives or complements of safety analyses based on accident records. These indicators are used to study critical traffic events that occur more frequently, making such incidents easier to analyse. This article provides an overview of existing surrogate indicators and specifically focuses on their merit for the analyses of vulnerable road users and the exte

Multiple sulfur-isotopic evidence for a shallowly stratified ocean following the Triassic-Jurassic boundary mass extinction

The cause of the Triassic-Jurassic (Tr-J) boundary biotic crisis, one of the ‘Big Five’ mass extinctions of the Phanerozoic, remains controversial. In this study, we analyzed multiple sulfur-isotope compositions (δ33S, δ34S and δ36S) of pyrite and Spy/TOC ratios in two Tr-J successions (Mariental, Mingolsheim) from the European Epicontinental Seaway (EES) in order to better document ocean-redox va

Application of AdaptIVe Evaluation Methodology.

Since the last decade, development efforts by academia and industry for automated driving functions have increased significantly. Also, the European research project AdaptIVe is looking into this topic. Within AdaptIVe, 21 different automated driving functions for different speed ranges and target areas have been developed. They have been developed in three sub projects (SPs), addressing different

Sports participation and physical activity in adult Dutch and Swedish patients with severe haemophilia : A comparison between intermediate- and high-dose prophylaxis

INTRODUCTION: Differences in treatment and outcome have been reported for persons with haemophilia (PWH) on intermediate-dose (Dutch) and high-dose (Swedish) prophylaxis, but the potential influence of sports participation has not been considered.AIM: To compare sports participation and clinical outcome between adult Dutch and Swedish PWH.METHODS: Self-reported sports participation (type and frequ

D-Serine : The right or wrong isoform?

Only recently, d-amino acids have been identified in mammals. Of these, d-serine has been most extensively studied. d-Serine was found to play an important role as a neurotransmitter in the human central nervous system (CNS) by binding to the N-methyl-d-aspartate receptor (NMDAr), similar to glycine. Therefore, d-serine may well play a role in all physiological and pathological processes in which

QCD dynamic effects in the neutrino absorption by the Earth’s interior at IceCube neutrino energies and above

We investigate how the uncertainties in σνN due the different QCD dynamic models would modify the neutrino absorption while they travel across the Earth. We compare the predictions of models based on the solution of the linear DGLAP equations at small-x and large-Q2 with those which impose the Froissart bound at large energies, taking into account the unitarity effects in the neutrino - nucleon cr

High-density scalp EEG data acquired in an inattentional blindness paradigm with background Gestalt stimuli

Behavioral and electroencephalography (EEG) data were analyzed from 30 participants performing a demanding, attention-capturing task in which they had to detect an occasional decrement of luminance of small discs. Crucially, numerous white segments in the background were presented either in random orientations or configuring a contour shape of a square or a diamond. The participants' awareness of

Amino Acid Synthesis Deficiencies

In recent years the list of disorders affecting amino acid synthesis has grown rapidly. Not only the number of defects has increased, but also the associated clinical phenotypes have expanded spectacular, the latter mainly due to the advances of next-generation sequencing diagnostics. An important reason for the contribution of NGS in the diagnosis of amino acid synthesis disorders is the fact tha

Ethanol in Aqueous Solution Studied by Microjet Photoelectron Spectroscopy and Theory

ConspectusBy combining results and analysis from cylindrical microjet photoelectron spectroscopy (cMJ-PES) and theoretical simulations, we unravel the microscopic properties of ethanol-water solutions with respect to structure and intermolecular bonding patterns following the full concentration scale from 0 to 100% ethanol content. In particular, we highlight the salient differences between bulk a

Exploiting the Transformative Features of Metal Halides for the Synthesis of CsPbBr3@SiO2 Core-Shell Nanocrystals

The encapsulation of colloidal lead halide perovskite nanocrystals within silica (SiO2) is one of the strategies to protect them from polar solvents and other external factors. Here, we demonstrate the overcoating of CsPbBr3 perovskite nanocrystals with silica by exploiting the anhydride-induced transformation of Cs4PbBr6 nanocrystals. CsPbBr3@SiO2 core–shell nanocrystals are obtained after (i) a

MOCCA-SURVEY Database I: Is NGC 6535 a dark star cluster harbouring an IMBH?

We describe the dynamical evolution of a unique type of dark star cluster model in which the majority of the cluster mass at Hubble time is dominated by an intermediate-mass black hole (IMBH). We analysed results from about 2000 star cluster models (Survey Database I) simulated using the Monte Carlo code MOnte Carlo Cluster simulAtor and identified these dark star cluster models. Taking one of the

On the proper orientation number of bipartite graphs

An orientation of a graph G is a digraph D obtained from G by replacing each edge by exactly one of the two possible arcs with the same endvertices. For each v∈V(G), the indegree of v in D, denoted by dD-(v), is the number of arcs with head v in D. An orientation D of G is proper if dD-(u)≠dD-(v), for all uv∈E(G). The proper orientation number of a graph G, denoted by χ→(G), is the minimum of the

Eco-evolutionary perspectives on emergence, dispersion and dissolution of historical Dutch commons

Historical commons represent self-governed governance regimes that regulate the use and management of natural and man-made shared resources. Despite growing scientific interests, analyses of commons evolution and temporal dynamics are rare and drivers of change (birth, adaptation, dissolution) remain obscure. We apply an interdisciplinary approach and address these issues from an eco-evolutionary