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Opioids for newborn infants receiving mechanical ventilation

Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To determine the benefits and harms of opioid analgesics in neonates (term or preterm) receiving mechanical ventilation, compared to placebo, no drug, other opioids, other analgesics or sedatives.

EXAFS investigations on highly-ordered ultrathin films of Me-DCNQI on single crystal surfaces

DMe-DCNQI forms highly-ordered ultrathin films on various single crystal surfaces. NEXAFS reveals flat lying molecules for all investigated film thicknesses (up to 40 layers) on nearly all substrates under investigation (Ag(111), Ag(100), Cu(100), Cu(111)). The C1s and N1s NEXAFS spectra of these condensed layers show several very sharp resonances. The comparison with the quinoide molecules TCNQ a

The bidirectional association between body weight and mobility disability : A population-based cohort

BACKGROUND: Obesity is more common in people with mobility disability than in non-disabled individuals, but less is known about the longitudinal effects leading to this health state.OBJECTIVE: To explore the potential bidirectional association between mobility disability and obesity.METHODS: Participants were identified in the population-based Stockholm Public Health Cohort (2002-2010, n = 17 945)

Who are the world leaders in innovation? Exploring the changing role of firms in emerging economies

Recent literature shows that differences in structural characteristics at country level are important determinants of the innovative capacities and growth performance of different countries. Based on firm-level data collected from a survey, this study identifies who are the world leaders, followers, and marginalised firms in a sample of nine countries and a selection of industries in terms of firm

Children's education and parental old-age health : Evidence from a population-based, nationally representative study in India

Previous research has documented intergenerational transmission of human capital from children to parents. Less is known, however, about heterogeneity in this 'upward transmission' in low-resource settings. We examine whether co-resident adult children's education is associated with improved health among older parents in India, using nationally representative data from the 2014 Indian National Sam

A SEMI-ANALYTIC MODEL OF TIDAL INLETS AND THEIR EVOLUTION

The water exchange between the sea and a lagoon or bay through an inlet due to tides is a classical topic that has been investigated in a large number of studies (Keulegan, 1967; O’Brien and Dean, 1972; O’Brien and Clark, 1974; Escoffier, 1977). In this paper, a simple semi-analytic model of the flow induced by tides through an inlet connecting the sea to a lagoon or bay is developed. The model is

First-in-Man Experience with the ClearLumen Thrombectomy System as an Adjunctive Therapy in Primary Percutaneous Coronary Interventions

Objectives To describe the first-in-man experience with the ClearLumen Thrombectomy System (Walk Vascular, Irvine, CA) and report on its safety, feasibility and efficacy when used as an adjunctive therapy during primary PCI. Background Thrombus aspiration (TA) aims to improve microvascular perfusion but currently available devices are not optimal. Methods Prospective, single-centre, non-randomized

The influence of backscatter material on 99mTc and 201Tl line source responses

SPECT projections are contaminated by scatter, resulting in reduced image contrast and quantitative errors. When tissue is present behind the source, some of the detected photons backscatter via this tissue. Particularly in dual-isotope SPECT and in combined emission-transmission SPECT, backscatter constitutes a major part of the down-scatter contamination in lower-energy windows. In this paper, t

Bioreactor control using a probing feeding strategy and mid-ranging control

The paper presents a fed-batch fermentation technique for bioreactors operating close to their maximum oxygen transfer capacity. The method combines the advantages of the probing feeding strategy and the temperature limited fed-batch technique. When the maximum oxygen transfer capacity of the reactor is reached, the temperature is decreased to lower the oxygen demand. To achieve a good control of

Synthesis of P1 '-Functionalized Macrocyclic Transition-State Mimicking HIV-1 Protease Inhibitors Encompassing a Tertiary Alcohol

Seven novel tertiary alcohol containing linear HIV-1 protease inhibitors (PIs), decorated at the para position of the benzyl group in the P1' side with (hetero)aromatic moieties, were synthesized and biologically evaluated. To study the inhibition and antiviral activity effect of P1-P3 macro-cyclization, 14- and 15-membered macrocyclic Pis were prepared by ring-closing metathesis of the correspond

Sex determination in barn swallows Hirundo rustica by means of discriminant analysis in two European populations

Aims: Differences in morphology in adult barn swallows were investigated using bone and feather measurements taken from birds from a northern (Danish) and a southern (Spanish) European population. Discriminant Function Analysis was used to help in discriminating the sex of individuals of both populations. Location: Badajoz (Spain) and Kraghede (Denmark). Methods: Two discriminant functions were ob

Adaptation and Learning for Manipulators and Machining

This thesis presents methods for improving the accuracy and efficiency of tasks performed using different kinds of industrial manipulators, with a focus on the application of machining. Industrial robots offer a flexible and cost-efficient alternative to machine tools for machining, but cannot achieve as high accuracy out of the box. This is mainly caused by non-ideal properties in the robot joint

Evolutionary transitions in enzyme activity of ant fungus gardens

Fungus-growing (attine) ants and their fungal symbionts passed through several evolutionary transitions during their 50 million year old evolutionary history. The basal attine lineages often shifted between two main cultivar clades, whereas the derived higher-attine lineages maintained an association with a monophyletic clade of specialized symbionts. In conjunction with the transition to speciali