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We present the application of two fibre-optic-coupled time-resolved spectrofluorometers and a compact steady-state diffuse reflected light/fluorescence spectrometer to in vivo and ex vivo studies of skin cancer and osteoarthritis. In a clinical study of skin cancer, 27 lesions on 25 patients were investigated in vivo before surgical excision of the region measured. Preliminary analysis reveals a s

HIV-2 infection will progress to AIDS in most patients without treatment, albeit at approximately half the rate of HIV-1 infection. HIV-2 capsid (p26) amino acid polymorphisms are associated with lower viral loads and enhanced processing of T cell epitopes, which may lead to protective Gag-specific T cell responses common in slower progressors. Lower virus evolutionary rates, and positive selectio

Extracellular matrix (ECM) remodeling has been associated with chronic lung diseases. However, information about specific age-associated differences in lung ECM is currently limited. In this study, we aimed to identify and localize age-associated ECM differences in human lungs using comprehensive transcriptomic, proteomic, and immunohistochemical analyses. Our previously identified age-associated

Reconciling biodiversity conservation with agricultural production requires a better understanding of how key ecosystem service providing species respond to agricultural intensification. Carabid beetles and spiders represent two widespread guilds providing biocontrol services. Here we surveyed carabid beetles and spiders in 66 winter wheat fields in four northwestern European countries and analyze

Pancreatic Ductal Adenocarcinoma (PDAC) is a very aggressive disease, lacking effective therapeutic approaches and leaving PDAC patients with a poor prognosis. The life expectancy of PDAC patients has not experienced a significant change in the last few decades with a five-year survival rate of only 8%. To address this unmet need, novel pharmacological targets must be identified for clinical inter

BACKGROUND: Precision medicine has the potential to improve cardiovascular disease (CVD) risk prediction in individuals with type 2 diabetes (T2D).METHODS: We conducted a systematic review and meta-analysis of longitudinal studies to identify potentially novel prognostic factors that could improve CVD risk prediction in T2D. Out of 9380 studies identified, 416 studies met inclusion criteria. Outco

The advent of single-cell biology opens a new chapter for understanding human biological processes and for diagnosing, monitoring, and treating disease. This revolution now reaches the field of cardiovascular disease (CVD). New technologies to interrogate CVD samples at single-cell resolution are allowing the identification of novel cell communities that are important in shaping disease developmen

BACKGROUND: ACURATE neo2 is a transcatheter aortic valve implantation system consisting of a self-expanding bioprosthetic valve with supra-annular leaflet position and featuring innovations to facilitate placement accuracy and reduce paravalvular regurgitation. METHODS AND RESULTS: The goal of the Early neo2 (Early neo2 Registry of the ACURATE neo2 TAVI Prosthesis) was to gather real-life data on

Downregulation of the DNA repair protein WD40-encoding RNA antisense to p53 (WRAP53) has been associated with radiotherapy resistance and reduced cancer survival. The aim of this study was to evaluate WRAP53 protein and RNA levels as prognostic and predictive markers in the SweBCG91RT trial, in which breast cancer patients were randomized for postoperative radiotherapy. Using tissue microarray and

BackgroundRecently, it has been suggested that gender disparity in Occupational Therapy has to do with segregated gendered job norms that position female dominated professions as a ‘step down’ for many males. Interestingly, this suggestion was not underpinned by experiences of males in the profession.Aims and MethodsThirteen male Occupational Therapists with a variety of backgrounds were invited t

Defaulter tracing policies for Prevention of Mother-to-Child Transmission (PMTCT) services are vital for achieving the global goal of zero new HIV infections. However, little is known about their implementation. This qualitative study explores the role of tracers—community volunteers, retention workers, and mentor mothers—in implementing such policy across six facilities in Western Kenya. It uses Defaulter tracing policies for Prevention of Mother-to-Child Transmission (PMTCT) services are vital for achieving the global goal of zero new HIV infections. However, little is known about their implementation. This qualitative study explores the role of tracers—community volunteers, retention workers, and mentor mothers—in implementing such policy across six facilities in Western Kenya. It uses

Severe chronic rhinosinusitis with nasal polyps (CRSwNP), a form of diffuse bilateral (usually type 2) CRS, is a debilitating disease with a significant impact on quality of life (QoL). With novel knowledge and treatment options becoming available, there is a growing need to update or revise key definitions to enable communication across different specialties dealing with CRS, and to agree on nove

The gut-to-lung axis is critical during respiratory infections, including influenza A virus (IAV) infection. In the present study, we used high-resolution shotgun metagenomics and targeted metabolomic analysis to characterize influenza-associated changes in the composition and metabolism of the mouse gut microbiota. We observed several taxonomic-level changes on day (D)7 post-infection, including

Concern has risen that current global warming and more frequent extreme events such as droughts and floods will increase conflict around the world. This concern has spurred both social science research on contemporary climate, peace, and conflict as well as research in the historical sciences on past climate, weather, warfare, and violence. This perspectives article compares these two fields of sc

Professor, CMES Director, MECW Scientific Coordinator Contact details Email: ronny [dot] berndtsson [at] tvrl [dot] lth [dot] se Phone: +46 46 222 89 86Organisation Division of Water Resources Engineering Room number: 3146 Service point: 3 WebpageRonny Berndtssons profile in Lund University research portalOther affiliations Profile area member LTH Profile Area: Water Member of Strategic Research A

https://www.cmes.lu.se/ronny-berndtsson - 2026-05-17

~, v Master of Scierrtce 'fr. ests Renewable Hydrogen Energy System For Households Application JunIin Ma E-mail: junlin.ma.697@student.1u.se Lund University International Master Programme in Environmental Science Supervisors: Bertil Holmström, Chalmers/University of Göteborg, Sweden Phonenumber: 031 21 61 73 E-mail: bertilh@pictor.phc.chalmers.se Jan Johanson, EcomITecH AB, Sweden Phonenumber: 082

https://www.lumes.lu.se/sites/lumes.lu.se/files/ma_junlin.pdf - 2026-05-17

1 3 Acta Neuropathol (2014) 127:283–295 DOI 10.1007/s00401-013-1219-1 CAse RepORt The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast‑derived neurons Mariangela Iovino · Ulrich Pfisterer · Janice L. Holton · Tammaryn Lashley · Robert J. Swingler · Laura Calo · Rebecca Treacy · Tamas Revesz · Malin Parmar · Michel Goedert · Mira

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_acta_neuropathol.pdf - 2026-05-17

Handbook for PhD students Handbook for PhD students FACULTY OF MEDICINE | LUND UNIVERSITY 04 06 10 Introduction Welcome PhD studies at the Faculty of Medicine Aim of PhD studies Rules and regulations Organisation of PhD studies at the Faculty of Medicine The Faculty The Faculty Board The Dean and Faculty Management Research Studies Board Study Coordinator for PhD studies Departments/Head of Postgr

https://www.medicin.lu.se/sites/medicin.lu.se/files/2023-06/Handbook%20for%20PhD%20students%202020%20(1).pdf - 2026-05-17