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Non-small-cell lung cancer (NSCLC) is the leading cause of cancer-related death worldwide, with ~40–50% of patients diagnosed with non-metastatic disease (stages IA–IIIC). The treatment landscape is evolving rapidly as immunotherapies and targeted therapy are introduced in the non-metastatic setting, creating a need to assess patient outcomes prior to their introduction. This real-world study usin

Exposure to infectious diseases in early life has been linked to increased mortality risk in later life in high-disease settings, such as eighteenth- and nineteenth-century Europe. Less is known about the long-term effects of early-life disease exposure in milder disease environments. This study estimates heterogeneous effects from disease exposure in infancy on later-life mortality in twentieth-c

BakgrundVaccination är en av de viktigaste folkhälsoinsatserna för att rädda liv och hindra spridning av smittsamma sjukdomar. Tack vare vaccinationer har miljontals liv räddats världen över. Men det räcker inte att säkra och effektiva vaccin tas fram och tillgängliggörs. En förutsättning för framgångarna är att individer accepterar att bli vaccinerade. Under senare tid har forskningsområdet om va

Alla dör, men våra upplevelser av livets slut ser olika ut beroende på hur vårt liv och våra relationer sett ut. Denna avhandling undersöker hur genus, ålder och relationer påverkar människors erfarenheter och möjligheter under livets slutskede. I en tid då såväl hälso- och sjukvårdssystemen som informellt vård- och omsorgsgivande är satta under press är det extra viktigt att utveckla kunskap om hThe way that we die and care for the dying today is changing, related to extended life expectancy, neoliberalization, as well as shifting caring roles in relation to gender. In a time of “care crisis”, both formal and informal care resources are under duress, making the question of how to provide “a good death” complex and contested in new ways. Scholars in public health have posited a health prom

BackgroundThe levonorgestrel-releasing intrauterine device (LNG-IUD) is widely used for the treatment of menorrhagia, dysmenorrhea, and for contraception. However, the association between the use of LNG-IUD and the risk of site-specific gynecologic and breast cancers remains inconclusive.ObjectiveWe aim to address this knowledge gap by investigating whether the use of LNG-IUD is associated with a

Currently, both the US and the EU are pursuing industrial policies to support climate mitigation objectives. The climate transition will require increased use of material resources, but the envisioned industrial policies do not sufficiently address resource use, despite the current unsustainable global resource-use trajectory. The lack of industrial policy in this field is therefore relevant and t

Introduction: The aims were to investigate 1) the frequency of nonsurgical retreatment, root-end surgery, extraction, and further restorative treatment during a follow-up of 10–11 years after root filling and compare the frequencies according to tooth group and type of coronal restoration and 2) the timing of nonsurgical retreatment, root-end surgery, and extraction. Methods: Data were collected f

Introduction: Resting heart rate has been distinctly related to both internalizing (high pulse) and externalizing (low pulse) disorders. We aimed to explore the associations between resting heart rate and suicidal behavior (nonfatal suicide attempt [SA] and suicide death [SD]) and evaluate if such associations exist beyond the effects of internalizing/externalizing symptomatology. Method: We used