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A rare regulatory variant in the MEF2D gene affects gene regulation and splicing and is associated with a SLE sub-phenotype in Swedish cohorts

Systemic lupus erythematosus (SLE) is an autoimmune disorder with heterogeneous clinical presentation and complex etiology involving the interplay between genetic, epigenetic, environmental and hormonal factors. Many common SNPs identified by genome wide-association studies (GWAS) explain only a small part of the disease heritability suggesting the contribution from rare genetic variants, undetect

Measles and rubella seroimmunity in newly arrived adult immigrants in Sweden

Background: International migrants could be considered as a risk group for being susceptible to vaccine preventable diseases such as measles and rubella. However, data on immunity in different migrant groups are scarce. Apart from asylum seekers and refugees, other immigrant groups might also be at risk. We have examined measles and rubella specific IgG antibodies among newly arrived adult immigra

Techniques for and consequences of using INSPIRE extensions : a case study with Swedish hydrological data

The demand for easily available geographic information is increasing in society. Moreover, knowledge of spatial data infrastructures (SDIs) has increased in many European governmental agencies, in large part because of the implementation of the INSPIRE directive. Many countries, thus, recognise the need to provide more detailed geographic information as network services at the national level. One

A Phenomenographic Study of Swedish Nurse Anesthetists' and OR Nurses' Work Expereinces

In the complex OR environment, perioperative team members need to practice communication and teamwork to ensure safe, high-qualitycare. A lack of collaboration among professionals in the OR during surgery results in inefficiency, increased tension, and suboptimal patient care. The purpose of this study was to determine how nurse anesthetists and OR nurses experienced their work in the OR. We used

Exploring retail innovation management: Perceptions and practices in Swedish retail organizations

Innovation plays an important role in organization survival and longevity. This is especially true in the retail industry; there is a growing acknowledgment of the role of innovation in retail practice, as maintaining the status quo might prove insufficient, especially for traditional retailers, in addressing the enormous challenges they are facing driven by technological developments and evolving

Nutritional impact on Immunological maturation during Childhood in relation to the Environment (NICE) : A prospective birth cohort in northern Sweden

Introduction Prenatal and neonatal environmental factors, such as nutrition, microbes and toxicants, may affect health throughout life. Many diseases, such as allergy and impaired child development, may be programmed already in utero or during early infancy. Birth cohorts are important tools to study associations between early life exposure and disease risk. Here, we describe the study protocol of

Two methods for normalisation of measured energy performance-Testing of a net-zero energy building in Sweden

An increasing demand for energy-efficient buildings has led to an increasing focus on predicted energy performance once a building is in use. Many studies have identified a performance gap between predicted energy use and actual measured energy use once buildings are in the user phase. However, none of the identified studies normalise measured energy use for both internal and external deviating bo

Hegemony and the Intellectual Function : Medialised Public Discourse on Privatisation in Sweden 1988-1993

This dissertation offers a theorisation of the ways in which the intellectual function is performed through various subject positions. In the thesis, a post-Marxist approach to discourse theory is used to address questions of discursive shifts, hegemony and the intellectual function. It is supplemented by a rhetorical political analysis in order to examine how practices and strategies involved in

Scrapping programmes and ITQs : Labour market outcomes and spill-over effects on non-targeted fisheries in Sweden

Scrapping programmes and individual transferable quotas (ITQs) are two management measures frequently used to reduce overcapacity in fisheries. These measures are often aimed at specific vessel segments targeting specific fish stocks. In this case, fishermen who scrap their vessels or sell their quotas may shift their fishing activities, possibly contributing to overcapacity in other fleets. The a